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University of South Florida

Internal Medicine Faculty Publications

2019

Aging

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Bone Benefits Of Fish Oil Supplementation Depend On Its Epa And Dha Content, Haissam Abou-Saleh, Allal Ouhtit, Ganesh V. Halade, Md Mizanur Rahman Nov 2019

Bone Benefits Of Fish Oil Supplementation Depend On Its Epa And Dha Content, Haissam Abou-Saleh, Allal Ouhtit, Ganesh V. Halade, Md Mizanur Rahman

Internal Medicine Faculty Publications

Licensee MDPI, Basel, Switzerland. The preventive effect of high-dose (9%) regular-fish oil (FO) against bone loss during aging has been demonstrated, but the effects of a low-dose (1%–4%) of a highly purified concentrated FO (CFO) has not been elucidated. The aim of this study was to determine the dose-dependent effect of a CFO against bone loss in C57BL/6 female mice during aging. Twelve-month old mice were fed with 1% and 4% CFO and 4% safflower oil (SFO) diets, including a group with a 4% regular-FO diet and a group with a lab chow diet for 12 months. Bone mineral density …