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University of Richmond

Theses/Dissertations

1980

Biology

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Reproductive And Mutagenic Effects Of 5-Thio-D-Glucose Injections In Male Mice, Mus Musculus, Icr Strain, Mary E. Mcmanaway Aug 1980

Reproductive And Mutagenic Effects Of 5-Thio-D-Glucose Injections In Male Mice, Mus Musculus, Icr Strain, Mary E. Mcmanaway

Master's Theses

Adult male ICR mice of proven fertility were intraperitoneally injected daily with 60 mg/kg of 5-thio-D-glucose for 28 days. Body weights of treated male mice were unaffected during the experimental period. Relative testicular weights were significantly reduced at 121 days after initial injections in 5-thio treated males, but no significant decrease was observed at 28 days.

Onset of sterility was estimated to occur at approximately 4 weeks and persisted for 5 to 6 weeks after cessation of treatment at which time fertility was restored.

Beginning with the first injections and continuing for 121 days, the males were mated with untreated …


The Effects Of Photoperiod And Melatonin Injections On The Reproductive System Of Male Mice, Mus Musculus, Icr Strain, Margaret Ann Shugart Aug 1980

The Effects Of Photoperiod And Melatonin Injections On The Reproductive System Of Male Mice, Mus Musculus, Icr Strain, Margaret Ann Shugart

Master's Theses

The reproductive effects of long (24L:OD), natural (14L:lOD), and short (1L:23D) photoperiods were studied in the male mouse, Mus musculus, ICR strain. One third of the mice in each photoperiodic regimen were sacrificed after 45 days. Half of the remaining mice in each regimen received daily melatonin (5-methoxy-N-acetyl tryptamine) injections for 45 additional days. Body weights, testicular and accessory sex organ weights were measured and microscopic examinations of the testes were made. Plasma testosterone levels were determined using radioimmunoassay. Other organ (pituitary, kidney, adrenal, thymus, thyroid) weights were also obtained.


Seasonal Sexual Cycle Of Nerodia Taxispilota (Serpentes: Colubridae) At The Northeastern Edge Of Its Range, David Roland White Jan 1980

Seasonal Sexual Cycle Of Nerodia Taxispilota (Serpentes: Colubridae) At The Northeastern Edge Of Its Range, David Roland White

Master's Theses

The seasonality of the sexual cycle of Nerodia taxispilota at the northeastern edge of its range was elucidated from specimens collected over a two-year period (1978-1979) from the Appomattox River near Hopewell, Virginia. The investigation centered on morphological changes in the testis of males and vitellogenesis and embryo development in females. Related reproductive parameters also studied were body size differences, seasonal sex ratios, comparative tail lengths, and tail mutilation.

Male and female cycles closely resembled those of other temperate zone colubrids. Spermatogenesis began in May and testis size peaked in late August. Testis length showed a time lag when compared …