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A Bridge Too Far? Risks And Benefits Of Perioperative Bridging Therapy, Jordan Buchholz Jan 2018

A Bridge Too Far? Risks And Benefits Of Perioperative Bridging Therapy, Jordan Buchholz

Physician Assistant Scholarly Project Papers

The long-term use of oral anticoagulants is common among certain high-risk patient populations for the prevention of thromboembolic events such as stroke, pulmonary embolism (PE), and other systemic events. According to Garwood et al. (2017) it is estimated that 15-20% of chronically anticoagulated patients will undergo a surgery or procedure that will require anticoagulation interruption annually. During this interruption period, “bridging” anticoagulant therapy is often utilized with unfractionated heparin or low-molecular weight heparin to ensure adequate anticoagulation is achieved (Ayoub et al., 2016). However, there has been an ongoing debate whether or not the benefits of perioperative anticoagulant bridging therapy …


Verbal Learning And Memory In Adults With Mild, Moderate And Severe Closed Head Injury, Paula J. Bergloff Aug 1995

Verbal Learning And Memory In Adults With Mild, Moderate And Severe Closed Head Injury, Paula J. Bergloff

Theses and Dissertations

One of the most prevalent of cognitive dysfunctions associated with closed head injury is impaired_memory function. The current study examined qualitative and quantitative aspects of learning and memory to define the effects of mild head injury in comparison to moderate and severe head injury and a sample of normal controls.

Forty five survivors of severe (n=15), moderate (n=15) and mild (n=15) closed head injury were compared with age and education matched controls (n=15) on the California Verbal Learning Test (CVLT) and the Wechsler Memory Scale (WMS). On CVLT learning trials, head injured groups recalled less than controls, with the severely …