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Let Go And Let God: An Ethnographic Study Of Overeaters Anonymous, Subjectivity, And Extreme Eating Distress, Abby Forster May 2023

Let Go And Let God: An Ethnographic Study Of Overeaters Anonymous, Subjectivity, And Extreme Eating Distress, Abby Forster

Theses and Dissertations

Academic discussions regarding eating disorders have been dominated by two frameworks: biomedical and feminist. While the former explains eating disorders as a product of individual pathology, the latter asserts the cause is culture. An aspect of culture that is often suggested is neoliberalism. This ethnographic study utilizes the term “eating distress” to acknowledge the localized idioms that occur outside of the bounds of biomedical settings. The research documents the experiences of many members of Overeaters Anonymous dealing with eating distress within a social context in which their body types are stigmatized. The dissertation examines the relationship between subjectivity, Overeaters Anonymous, …


Masculinity And Men’S Health Attitudes Toward Consideration Of Weight-Loss Surgery, Karaline Fusco Aug 2022

Masculinity And Men’S Health Attitudes Toward Consideration Of Weight-Loss Surgery, Karaline Fusco

Theses and Dissertations

The rise in obesity across the United States has led to greater educational outreach, considerable research, and medical interventions aimed at decreasing the rate of obesity-related health diseases. But are these interventions reaching everyone? Despite men and women having equivalent rates of obesity, only 20% of weight-loss surgery patients are men. While men have an average life expectancy that is 5 years less than women and are twice as likely than women to have heart disease, men also underutilize healthcare services. Given these factors, this research explored men’s health beliefs, conformity to male norms, and receptivity to weight-loss surgery. This …


Obesity Suppresses Pigment Epithelium-Derived Factor And Alters Pro-Tumorigenic Signaling Pathways In Prostate Cancer, Nizar Ahmed Khamjan Aug 2019

Obesity Suppresses Pigment Epithelium-Derived Factor And Alters Pro-Tumorigenic Signaling Pathways In Prostate Cancer, Nizar Ahmed Khamjan

Theses and Dissertations

Background: Pigment epithelium-derived factor (PEDF), a multifunctional protein, is a potent tumor suppressor and anti-angiogenic factor. PEDF has been identified as a novel regulator of lipid metabolism via binding and activating adipose triglyceride lipase, which stimulates lipolytic pathways. PEDF-deficient mice develop prostatic hyperplasia that progresses to cancer when these mice are fed a high fat diet (HFD). PEDF expression is decreased in prostate cancer (PCa) patient tissues. Conversely, PEDF treatment inhibits PCa growth in mouse models. Recently, our lab has demonstrated that excess oleic acid (OA) treatment, an in vitro obesity model, suppresses secreted PEDF expression in PCa cell lines …


Health, Wellness, And The Health Care Experiences Of Female Adolescents Living With Increased Weight, April L. Yerges Dec 2018

Health, Wellness, And The Health Care Experiences Of Female Adolescents Living With Increased Weight, April L. Yerges

Theses and Dissertations

Clinic-based health care encounters (HCEs) remain a beneficial setting for early assessment, identification and treatment of overweight in adolescents. The purpose of this study is to describe how female adolescents who are obese or overweight perceive the health care encounter with a particular focus on obesity. Using a qualitative design, a purposive sample of 28 English speaking female adolescents, 13–19 years of age, who were overweight or obese, participated in in-depth interviews. Five themes emerged from the thematic analysis: Mental and physical wellness, The impact of weight, Cause I’m a teenager, Talking about weight affects me, and Help me instead …


Motivators And Barriers To Health Behaviors In African American Women, Teresa M. Depratt Aug 2018

Motivators And Barriers To Health Behaviors In African American Women, Teresa M. Depratt

Theses and Dissertations

Women who identify as African American are at particularly high risk of developing obesity and associated health concerns such as diabetes, heart disease, and cancers. Eating healthfully and engaging in a minimal amount of physical activity are known to be both preventative and curative. Based on review of research, this study investigated potential constructs of Motivators and Barriers to health-supporting behaviors as they are perceived in African American women. The study also constructed a novel scale, Motivators and Barriers to Health Behaviors (MBHB), which intended to capture some constructs of each domain via two surveys. Also of interest was if …


Nurses' Reactions To Patient Weight: Effects On Clinical Decisions, Heidi M. Pfeiffer May 2017

Nurses' Reactions To Patient Weight: Effects On Clinical Decisions, Heidi M. Pfeiffer

Theses and Dissertations

In previous research, a variety of health care providers have expressed some degree of negative attitudes toward caring for obese patients. However, little is known about whether these negative attitudes lead to differential care. This study focused on the clinical decision-making of nurses, who are under-represented in this type of research despite their central and sustained role in patients’ care experiences. In an anonymous online survey, 256 nurses responded to clinical vignettes about a hypothetical patient depicted in a photograph. The patient’s appearance was altered to appear normal-weight or obese, for each of two different models per sex, utilizing a …


Antioxidant Function Of Pigment Epithelium Derived Factor In Adipose Tissue, The Prostate, And Prostate Cancer, Lyndsey Sandra Crump Aug 2015

Antioxidant Function Of Pigment Epithelium Derived Factor In Adipose Tissue, The Prostate, And Prostate Cancer, Lyndsey Sandra Crump

Theses and Dissertations

Aggressive prostate cancer (PCa) is positively correlated with obesity and a high fat diet, suggesting that dysregulated lipid metabolism promotes PCa progression. Pigment epithelium-derived factor (PEDF) regulates angiogenesis, lipid metabolism, and has antioxidant function in other cell types. In the prostate, PEDF inhibits angiogenesis, and its expression is decreased in PCa. However, PEDF’s role in regulating lipid metabolism and oxidative stress levels has not been investigated, and, as such, was the goal of the present study. Oxidative stress levels were evaluated in vivo and ex vivo in prostate and adipose tissues from wildtype (C56Bl/6J) and PEDF knockout (KO) mice. In …


Metformin-Induced Pedf Expression Regulates Cell Proliferation And Lipid Metabolism In Prostate Cancer Cells, Miguel Angel Tolentino Aug 2013

Metformin-Induced Pedf Expression Regulates Cell Proliferation And Lipid Metabolism In Prostate Cancer Cells, Miguel Angel Tolentino

Theses and Dissertations

Prostate cancer (PCa) is one of the most common cancers in American males. A high fat diet and obesity accelerate PCa progression and increase the 1risk of death from disease. Epidemiological studies have indicated that PCa patients with type 2 diabetes have higher mortality rates than PCa patients without diabetes. Type 2 diabetics who are on metformin, a drug to control blood sugar levels, show a delay in PCa progression in comparison with PCa patients with type 2 diabetes who are not on metformin. It has been proposed that metformin inhibits proliferation via activation of AMP-activated protein kinase (AMPK) or …