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Role Of Proneurotrophin-P75ntr Signaling In A Mouse Model Of Depression, Kirsten Hodgson

All Graduate Theses and Dissertations, Fall 2023 to Present

Major depressive disorder, or depression, is among the leading causes of disability globally. Despite being a large public health challenge, depression remains difficult to treat as the underlying biology is still unknown and the currently available treatments are limited in effectiveness. This experiment was to test the efficacy of the drug LM11A-31, which works on the signaling pathway of proneurotrophin-p75NTR, a pathway that is not targeted by any currently used antidepressants. Male mice underwent a repeated forced swim, with all the mice receiving saline the first two days and then half the mice receiving saline and half receiving LM11A-31 before …

Evaluating The Effects Of Ketamine On Cognitive Flexibility In Rats Using A Probabilistic Reversal Learning Task, Anthony N. Nist

All Graduate Theses and Dissertations, Fall 2023 to Present

Depression is one of the most debilitating and widespread mental health conditions in the world today. Drugs that are traditionally prescribed to combat depression are flawed in several ways, and because of this, new treatments are needed. One drug that seems capable of overcoming the limitations of traditional antidepressants is ketamine. In clinical research, a single dose of ketamine can significantly reduce symptoms of depression quickly, its effects may last for weeks to months, and its side effects appear to be limited and relatively harmless. However, clinical research is ongoing, and more research is needed to fully understand ketamine's beneficial …

Finding Their "Why": Examining The Development Of Sense Of Purpose During The University Years And Its Role In Student Well-Being, Michael Q. King

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Nearly 20 million students were expected to be enrolled for college or university studies during the 2020-2021 academic year. These institutions often advertise to prospective students that, in addition to advancing their education, they will discover their purpose. Given previous work and current interest in sense of purpose, additional attention on sense of purpose in the university setting is worthwhile. In addition, as many university stakeholders are concerned about an ongoing mental health crisis, a further examination into a developmental construct (i.e. sense of purpose) thought to provide a “sheltering fortress in a world of constant threat” seems …

Storytelling To Promote Mental Health: A Conceptual Analysis And Application With Acceptance And Commitment Therapy For Depression, Carter H. Davis

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Mental health treatments can be delivered in many ways. One approach is to use storytelling to communicate healthy practices. While societies across the world have engaged in storytelling for thousands of years, these practices have been used less in the mental health field. The aim of this project was to study the overlap between the areas of mental health and storytelling. We also tested how a storytelling-based mental health treatment could help solve a particular clinical problem. In this case, the problem of people who receive inadequate help for managing depression through medication alone.

We examined one particular mental health …

Toddler Internalizing And Externalizing Problem Behaviors And Child Care Provider Mental Health, Danielle M. Jensen Egan

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Caregiver depression, particularly maternal depression, has repeatedly been shown to be a risk factor for the development of problem behaviors in young children. Problem behaviors fit within two categories: internalizing and externalizing. Externalizing behaviors include peer aggression, defiance, and impulsivity. Internalizing behaviors include generalized anxiety, withdrawal, separation distress, depression, and inhibition to novelty.

Gaps still exist in the research regarding the mental health of other caregivers that directly interact with children’s lives. Increasingly more children spend a great deal of time in child care settings. Less is known about child care provider stress and depression in relation to toddler problem …

Risk Factors For Early And Late Onset Depression And Subsequent Risk For Alzheimer's Disease And Related Dementias In An Older Adult Population, Jordan Kugler

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The Cache County Study on Memory in Aging (CCSMA) was a research study that followed 5092 participants aged 65 or older over the course of 12 years, examining risk and protective factors for dementia. One of these factors was depression history, which has evidence for a connection with dementia, such that those with a history of depression are more likely to develop dementia later in life. However, the existing literature has yet to examine sex differences, genetic and psychosocial factors that contribute to earlier or later onset of depression and how these factors in turn might later increase risk for …

The Effects Of Ethnic Identity And Family Obligations On Somatic Symptoms Among Latinx Emerging Adults, Jazmin Lara

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Somatic symptoms have been associated with psychological distress across different cultures and are used to diagnose depressive and anxiety disorders in the U.S. Across cultures, individuals with internalizing disorders may present with somatic symptoms outside of the diagnostic criteria, emphasizing the importance of these physical concerns. For example, Latinxs tend to endorse more somatic symptoms than White Americans, suggesting that different cultural aspects may contribute to the higher endorsement of somatic symptoms among Latinxs. However, not many studies have examined specific sociocultural factors that may be influencing somatic symptom report. This is especially true among emerging adults who are in …

Bibliotherapy For Depression: Evaluating Cognitive Behavioral Therapy And Acceptance And Commitment Therapy Approaches And Examining The Role Of Client Choice, Carter H. Davis

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

An alarming number of college students suffer from depression, which is often accompanied by struggles with anxiety and feeling inadequate compared to others (i.e., stigma). Seeing a counselor in person is challenging for many students due to wait times or feeling embarrassed or shameful. Using self-help books may be a helpful alternative for depressed students, but these books are not often tested in formal studies, and getting students to use self-help books over time is also difficult. Therefore, this study examined whether self-help books accessed online could help students with depression. We tested two books which use different approaches to …

Comparison Of Public Mental Health Stigma In Youth, Desiree A. Clarke

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The present study looked at mental health stigma in youth. Mental health stigma is devaluing, disgracing and disfavoring individuals with mental illness. Participants aged 11-14 completed a measure to rate their stigmatizing beliefs toward peers with either ADHD, depression, or asthma. Their ratings were compared for significance between genders and for the three different conditions: ADHD, depression, and asthma. Significant differences were found between the stigma ratings for asthma, depression and ADHD. ADHD had significantly higher stigma ratings than asthma, and depression had significantly higher stigma ratings than ADHD (on some, but not all, areas rated) and had consistently higher …

Depression Mediates The Association Of Disordered Eating Behaviors And Sexual Function In Female Service Members And Veterans, Whitney S. Livingston

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Poor sexual function is comprised of diminished sexual desire and arousal, presence of sexual pain, inability to reach orgasm, and low satisfaction. Worse sexual function is associated with disordered eating behavior; however, the mechanism through which this association exists remains unclear. Theory of sexual function suggests that depression mediates the association of disordered eating behaviors and poor sexual function in female service members and veterans, but this has yet to be tested empirically. The purpose of the current study was to examine whether depression mediated the association of disordered eating behaviors and sexual dysfunction.

Participants (N=511) were partnered …

Maternal Depression In The United States: A Geographic Comparison Between Geographic Regions And Rurality, Samantha J. Patterson

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Health disparities exist between rural and urban areas but geographic comparisons of mental health are less studied and conclusive. Maternal depression has not been examined by region or rurality in the United States but might be influenced by geographic locations due to the variance of social support and healthcare available in some locations compared to others. The research focuses on (1) whether rurality increases a mother’s risk of experiencing depression and (2) if region impacts a mother’s risk of depression. I used the NESARC-III data that included three general depressive disorders: major depressive episode, major depressive disorder, and dysthymia. Regions …

The Impact Of High School Extracurriculars: Similarities And Differences In Sense Of Community Among Competitive, Performance, And Participatory Activities, Erica M. Hawvermale

Undergraduate Honors Capstone Projects

Extant research links high sense of community in adolescence to adaptive outcomes such as enhanced motivation, self-efficacy, and coping ability (Battistich, Solomon, Watson, & Schaps, 1997; Vieno, Perkins, Smith, & Santinello, 2005; Henry & Slater, 2007), as well as reduced stress, anxiety, and depression (Chipuer, Bramston, & Pretty, 2002). In light of these findings, the present study was designed to assess the relationship between high school students’ participation in extracurricular activities and their perceptions of sense of community, enjoyment, and commitment, as well as the aspects of these organizations that help to facilitate feelings of community. Study 1 participants (N= …

Utilizing Act Daily As A Self-Guided Mobile App Intervention For Depression And Anxiety In A College Counseling Center, Jack A. Haeger

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

College counseling centers (CCCs) have experienced funding and staffing setbacks in recent years, resulting in higher caseloads, counselor burnout, and bloated waitlists. Mobile Health (mHealth) interventions may offer a cost-effective and innovative solution. The authors developed ACT Daily, a prototype mHealth app based in Acceptance and Commitment Therapy (ACT). This study examined the feasibility and possible efficacy of ACT Daily as a brief intervention for individuals placed on CCC waitlists.

A sample of 11 depressed/anxious clients waitlisted at a local CCC enrolled in the study, which followed a pre-post, open trial design. Participants received a brief online training that covered …

Latent Classes Of Self-Reported Adolescent Depression In A Clinical In-Patient Population, Jonathan F. Doti

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The depressive disorders are among the most common mental health problems with substantial financial and quality-of-life costs. Depression has generated considerable debate as to the underlying structure/taxonomy and continues to be frequently debated. Adolescents who meet diagnostic criteria for major depressive disorder often experience anxiety (and vice versa). Therefore, understanding the underlying structure of depression as well as the co-occurrence of anxiety in a population of adolescents adds to our conceptual understanding of these disorders and facilitates treatment clarity.

This investigation sought to investigate the following research questions for adolescents’ self-reported symptoms of depression, and self-reported symptoms of depression and …

The Relationship Of Outdoor Recreation And Gardening With Depression Among Individuals With Disabilities, Justin Floyd Wilson

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Activities involving natural environments have positive psychological impacts on participants. Both outdoor recreation and gardening have been shown to reduce feelings of depression. However, the effects of these activities on the depression levels of individuals with disabilities have not yet been studied. In order to better understand the relationship between these activities and depression among individuals with disabilities, two separate studies were conducted.

The first study seeks to better understand the relationship between outdoor recreation participation and depression among Montana residents with disabilities using publicly available Behavioral Risk Factor Surveillance System (BRFSS) data. It hypothesizes that depression would be negatively …

The Relationship Of Acculturation And Acculturative Stress In Latina/O Youths’ Psychosocial Functioning, Marsha Tafoya

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

This study was conducted to better understand how acculturation and acculturative stress are related to self-esteem, depression, substance use, and substance use problems in 206 Latina/o youth. Acculturation is the social and psychological process of change that occurs when an individual or group comes in contact with a different culture. The acculturation process can be positive, improving one’s life chances in the new culture, or it could be negative due to the challenging nature of change and adaptation to new cultural and social expectations. This difficulty creates a type of stress, called acculturative stress that has been found to be …

The Male Gender Role And Depression, Tom Liljegren

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

Although depression is a common mental health disorder, less research has been devoted to men's experience with depression compared to women's experiences. Although men may exhibit similar patterns of depression as women, men often have unique pattern of exhibiting depression characterized by substance abuse, irritability, aggression, and interpersonal conflict. The paper presents a review of the relevant literature on male depression and, in particular, how it is potentially affected by male gender role factors. Biological, psychological, social, and artifact theories have been proposed to explain gender differences in how depression is expressed. It is hypothesized that the male gender role …

The Ability Of The Coping Competence Questionnaire To Predict Resilience Against Learned Helplessness Among Undergraduate College Students: An Experimental Study, Cindy L. Ollis

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The Coping Competence Questionnaire (CCQ), based on the reformulated learned helplessness theory, was designed to assess a general stress resistance versus a propensity towards learned helplessness with a brief, 12-item self-report questionnaire. In this study the CCQ was administered to 247 undergraduate students, who were then paired, in groups of around 24 at a time, and then randomly assigned to either success or failure conditions on the computer game TetraVex. Mood was pretested using the Profile of Mood States (POMS) depression subscale; the experimental condition, success or failure at TetraVex was conducted; then outcome measures including 20 five letter anagrams …

Depression Detection In Hospitalized Cardiac Patients, Martine S. Geddes

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Depression has been shown to increase an individual's risk for heart disease. Despite this finding, physicians are not identifying depression in their hospitalized cardiac patients. This study looked at hospitalized cardiac patients and determined whether their physicians were identifying depression in those that scored ≥ 5 on the PHQ-9 depression inventory. Methods included assessing patient depression during their stay at an intensive care unit using the PHQ-9. Those patients scoring ≥ 5 were determined as depressed. Chart audits were performed after the patient discharged from the hospital to discover whether physicians were identifying these patients as depressed. The results showed …

Taste Sensitivity To 6-N-Propylthiouracil (Prop) As A Biological Marker For Vulnerability To Stress In Mothers And Children, Deann Jones

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Some people are genetically more vulnerable to stress than others, leading them towards poorer outcomes following stressful events. Mothers' vulnerability to stress may, in turn, influence their children, leading their children towards poor outcomes as well. A biological marker of vulnerability to stress may indicate mothers who are at greater risk for experiencing parenting stress, depression, and less support of the infant's emotional development, and infants who are at greater risk for development of poor emotion regulation and behavior problems. Taste sensitivity to propylthiouracil (PROP) is proposed as a biological marker of stress vulnerability in mothers and children. This research …

Technologically Assisted Intervention (Tai): Are Clients Satisfied With Online Therapy?, Jennifer A. Morrow

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

This study examined the level of satisfaction reported by participants of a technologically assisted intervention study (TAI). TAI is a type of teletherapy done through online, live video conferencing. Satisfaction was examined at three different time points, post therapy, 3-months post therapy, and 6-months post therapy. Analyses examined if there were any changes in reported satisfaction over the three time periods. Participants received cognitive behavioral therapy (CBT) targeted at reducing symptoms of mild to moderately severe depression. A satisfaction measure was developed for this study, and included quantitative and qualitative items which were analyzed to determine participants' level of satisfaction. …

Therapeutic Processes In A Cognitive-Behavioral Treatment For Depressed Adolescents With Inflammatory Bowel Disease, Meredith Brent

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Youth with inflammatory bowel disease (IBD) have higher rates of depression than healthy youth. A cognitive-behavioral treatment, primary and secondary control enhancement training-physical illness (PASCET-PI), for depressed adolescents with IBD was associated with reductions in depressive symptoms. The purpose of this study was to examine the salience of nonspecific processes (factors inherent in any human relationship) and specific processes (factors related to therapy content) during PASCET-PI sessions and their association with improvements in psychological functioning.

Participants included 10 adolescent patients with IBD with mean illness duration of 31.9 months. At intake, eight participants qualified for a diagnosis of major depressive …

The Relation Between Religiosity And Late-Life Depression In A Community Sample Of Members Of The Church Of Jesus Christ Of Latter-Day Saints, Lynn Marie Franklin

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

A secondary analysis of extant data from The Cache County Study on Memory Health and Aging (CCSMHA), this study examines the association between religiosity and new-onset depression between baseline and 4-year follow-up interviews in a sample of 1,439 community-dwelling elderly members of The Church of Jesus Christ of Latter-day Saints (LDS), aged 65 to 100. Logistic regression models found that church attendance, voluntarism in religious groups, and direct experiences of God occurring more often than weekly were (statistically and practically) significantly associated with lower depression risk. No evidence was found for moderator effects of gender or prior depression history; however, …

Identification Of Factors Affecting Susceptibility To Depression And Influencing Quality Of Life In Adult Cystic Fibrosis Patients Based On Age-At-Diagnosis, Marlene Israelsen

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Approximately 10% of cystic fibrosis (CF) cases remain undiagnosed until age 18 or later and medical professionals are still unclear about the needs of these individuals. Adults with CF must either adapt to life with a chronic disease or transition into adulthood with CF. The purpose of this study was to address the impact of age-at-diagnosis on quality of life in a CF adult population.

The psychological functioning of 21 adult CF patients (seven adult-diagnosed (AD) and 14 pediatric-diagnosed (PD)) was assessed using the Beck Depression Index (BDI)-II. A descriptive review of demographic and clinical data, which included an assessment …

Parents Of Children With Severe Disabilities: Parental Stress, Depression, And The Marital Relationship, Melinda W. Christensen

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

This paper provides an overview of parental stress and depression in families with children diagnosed with severe cognitive disabilities. Previous research on parents with children with disabilities was reviewed. Studies were selected from peer-reviewed journal articles that specifically included children with an IQ below 70 or a noted cognitive impairment of a severe degree. Children in the study had to be living at home and below the age of 21. Significant levels of stress and depression were not found consistently in the studies reviewed. Parents of children with disabilities did report levels of stress and depression above the control groups …

Testing Models Of Depression And Paranoia In Men And Women: The Role Of Cognitive Style, Guilt, Shame, And Defense Mechanisms, Chad Sombke

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Gender differences in psychopathology have long been of interest in the fields of clinical, developmental, and personality psychology. Lewis proposed two models to explain the emergence of the development of gender differences in depression and paranoia. Lewis stated that gender differences in depression and paranoia can be traced to corresponding gender differences in cognitive style, guilt-proneness, shame-proneness, and the use of specific defense mechanisms. Although research evidence has validated certain components of these two models, neither model has ever been tested in its entirety. This research project intended to test Lewis's models in their entirety by utilizing structural equation modeling. …

Factor Structure Of The Anorexia Bulimia Inventory, Anne C. Dobmeyer

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The Anorexia Bulimia Inventory, a recently developed self-report questionnaire for the assessment of eating disorders, addresses two major limitations found in existing self-report eating disorder inventories. First, it comprehensively assesses the diagnostic symptoms of both bulimia and anorexia nervosa; and second, it assesses the frequently cooccurring problem areas (e.g., depression, anergia) that may be targeted in treatment planning for eating disorders. Although initial research on the psychometrics of the instrument appears promising, no research has yet investigated its factor structure. Therefore, the goal of the present study was to investigate the factor structure of the Anorexia Bulimia Inventory.

Principal axis …

Gender And Depression: Analysis Of The Effects Of Sex Roles, Sex-Role Self-Discrepancy, And Attributional Style, Scott V. Cutler

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The purpose of this study was to examine the influence of attributional style, sex roles, and sex-role self-discrepancy in the relationship between gender and depression. Epidemiological studies report a higher incidence of depression among women then men (approximately 2:1). Among the various theories suggested to explain this gender difference, sex roles, attributional style, and self-discrepancy have been conceived as possible explanations. The relationship between gender and depression may be better understood through examining the possible contribution of these three independent variables.

To examine these theories, a sample of 130 subjects was drawn from clients at the USU Counseling Center, the …

Personality Factors Associated With Negative Affect: Application Of The "Big Five" Taxonomy To Depression And Anxiety, Kent W. Anderson

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The purpose of this study was to examine the patterns and discriminant utility of the five-factor model of personality ("Big Five," consisting of neuroticism, extraversion, openness to experience, agreeableness, and conscientiousness factors) with depressed and anxious outpatients.

One hundred two outpatients seeking services at a community mental health center in a small western community participated in the study. Subjects were 41 clients with a depressive disorder, 31 with an anxiety disorder, and 30 in a mixed clinical control group. Subjects completed the Neuroticism-Extraversion-Openness to Experience Five-Factor Inventory (NEO-FFI).

Results indicate that both depressed and anxious clients score in the "very …

The Role Of Gender Differences In The Relationship Between Guilt- And Shame-Proneness And Depressive Symptomatology, Julie Bingham Shiffler

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The purpose of this study was to examine the role played by gender in the relationship between the degree of depressive symptomatology and levels of adaptive guilt-, maladaptive guilt-, and shame-proneness in a college population. A measure of depressive symptomatology (the Beck Depression Inventory) and a measure of guilt- and shame-proneness (the Self-Conscious Affect and Attribution Inventory - Revised) were administered to 299 college students (113 males and 186 females). Females reported higher total levels of depressive symptomatology than males. Statistically significant gender differences were found for nine BDI items. Females also had higher levels of adaptive guilt-, maladaptive guilt-, …