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Genetic And Environmental Interactions On Schizophrenia-Like Phenotypes In Chl1 Deficient Mice, J. Daniel Obray
Genetic And Environmental Interactions On Schizophrenia-Like Phenotypes In Chl1 Deficient Mice, J. Daniel Obray
Undergraduate Honors Capstone Projects
Schizophrenia is a debilitating disorder which is often characterized by dysregulation of the processing of sensory information. Schizophrenia has been shown to have a strong genetic component, as well as a strong environmental component. As such, a number of hypotheses such as the diathesis stress hypothesis have been developed to explain the etiology of schizophrenia. As most of these theories attempt to account for a genetic and an environmental factor, they are often viewed as double-hit models of schizophrenia. Several theories have emerged as potential explanations for the symptoms of schizophrenia. The dopamine hypothesis suggests that the basal level of …
Identification Of Key Genes Required For Abiotic Stress Response In Arabidopsis Thaliana, Saori Endo
Identification Of Key Genes Required For Abiotic Stress Response In Arabidopsis Thaliana, Saori Endo
Undergraduate Honors Capstone Projects
To identify key genes that are required for stress response, a reverse genetics approach was taken to manipulate expression of candidate genes in plants. In this project, two potential regulatory genes which were originally identified as stress-responsive genes from a microarray experiment in Arabidopsis were examined for their roles in stress tolerance. Over-expression of gene A, which was up-regulated under stress conditions based on the array data, caused earlier flowering and improved plant growth under salinity and dehydration stress conditions at the seedling stage. Over-expression of gene B, which was down-regulated under stress conditions based on the array data, resulted …
Single Nucleotide Polymorphism (Snp) Analysis Of Tumor Necrosis Factor (Tnf)-Α In Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections (Pandas) Subjects, Corinna Wilhelmina Vonniederhausern
Single Nucleotide Polymorphism (Snp) Analysis Of Tumor Necrosis Factor (Tnf)-Α In Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections (Pandas) Subjects, Corinna Wilhelmina Vonniederhausern
Undergraduate Honors Capstone Projects
In an ongoing research project, the Center for Persons with Disabilities at Utah State University, in collaboration with Dr. Susan E. Swedo at the National Institute of Mental Health, is evaluating genetic factors affecting the development of PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections). PANDAS is manifested in a group of prepubertal children who develop obsessive-compulsive disorder (OCD) following infection with Group A beta-hemolytic Streptococcal (GABHS) bacteria. We are assessing single nucleotide polymorphisms (SNPs) in the promoter region of tumor necrosis factor (TNF)-α and other cytokines known to be important in autoimmune diseases.
Obesity: Environment Vs. Genetics, Kammi Marie Reeder Hansen
Obesity: Environment Vs. Genetics, Kammi Marie Reeder Hansen
Undergraduate Honors Capstone Projects
The prevalence of overweight and obese individuals is rising. Between 1980 and 1990 there was an 8% increase in the prevalence of obesity. Obesity is associated with many diseases such as hypertension, type 2 diabetes, heart disease and cancer. Over $39 billion dollars is spent annually on the illnesses associated with obesity. Our American culture has been blamed for the rise in obesity, yet there are obviously many people living in the American culture that are not obese. Researchers have turned to genetics to explain this phenomenon. This article will examine the many environmental factors that contribute to obesity and …