Digital Commons Network^™

Student Perceptions Of Community-Engaged Scholarship Courses: Developing A Sociolinguistic Corpus On The U.S.–Mexico Border, Katherine Christoffersen, Aubrey Villanueva, Ryan M. Bessett

Writing and Language Studies Faculty Publications and Presentations

The well-documented benefits of community engagement experiences have resulted in its incorporation across a wide variety of disciplines, from health care (Alexander et al., 2020) to aviation science (Belt & Sweetman, 2021) to statistics (Schanz & Giles, 2021). The field of sociolinguistics is no exception with plentiful examples of community-engaged scholarship (CES) or “research of mutual benefit to community and academic interests” (Delugan et al., 2014, p. 155). One way that linguistics and language courses have integrated CES is through the development of community-based sociolinguistic corpora or collections of informal interviews with community members. In these courses, students are trained …

Anti-Apostatic Feeding Behavior In Two Species Of Assassin Bug, The White-Spotted Assassin Bug Platymeris Biguttatus And Red-Spotted Assassin Bug Platymeris Rhadamanthus (Hemiptera: Reduviidae), Julia H. Potocnjak, Christopher Vitek

School of Integrative Biological and Chemical Sciences Faculty Publications and Presentations

Predator-prey relationships are a driving force when examining community ecology. One question in predator-prey interactions is how a predator may respond to novel prey phenotypes, a form of frequency dependent prey selection. A predator may selectively target or avoid the novel prey, a behavior referred to as anti-apostatic or apostatic selection respectively. We examined apostatic prey selection by observing feeding behavior in two species of assassin bugs (Hemiptera: Reduviidae), the white-spotted assassin bug (Platymeris biguttatus) and the red-spotted assassin bug (Platymeris rhadamanthus) which were fed unmodified and modified (novel) phenotypes of Turkistan cockroaches, Blatta lateralis (Blattodea: …

Bridging Bone Health: Osteoporosis Disparities In The Rio Grande Valley, Ryan P. Bialaszewski, John M. Gaddis, Blake Martin, Philippe J. Dentino, John Ronnau

School of Medicine Publications and Presentations

Introduction: Osteoporosis is characterized by decreased bone mass and decreased bone quality, leading to increased bone fragility and risk of fractures. The number of fractures due to osteoporosis is projected to increase to over three million by the year 2025 and cost $25.3 billion annually. It ranks highly among diseases that cause patients to become bedridden with serious complications and reduced quality of life. Additionally, osteoporosis disproportionately affects Hispanics, which comprise most of the Rio Grande Valley (RGV) population. Therefore, our primary objective was to determine the prevalence of osteoporosis within the RGV. Additionally, we had secondary objectives to determine …

Dementia And Stroke Risk Associated With Brain Artery Luminal Diameters, Jesus D. Melgarejo, Kursat Gurel, Minghua Liu, Bonnie Levin, Mitchell S.V. Elkind, M. Kamran Ikram, M. Arfan Ikram, Fabrice Crivello, Christophe Tzourio, Zhen-Yu Zhang

School of Medicine Publications and Presentations

Background: It is unclear whether brain artery diameters measured on conventional T2-weighted brain MRI images relate to dementia and stroke outcomes across distinct populations. We aimed this study to evaluate the association of T2-weighted brain artery luminal diameters with dementia and stroke in three distinct population‑based studies.

Methods: Three longitudinal population-based studies with 8420 adults >40 years old (Northern Manhattan Study [NOMAS] from the United States, and the Rotterdam Study [RS], from the Netherlands, and Three-City, from France) with brain MRI scans obtained between 1999 and 2015. The median follow-up time for clinical events ranged between 7 and …

Cognitive Sequealae Of Covid-19 Is Not Predicted By Sars-Cov-2 Variants, Gabriel A. De Erausquin, Jorge Igor Zwir, Heather Snyder, Gabriela Gonzalez-Aleman, Hernan P. Zamponi, Mariana Figueredo-Aguiar, Emiliano Fumagalli, John Blangero, Agustín Yécora,, Fabiana Vaca, Gabriela Kukoc

School of Medicine Publications and Presentations

Background: The long term sequelae of COVID-19 in older adults are only beginning to be clarified, and its predictors and underlying molecular mechanisms may shed light on the relationship between viral infections and Alzheimer's disease and related dementia.

Method: A prospective cohort of 874 older adult Amerindians from Argentina with COVID-19 illness confirmed by PCR of nasal swabs as well as controls, was established during the first year of the COVID-19 pandemic. We obtained data on the severity of the acute illness, as well as extensive neuropsychiatric and cognitive assessments, neurological exams (including quantitative hyposmia/anosmia), plasma for biomarkers and preliminary …

An Innovative Model Using Promotores Or Community Health Workers For Home Based Dementia Care, Neela K. Patel, Cynthia De La Garza- Parker, Angelica Davila, Noe Garza, Monica Goss, Claudia L. Satizabal, Gabriel A. De Erausquin, Gladys E. Maestre, Sudha Seshadri

School of Medicine Publications and Presentations

Background: Health disparities and issues with trust building and relationship building are prominent in Hispanic and underserved populations in south Texas. Community health workers can play a bridging role with underserved communities and may be essential in improving the quality and value of health care. The Texas Health and Human Services Commission certifies the training Community Health Workers under the label of “promotores”.

Method: Community health workers were integrated into the primary health care team to serve as a bridge between patient/caregiver dyads and the health care team.

Result: Community health workers (CHWs) connected patients to social determinants …

Lower Locus Coeruleus Integrity In Older Covid-19 Survivors: Initial Findings From An International 7t Mri Consortium, Heidi I.L. Jacobs, Tamer Ibrahim, Farhaan S. Vahidy, Timothy D. Girard, Akram A. Hosseini, Salem Alkateeb, Richard Bowtell, Gowland Penny, Mohamad Habes, Valentina R. Garbarino

School of Medicine Publications and Presentations

Background: The SARS-CoV-2 coronavirus has been associated with structural brain changes, consistent with its neurological manifestations. Recent studies showed a specific predilection for brainstem glial activation and hypometabolism, possibly indicating involvement of the locus coeruleus. The locus coeruleus (LC) modulates many cognitive functions and behaviors and its norepinephrine projections regulate both immune responses and vascular reactivity. We aimed to examine differences in LC integrity between COVID-19 survivors and controls.

Method: Participants are enrolled across 3 US and 1 UK sites using harmonized cognitive and 7T MR-imaging protocols. Here, we analyzed data from 18 participants enrolled at Houston Methodist (12 COVID-19 …

Elevated Amyloid-Β And Tau Levels In The Brain Are Associated With A Reduced Abundance Of Neuroprotective Gut Bacteria, Yannick Joel Wadop Ngouongo, Jazmyn A. S. Muhammad, Tiffany F. Kautz, Claudia Satizabal, Jayandra Jung Himali, Sudha Seshadri, Bernard Fongang

School of Medicine Publications and Presentations

Background: Recent research suggests that differences in the gut microbiome composition may contribute to the pathogenesis of neurological disorders, including Alzheimer's disease (AD). Animal studies have shown that fecal microbiota transplantation reduces amyloid plaques in mouse AD models. However, whether the buildup of Aβ and tau deposits in the brain are associated with shifts in the human gut microbiota composition is understudied.

Method: We used stool specimens and neuropathological measures from 140 middle-aged individuals (Table 1: mean age 56, 54% Female) from the Framingham Heart Study (FHS) to assess the link between the gut microbiome composition and Aβ Positron …

Cognitive Decline Associated With Longitudinal Changes In 24-H Ambulatory Blood Pressure Variability, Jesus D. Melgarejo, Kristina P. Vatcheva, Luis J. Mena, Carlos A. Chavez, Egle Silva, Gustavo E. Calmon, Rosa P. Mavarez, Joseph H. Lee, Joseph D. Terwilliger, Gladys E. Maestre

School of Medicine Publications and Presentations

Background: Cognitive decline has been associated with variability in blood pressure (BP). However, whether the increment of the BP variability during follow-up precedes cognitive decline remains undocumented. We aimed this study to investigate cognitive decline in relation to longitudinal changes in 24-h reading-to-reading BP variability.

Methods: We conducted an observational longitudinal study that included 717 dementia-free participants from the Maracaibo Aging Study who underwent follow-up assessment in both 24-h ambulatory BP monitoring and cognitive tests between 1998 and 2015. Cognitive domains consisted of selective reminding tests (total, long-term, short-term, and recognition memory) and the Mini-Mental State Examination (MMSE). …

Exploration Of The Tumorigenic, Metabolic, And Cognitive Consequences Of Tau Protein Removal, Jennifer M. Erichsen, Valentina R. Garbarino, Anna Rodriguez, Jillian K. Lee, Justin C. Shayne, Timothy C. Orr, Miranda E. Orr

School of Medicine Publications and Presentations

Background: Tau accumulation causes tauopathies and drives cellular senescence, which can lead to inflammation, neurodegeneration, and cognitive impairment. The association between intracellular tau deposition and pathogenesis has prompted therapeutic strategies that reduce tau expression. However, tau is also critical in microtubule stabilization, synaptic plasticity, and maintaining DNA integrity. We investigated the impact of tau removal on brain cell senescence and associated neurocognitive behaviors in aged tau knockout (Mapt^0/0) and wild type control (Mapt^+/+) mice. We also assessed physical, metabolic, histological, and biochemical outcomes in Mapt^0/0 and Mapt^+/+ mice and in response to …

Poor Cognition Is Associated With Increased Abundance Of Alistipes And Decreased Abundance Of Clostridium Genera In The Gut, Jazmyn A. Muhammad, Yannick Joel Wadop Ngouongo, Sophia Ramirez, Tiffany F. Kautz, Claudia L. L. Satizabal, Jayandra Jung Himali, Sudha Seshadri, Bernard Fongang

School of Medicine Publications and Presentations

Background: Brain and gut health are intricately connected via the gut-microbiota-brain axis. Studies have shown that gut dysbiosis is associated with neurodegenerative diseases, including Alzheimer’s disease. However, how cognitive changes affects the gut microbiome structure is currently understudied. We aimed to assess the association between the gut microbiome and global cognitive scores in the Framingham Heart Study (FHS).

Method: Our sample included 1,014 participants (mean age 52, 55% female) of the third generation FHS cohort with available stool samples, cognitive assessments, and no history of dementia or stroke (Table 1).We quantified the gut microbiome composition using 16S rRNA …

Covid-19 May Have A Detrimental Impact On Sensorimotor Function, Monica Goss, Rebecca Bernal, Vibhuti N. Patel, Karl Li, Valentina R. Garbarino, Rejani R. Nair, Heather Snyder, Gabriel A. De Erausquin, Mary Ganguli, Beth E. Snitz, Timothy D. Girard

School of Medicine Publications and Presentations

Background: The long-term impact of COVID-19 on global health is still unknown. Sensorimotor biomarkers may be promising indicators of lasting effects of COVID-19. Although normal aging may cause changes in sensorimotor function, more severe changes may indicate the subsequent impacts of COVID-19 on brain health. The objective of this study was to investigate the association between COVID-19 and sensorimotor markers (grip strength, gait, and smell) in the 7T neuroCOVID consortium, which is comprised of 5 sites: The University of Texas Health Science Center at San Antonio, Houston Methodist Research Institute, The University of Pittsburgh, Massachusetts General Hospital, and Nottingham University …

Hippocampal Subfield Volumes In Covid-19: A Preliminary Multicenter Study Using 7t Mri, Salem Alkateeb, Jinghang Li, Gabriel A. De Erausquin, Monica Goss, Jayandra J. Himali, Karl Li, Rejani R. Nair, Beth E. Snitz, Gowland Penny, Valentina R. Garbarino

School of Medicine Publications and Presentations

Background: Hippocampal formation atrophy is a well-established imaging biomarker of several neurological diseases, including Alzheimer's disease, temporal lobe epilepsy, and schizophrenia. The hippocampus is divided into subfields that have different functions and vary in sensitivity to different diseases. This study investigates the potential interaction between COVID-19 and the various hippocampus subfields, which may shed light on the long-term neurological consequences of the virus.

Method: We obtained high-resolution T1-weighted (T1w) and T2-weighted (T2w) MRI images using 7T scanners located at three sites in two countries: Pittsburgh (n=14) and Texas (San Antonio and Houston) (n=40) in the USA, and Nottingham, …

Preliminary Neurocognitive Finding From A Multi-Site Study Investing Long-Term Neurological Impact Of Covid-19 Using Ultra-High Field 7 Tesla Mri-Based Neuroimaging, Jonika D. Tannous, Farhaan S. Vahidy, Riddhi Patira, Alison M. Luckey, Mitzi M. Gonzales, Akram A. Hosseini, Timothy D. Girard, Tamer Ibrahim, Heidi I.L. Jacobs, Valentina R. Garbarino

School of Medicine Publications and Presentations

Background: Globally, over six hundred million cases of SARS-CoV-2 have been confirmed. As the number of individuals in recovery rises, examining long-term neurological effects, including cognitive impairment and cerebral microstructural and microvascular changes, has become paramount., We present preliminary cognitive findings from an ongoing multi-site study investigating the long-term neurological impacts of COVID-19 using 7 Tesla MRI-based neuroimaging.

Methods: Across 3 US and 1 UK sites, we identified adult (>=18) COVID-19 survivors (CS) and healthy controls (HC) without significant pre-existing medical, neurological, or psychiatric illness. Using the National Alzheimer’s Coordinating Center (NACC) Uniform Data Set (UDS-3) battery …

Point-Of-Care Ultrasound For The Diagnosis Of Frequent Cardiovascular Diseases: A Review, Ernesto Calderon Martinez, Edna Diarte, Diana Othon, Leonardo Rodriguez Reyes, Daniel A. Aguirre Cano, Carolina Cantu Navarro, Maria G. Ycaza, David Arriaga Escamilla, Jinal Choudhari, George Michel

School of Medicine Publications and Presentations

Point-of-care ultrasound (POCUS) has emerged as an indispensable diagnostic tool in cardiology, particularly within the emergency department. This narrative synthesis provides a comprehensive exploration of POCUS applications in cardiovascular diseases, elucidating its multifaceted roles and addressing challenges. The review delves into the technical attributes of POCUS, emphasizing its noninvasive nature, radiation-free qualities, and suitability for non-radiologists. It navigates through educational strategies, stressing the importance of structured programs for the seamless integration of POCUS into clinical practice. Highlighting its efficacy, the synthesis discusses POCUS applications in various scenarios such as dyspnea, chest pain, cardiac arrest, aortic dissection, pericardial effusion, and pulmonary …

Effects Of Mars Global Simulant (Mgs-1) On Growth And Physiology Of Sweet Potato: A Space Model Plant, Karthik Chinnannan, Prapooja Somagattu, Hyndavi Yammanuru, Padma Nimmakayala, Manohar Chakrabarti, Umesh K. Reddy

School of Integrative Biological and Chemical Sciences Faculty Publications and Presentations

Growing food autonomously on Mars is challenging due to the Martian soil's low nutrient content and high salinity. Understanding how plants adapt and evaluating their nutritional attributes are pivotal for sustained Mars missions. This research delves into the regeneration, stress tolerance, and dietary metrics of sweet potato (Ipomoea batatas) across different Mars Global Simulant (MGS-1) concentrations (0, 25, 50, and 75%). In our greenhouse experiment, 75% MGS-1 concentration significantly inhibited sweet potato growth, storage root biomass, and chlorophyll content. This concentration also elevated the plant tissues' H2O2, proline, and ascorbic acid levels. Higher MGS-1 exposures (50 and 75%) …

Where I Am From Matters: Factors Influencing Behavioral And Emotional Changes In Autistic Individuals During Covid-19 In Latin America, María Cecilia Montenegro, Ana C. Ramírez, Juventino Hernandez Rodriguez, Bianca T. Villalobos, Gabriela Garrido, Cecilia Amigo, Daniel Valdez, Natalia Barrios, Sebastián Cukier, Cecilia Montiel-Nava

Psychological Science Faculty Publications and Presentations

Background: The COVID-19 pandemic brought an increased incidence of disease and mortality in the world at large, making it a particularly salient and stressful life event. For those individuals residing in Latin America, the pandemic was met with fragmented healthcare systems, economic downturn, and sociopolitical crisis which puts autistic individuals at risk for more detrimental outcomes. Behavioral and emotional challenges experienced by autistic individuals at the beginning of the pandemic could later develop into more severe symptomatology as the pandemic progresses. The present study aimed to explore changes in dysregulated (overt and internalizing) behaviors and preoccupation with getting sick during …

Metagenomic Analysis Unveils The Microbial Landscape Of Pancreatic Tumors, Sheema Khan, Goutam Banerjee, Saini Setua, Daleniece Jones, Bhavin Chauhan, Anupam Dhasmana, Pratik Banerjee, Murali M. Yallapu, Stephen Behrman, Subhash C. Chuahan

School of Medicine Publications and Presentations

The composition of resident microbes in the human body is linked to various diseases and their treatment outcomes. Although studies have identified pancreatic ductal adenocarcinoma (PDAC)-associated bacterial communities in the oral and gut samples, herein, we hypothesize that the prevalence of microbiota in pancreatic tumor tissues is different as compared with their matched adjacent, histologically normal appearing tissues, and these microbial molecular signatures can be highly useful for PDAC diagnosis/prognosis. In this study, we performed comparative profiling of bacterial populations in pancreatic tumors and their respective adjacent normal tissues using 16S rRNA-based metagenomics analysis. This study revealed a higher abundance …

Limit Distributions Of Products Of Independent And Identically Distributed Random 2 × 2 Stochastic Matrices: A Treatment With The Reciprocal Of The Golden Ratio, Santanu Chakraborty

School of Mathematical and Statistical Sciences Faculty Publications and Presentations

Consider a sequence (Xn)n≥1 of i.i.d. 2×2 stochastic matrices with each Xn distributed as μ. This μ is described as follows. Let (Cn,Dn)T denote the first column of Xn and for a given real r with 012 is very challenging. Considering the extreme nontriviality of this case, we stick to a very special such r, namely, r=√5−12 (the reciprocal of the golden ratio), briefly mention the challenges in this nontrivial case, and completely identify λ for a very special situation.

Turing Patterns In A P-Adic Fitzhugh-Nagumo System On The Unit Ball, L. F. Chacón-Cortés, C. A. Garcia-Bibiano, Wilson A. Zuniga-Galindo

School of Mathematical and Statistical Sciences Faculty Publications and Presentations

We introduce discrete and p-adic continuous versions of the FitzHugh-Nagumo system on the one-dimensional p-adic unit ball. We provide criteria for the existence of Turing patterns. We present extensive simulations of some of these systems. The simulations show that the Turing patterns are traveling waves in the p-adic unit ball.

Functionalized Thermoplastic Polyurethane Nanofibers: An Innovative Triboelectric Energy Generator, Julia I. Salas, Diego De Leon, Sk Shamim Hasan Abir, Mohammed Jasim Uddin, Karen Lozano

Mechanical Engineering Faculty Publications and Presentations

A triboelectric nanogenerator (TENG) is one of the most significantly innovative microdevices for built-in energy harvesting with wearable and portable electronics. In this study, the forcespinning technology was used to synthesize a nanofiber (NF) mat-based TENG. Polyvinylidene fluoride (PVDF) membrane was used as the negative triboelectric electrode/pole, and chemically designed and functionalized thermoplastic polyurethane (TPU) was used as the positive electrode/pole for the TENG. The electronic interference, sensitivity, and gate voltage of the synthesized microdevices were investigated using chemically modified bridging of multi-walled carbon nanotubes (MWCNT) with a TPU polymer repeating unit and bare TPU-based positive electrodes. The chemical functionality …

Safety And Immunogenicity Of An In Vivo Muscle Electroporation Delivery System For Dna-Hsp65 Tuberculosis Vaccine In Cynomolgus Monkeys, Monique Ribeiro De Lima, Ana C. Leandro, Andreia Lamoglia De Souza, Marcio Mantuano Barradas, Eric Henrique Roma, Ana Teresa Gomes Fernandes, Gabrielle Galdino-Silva, Joyce Katiuccia M. Ramos Carvalho, Renato Sergio Marchevsky, John L. Vandeberg

School of Medicine Publications and Presentations

A Bacille Calmette–Guérin (BCG) is still the only licensed vaccine for the prevention of tuberculosis, providing limited protection against Mycobacterium tuberculosis infection in adulthood. New advances in the delivery of DNA vaccines by electroporation have been made in the past decade. We evaluated the safety and immunogenicity of the DNA-hsp65 vaccine administered by intramuscular electroporation (EP) in cynomolgus macaques. Animals received three doses of DNA-hsp65 at 30-day intervals. We demonstrated that intramuscular electroporated DNA-hsp65 vaccine immunization of cynomolgus macaques was safe, and there were no vaccine-related effects on hematological, renal, or hepatic profiles, compared to the pre-vaccination parameters. No tuberculin …

Rare Presentation Of Postpericardiotomy Syndrome After Left Atrial Myxoma Removal, Jessy Feng, Shyama Appareddy, Yaman Gibran, Aryana Garza, Jacqueline Luevano, Gustavo Garcia

School of Medicine Publications and Presentations

Postpericardiotomy syndrome (PPS) is a known complication of cardiac valve surgery, but it has not been commonly reported as a postoperative complication of cardiac myxoma removal. A 78-year-old female with hypertension and atrial fibrillation presenting with angina was found to have a large left atrial myxoma (7.5 cm × 4.4 cm). The myxoma was resected; however, 1-week postoperation hemoglobin and blood pressure decreased with elevated erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP). Limited transthoracic echocardiogram (TTE) showed moderate pericardial effusion, confirming the diagnosis of PPS. This case highlights the importance of monitoring patients postremoval of myxoma for symptoms of …

Metformin Alleviates Hepatic Iron Overload And Ferroptosis Through Ampk-Ferroportin Pathway In Hfd-Induced Nafld, Fangzhi Yue, Ying Shi, Shanyu Wu, Lin Xing, Dan He, Lin Wei, Anqi Qiu, Ryan D. Russell, Dongmei Zhang

Health & Human Performance Faculty Publications and Presentations

Highlights

• Metformin alleviates HIO and ferroptosis in HFD-induced NAFLD

• FPN is involved in the molecular mechanism of metformin on HIO in HFD-induced NAFLD

• Metformin upregulates FPN expression by reducing lysosomal ubiquitination degradation

Summary

Metformin prevents progression of non-alcoholic fatty liver disease (NAFLD). However, the potential mechanism is not entirely understood. Ferroptosis, a recently recognized nonapoptotic form of regulated cell death, has been reported to be involved in the pathogenesis of NAFLD. Here, we investigated the effects of metformin on ferroptosis and its potential mechanism in NAFLD. We found that metformin prevented the progression of NAFLD, and alleviated hepatic iron …

Metformin Alleviates Hepatic Iron Overload And Ferroptosis Through Ampk-Ferroportin Pathway In Hfd-Induced Nafld, Fangzhi Yue, Ying Shi, Shanyu Wu, Lin Xing, Dan He, Lin Wei, Anqi Qiu, Ryan D. Russell, Dongmei Zhang

Health & Human Performance Faculty Publications and Presentations

Highlights

• Metformin alleviates HIO and ferroptosis in HFD-induced NAFLD

• FPN is involved in the molecular mechanism of metformin on HIO in HFD-induced NAFLD

• Metformin upregulates FPN expression by reducing lysosomal ubiquitination degradation

Summary

Metformin prevents progression of non-alcoholic fatty liver disease (NAFLD). However, the potential mechanism is not entirely understood. Ferroptosis, a recently recognized nonapoptotic form of regulated cell death, has been reported to be involved in the pathogenesis of NAFLD. Here, we investigated the effects of metformin on ferroptosis and its potential mechanism in NAFLD. We found that metformin prevented the progression of NAFLD, and alleviated hepatic iron …

Exploring The Coverage Of Cyberchondria Addiction In Newspapers: A Perspective From The Usa, Rifat Afrin, Mumtahina Obaid, Gayle Prybutok, Ahasan Harun, Victor R. Prybutok

Information Systems Faculty Publications and Presentations

Objectives: The purpose of this study is to investigate how US newspapers reported cyberchondria from 2009 to 2021. Cyberchondria shares similarities with addiction, making it imperative to delve into its representation in media. Cyberchondria refers to an issue of excessive and repetitive internet searches for health information often accompanied by obsessive-compulsive behavior. The goal of this research is locate the frames that appear in cyberchondria coverage, look at how the frames have changed over the given time span, and assess the emotions that the news frames portray.

Method: After collecting the relevant news items, the study applies correspondence analysis, sentiment …

The Tor Algebra Of Trimmings Of Gorenstein Ideals, Luigi Ferraro, Alexis Hardesty

School of Mathematical and Statistical Sciences Faculty Publications and Presentations

Let (R,\mathfrak m,\Bbbk ) be a regular local ring of dimension 3. Let I be a Gorenstein ideal of R of grade 3. Buchsbaum and Eisenbud proved that there is a skew-symmetric matrix of odd size such that I is generated by the sub-maximal pfaffians of this matrix. Let J be the ideal obtained by multiplying some of the pfaffian generators of I by \mathfrak m; we say that J is a trimming of I. Building on a recent paper of Vandebogert, we construct an explicit free resolution of R/J and compute a partial DG algebra structure on this …

The Accuracy Of Automatic And Human Live Captions In English, Pablo Romero-Fresco, Nazaret Fresno

Writing and Language Studies Faculty Publications and Presentations

Closed captions play a vital role in making live broadcasts accessible to many viewers. Traditionally, stenographers and respeakers have been in charge of their production, but this scenario is changing due to the steady improvements that automatic speech recognition has undergone in recent years. This technology is being used to create intralingual live captions without human assistance and broadcasters have begun to explore its use. As a result, human and automatic captions co-exist now on television and, while some research has focused on the accuracy of human live captions, comprehensive assessments of the accuracy and quality of automatic captions are …

Aged And Induced-Premature Ovarian Failure Mouse Models Affect Diestrus Profile And Ovarian Features, Ana Carolina Zucon Bacelar, Nataira Regina Momesso, Felipe Haddad Martim Pederro, Alaíde Gonçalves, Edilson Ervolino, Antonio Hernandes Chaves-Neto, Cláudia Cristina Biguetti, Mariza Akemi Matsumoto

School of Podiatric Medicine Publications and Presentations

Sex hormones exert a wide influence on several systems of the human body, especially in women, who undergo intense changes in the trans and postmenopausal periods. Different experimental models are used to mimic these conditions; however, the impact on hormonal profile may be different. This study aimed to analyze and compare vaginal cytology of different post-estropausal mice models, along with their microscopical ovarian features. Forty-six C57BL/6J female mice with the ages of 4, 6 and 18 months at the beginning of the experiment, weighing about 25–28 grams, constituted five groups: NC–(negative control) animals with no treatment, OVX-SHAM—sham ovariectomized, OVX–ovariectomized, VCD–medicated …

Chronic Jet Lag Alters Gut Microbiome And Mycobiome And Promotes The Progression Of Mafld In Hfhfd-Fed Mice, Ruoyi Zheng, Xingwei Xiang, Ying Shi, Anqi Qiu, Xin Luo, Junyan Xie, Ryan D. Russell, Dongmei Zhang

Health & Human Performance Faculty Publications and Presentations

Metabolic dysfunction-associated fatty liver disease (MAFLD) is the most common chronic liver disease worldwide. Circadian disruptors, such as chronic jet lag (CJ), may be new risk factors for MAFLD development. However, the roles of CJ on MAFLD are insufficiently understood, with mechanisms remaining elusive. Studies suggest a link between gut microbiome dysbiosis and MAFLD, but most of the studies are mainly focused on gut bacteria, ignoring other components of gut microbes, such as gut fungi (mycobiome), and few studies have addressed the rhythm of the gut fungi. This study explored the effects of CJ on MAFLD and its related microbiotic …