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Cognitive Remediation Of Working Memory Deficits In Children With Chronic Health Conditions: Tailoring Cogmed Training To Address Barriers To Adherence, Kelsey Smith
Theses and Dissertations
Objective: Children with sickle cell disease (SCD) and cancer are at risk for working memory impairment due to the disease and treatment. However, inconsistency in adherence to cognitive training programs conducted with this population suggests that adaptations are necessary in order to improve the effectiveness of this intervention. In addition, it is unclear whether gains in working memory translate to improvement in classroom functioning.
Methods: Children engaged in cognitive training exclusively over the summer in order to improve adherence to Cogmed Working Memory Training. A total of 17 children ages 7- 17 with a diagnosis of SCD (n = 14) …
The Effects Of Exercise Training On Cardiovascular-Related Circulating Micrornas, Jacob Luther Barber
The Effects Of Exercise Training On Cardiovascular-Related Circulating Micrornas, Jacob Luther Barber
Theses and Dissertations
PURPOSE: MicroRNAs (miRNAs) are small regulatory RNAs that post transcriptionally modify mRNAs and control gene expression. Circulating miRNAs are significantly altered following a single session of exercise, however the effects of exercise training on the circulating miRNA profile is unclear. Therefore, the purpose of the present study was to determine the effects of endurance exercise training on the abundance of targeted circulating miRNAs and the association of changes in miRNA levels with concomitant changes in cardiometabolic traits, in a subsample of adults from the HERITAGE Family Study.
METHODS: This exploratory analysis examined 20 previously sedentary adults from the HERITAGE Family …