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Intricacies Of Development : The Impact Of Maternal Experience And Isolation On The Social Development Of Juvenile Male Rats, Lillian Maria Christon

Master's Theses

Reproductive experience induces changes in females. Parity-related differences in maternal treatment of offspring can induce enduring changes in offspring. The relationships between maternal experience, early social isolation, and development were explored in rodents in this experiment. Male rats were weaned from multiparous (MP) and primiparous (PP) mothers and placed into isolation or social housing for four weeks. They were then observed in a social-interaction test. Social behavior and neural oxytocin and vasopressin were assessed post-testing, while corticosterone levels were measured across the four weeks. Weaning was extremely stressful for all offspring. PP- and MP-raised pups exhibited differences in social behavior, …