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Effects Of Omega-3 Fatty Acids And Hypoxia On Progesterone Biosynthesis And Mitochondrial Morphology In The Corpus Luteum, Brian Krum
Master's Theses
The corpus luteum is a transient steroidogenic endocrine gland that forms from the remnants of the ovulatory follicle. This gland is responsible for the synthesis and secretion of the hormone progesterone, which is critical for the establishment and maintenance of pregnancy. In a non-pregnant cow, PGF2a is released from the uterus to regress the corpus luteum. However, in the case of pregnancy, the embryo must mitigate PGF2a synthesis to prevent corpus luteum regression. If the embryonic signal is either too late or too weak, uterine PGF2a secretion may result in corpus luteum regression and termination of pregnancy. Omega-3 fatty acids …