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Characterization Of Normal Development And Injury In The Premature Baboon Brain, Jennifer Griffith
Characterization Of Normal Development And Injury In The Premature Baboon Brain, Jennifer Griffith
All Theses and Dissertations (ETDs)
Nearly 13% of infants born in the United States each year are preterm - that is, born before 37 weeks gestation. Although improvements in clinical care have contributed to survival rates that now exceed 85%, premature infants are at high risk for motor, sensory, cognitive and behavioral disabilities. In order to develop therapeutic interventions to prevent these adverse neurodevelopmental outcomes, we must first understand the nature of cerebral injury associated with premature birth and the mechanisms by which it leads to altered brain development. A baboon: Papio papio) model of preterm birth was used to evaluate cerebral development from 90 …
The Importance Of Glucose Transport In Reproductive Events, Katie Adastra
The Importance Of Glucose Transport In Reproductive Events, Katie Adastra
All Theses and Dissertations (ETDs)
ABSTRACT OF THE DISSERTATION The Importance of Glucose Transport in Reproductive Events by Katie Lynn Adastra Doctor of Philosophy in Biology and Biomedical Sciences Developmental, Regenerative and Stem Cell Biology Washington University in St. Louis, 2012 Professor Kelle H. Moley, Chairperson Successful pregnancy outcome is contingent on a number of factors, the earliest of which include the events occurring during early pregnancy. This time period from fertilization to implantation requires drastic changes in both the embryo and the uterus, including cell proliferation and differentiation. Alterations in environment may lead to adverse effects during any of these stages. This emphasizes the …