Digital Commons Network^™

Genome-Wide Analysis Of Methylome In The Mouse Brain Using Long-Read Sequencing Technology, Zachary Even, He Huang, Ramkumar Mathur, Xusheng Wang

Arts & Sciences Undergraduate Showcase

DNA methylation is an epigenetic modification that transfers a methyl group onto the C-5 position of the cytosine to form 5-methylcytosine. DNA methylation regulates gene expression by recruiting proteins involved in gene repression or by inhibiting the binding of transcription factor(s) to DNA, especially in regulation of Allele Specific Expression (ASE). In this study, we used Oxford Nanopore long-read sequencing technology to profile methylome in the two inbred mouse strains, C57BL/6J (B6) and DBA/2J (D2). Compared with bisulfite conversion followed by Illumina Sequencing, long-read sequencing technology allows us to achieve much longer read length of 4,653.675 base pairs on average …

The North Dakota Dual Aurora Camera (Noddac), A Student-Led Citizen Science Project: One-Year Retrospective, Future Developments, And Scientific Potential, Vincent Ledvina, Elizabeth Macdonald, Steven Collins, Michael Mccormack, Timothy Young, Wayne Barkhouse

Arts & Sciences Undergraduate Showcase

The North Dakota Dual Aurora Camera (NoDDAC) is a student-led project operated in conjunction with the University of North Dakota (UND), the LiveAuroraNetwork, and Aurorasaurus citizen science. Aurora cameras are valuable tools for aurora chasers, and scientists, providing ground-truth visual data to gauge auroral activity, yet at midlatitudes, these facilities are few in number. Deploying aurora cameras in these areas provides a valuable resource for aurora-chasing communities, but also demonstrates scientific merit as the analysis of rare phenomena, such as STEVEs, benefit from multiple geographic observations. What makes this project unique is the student initiative being based at a university …

Environmental Impacts Of Contact Lens Waste, Abigail Wilhelmi

Arts & Sciences Undergraduate Showcase

Contact lenses have been used for decades to correct vision, and over 150 million people use contact lenses today. The materials used to make contact lenses have evolved drastically, but ultimately resulted in a specific plastic, silicone-derived hydrogel, which provides maximal comfort and clear vision, while also maintaining the eye health of the user. Contact lenses have enhanced the lives of many people, but a topic that is often left out of contact lens discussions is that of plastic waste. Single-use plastic and increased plastic pollution have recently been areas of concern and expanded research. Contact lenses are often forgotten …

Sexual Violence In Prisons: Inmate Subculture And Demographics Of Fear, Mackenzie Leroux

Arts & Sciences Undergraduate Showcase

Prison sexual violence has been a prominent issue since the establishment of correctional facilities. However, the issue was dismissed due to the stigmatization of the inmate population. As a result, there were no documented policies, statutes, or laws that prohibited prison rape or imposed sanctions upon offenders. The attention towards inmates rights, specifically regarding sexual assault, began to be addressed in the media in the 1990s. Through past offender stories, legal cases, and an overall sense of awareness, the Prison Rape Elimination Act was established in 2003. This act outlawed any sexual relationships between either inmates, or inmates and correctional …

Building The Path To Early Alzheimer's Prediction Using Machine Learning, Kincaid Rowbotham, Ling Li, Xusheng Wang

Arts & Sciences Undergraduate Showcase

Alzheimer’s disease (AD) is the most common form of dementia and one of the most prominent challenges of precision healthcare is early identification of AD. To combat this latency in diagnosis, integration of machine learning has been exercised for more cost efficient and powerful diagnostic tools. Specifically, we have developed a workflow for identifying AD within a given sample. Utilizing cerebral cortex proteomic data as a baseline, we were able to test two different forms of feature selection and 6 different machine learning methods. The best performing of these combinations was using a Support Vector Machine (SVM) method with features …

The Wrong Side Of The Wall, Grant Mcmillan

Greenway Press Chapbooks

No abstract provided.

Swallow's Nest: Birdwatching Poems, Karissa Wehri

Greenway Press Chapbooks

No abstract provided.

The Year Of Brood Viii, Jona L. Pederson

Greenway Press Chapbooks

No abstract provided.

Mindful Wandering: Nature And Global Travel Through The Eyes Of A Farmgirl Scientist, Rebecca J. Romsdahl

Digital Press Books

Mindful Wandering is an inspiring blend of memoir, travelogue, and environmental manifesto. As a translational ecologist, Rebecca Romsdahl is trained to ask critical questions about how we can improve our human relationships with the natural world for a sustainable, resilient future. As a farmgirl, she learned how to observe nature and life through the changing seasons. In this collection of essays spanning two decades, Romsdahl weaves these ideas together as she travels our changing world. From a Minnesota farm to the mountains of Peru and the edge of the Sahara Desert, she explores strategies for sustainability and resilience, and advocates …

Open Access Explained, Zeineb Yousif, Brittany Fischer

Librarian Posters and Presentations

This workshop gives a basic overview of the open access movement. By the end of this workshop you should be able to:

• Identify what open access is
• Understand why Open Access is important
• Learn how it can benefit you as a researcher, student, or professional
• Know where to find additional resources for help

This workshop can be modified to match the particulars of the campus where it is being presented.

A Framework For Anti-Racist Information Literacy Instruction: Exemplar, Process, And Structure, Kristen Borysewicz, Devon Olson

Librarian Posters and Presentations

Are instructional librarians having needed conversations with patrons about how research can perpetuate systemic discrimination and racism? A framework developed collaboratively between UND librarians and focused on exemplar, process, and structure provides a starting point. Learn how you can interrogate the conceptual processes and information architecture behind academic knowledge dissemination systems in order to foster a more anti-racist, equitable, and critical form of information literacy.

What Is Edi Anyway?, Mary Soucie, Jackie Frederick, Karlene T. Clark

Librarian Posters and Presentations

EDI? BIPOC? He/His vs They/Them? Want to build an inclusive community for all patrons but not sure where to start? The NDLA Equity, Diversity, and Inclusion Committee will share the purpose of the committee and how the work can positively impact patrons at your institutions. Presenters will answer common questions from those seeking to expand their knowledge of EDI issues and offer concrete examples from North Dakota libraries.

Renovations And How Ada Updates Were Addressed At An Academic Institution, Karlene T. Clark, Brittany Fischer, Rebecca Brown

Librarian Posters and Presentations

After a three-year renovation of the Chester Fritz Library, the presenters were tasked with reviewing the building for updates done and how they addressed needs within the Americans with Disabilities Act (ADA). This presentation covers pre-renovation concerns, what changes were made, the process used to determine the criteria if an issue had been resolved, and what their next steps are going forward.

Receiver Apprehension & Listener Style Retention, Karlene T. Clark

Librarian Posters and Presentations

Receiver apprehension is the anxiety patrons feel when approaching someone for help. There are different types of ways in which people process information, some of which can be a detriment to the person hoping to learn something or just have a question answered. This presentation looks at the different styles of listeners and how librarians can utilize this knowledge to better meet the needs of patrons coming to the reference desk for assistance.

Laboratory Capabilities, University Of North Dakota. Energy And Environmental Research Center

EERC Brochures and Fact Sheets

Fact sheet about the Energy & Environmental Research Center’s (EERC’s) laboratory capabilities including reservoir characterization, organic geochemistry, fluid sampling, and material analysis. A list of publications and laboratory information is also included.

Completion Design Evolution For Saltwater Disposal Injection Wells In The Bakken Play, Darren D. Schmidt, Jeffrey W. Bader, Ashleigh Day, Mark Bohrer

EERC Publications

Disposal of produced water is a critical component of unconventional oil development. The significant increase in Bakken production over the past decade in concert with the expansion of saltwater disposal wells geographically, places new demands on the storage reservoir. Development has spurred investigations of the reservoir and well performance.

The Use Of 19th Century Hairstyling, Techniques, And Products For Theatrical Production, Shelby Hazel

Theatre Arts Posters and Presentations

Trendy hairstyles and hairstyling techniques have been around for centuries, but have you ever wondered what getting ready in the morning was like for an upper-class woman in the 19^th century? These women would spend time getting ready for the day in their dressing room or toilette, where they would pomade, powder, and decorate their hair with elaborate curls and ornaments. A popular style of the 1830s was the a la Chinoise (ah la shen-wahs’). This hairstyle included parting the hair in the middle and pulling it smoothly to the temples where it was arranged in hanging sausage-shaped curls, …

Overland Trail Game: A Lesson Plan, Alexandria Weber

Arts & Sciences Undergraduate Showcase

Educators of all levels are continuously looking for new ways to engage students with the content. Some post-secondary level instructors have embraced a unique method of role-playing games in their classrooms. Specially, many of these teachers have begun using Mark Carnes's pedagogy of Reacting to the Past. This method gamifies historical content to make it easier for students to relate to a diverse array of historical actors. To play these games, students must achieve a specific goal while pretending to be an assigned historical figure. Reacting to the Past lesson plans are one of a kind, high quality, peer-reviewed teaching …

Traditional Korean Wig: Ga-Chae(가체) - The Queen Style: Eoyeo Hair(어여머리), Daniel Jung

Theatre Arts Posters and Presentations

Whether it was thousands of years ago or now, despite the gender, people's obsession and interest in beauty and wealth were the same, and beauty was a symbol of wealth and family power during the Joseon Dynasty (1392 – 1897) as well. Influenced by the Ming Dynasty from China, women in Joseon started to wear wigs called Ga-Chae, which were loops of thick and rich black hair braided together. Among all the different kinds of Ga-Chae, I chose to do a deeper research in the Queen style of Ga-Chae, called the Eoyeo Hair. This wig style was only allowed for …

State Energy Research Center, University Of North Dakota. Energy And Environmental Research Center

EERC Brochures and Fact Sheets

Fact sheet about the State Energy Research Center (SERC). Highlights the Energy & Environmental Research Center’s (EERC’s) technology development, skilled workforce, and funding sources.

Geology Study – Drilling Down At Red Trail Energy, University Of North Dakota. Energy And Environmental Research Center

EERC Brochures and Fact Sheets

Fact sheet about a 2019–2020 geophysical survey near Richardton, North Dakota. The survey investigated the area’s feasibility as a CO₂ storage site, as part of the Red Trail Energy carbon capture and storage (CCS) research effort. Summarizes survey process and results.

Stump Speech Regarding The Accomplishments Of Attorney General Langer, Unknown

William Langer Papers

This three page, undated and untitled speech regards the accomplishments of William Langer, who served as North Dakota Attorney General from 1916 until 1920. Langer is praised as relentless opponent of graft and corruption, a true American patriot, and a moral crusader in support of prohibition and temperance.

Effect Of Cftr Modulators On Respiratory Function In Adults With Cystic Fibrosis, Melissa Severson

Physician Assistant Scholarly Project Posters

CysticFibrosis(CF)isanautosomalrecessivedisorderthatshortensone’slifeduetoitseffectonthecysticfibrosistransmembraneregulator(CFTR)gene.CFTRmodulatormedicationscancorrecttheCFTRgeneandconsistofapotentiator(ivacaftor),andcorrector(lumacaftor,tezacaftorandelexacaftor).ThisresearchandliteraturereviewsoughttoevaluateiflungfunctionimprovedinanindividualwithgeneticallyconfirmedCFafterbeingstartedonCFTRmodulatormedications.Tocompletethereview,sixdatabasesweresearched:CINAHL,PubMed,ClinicalKey,CochraneLibrary,EmbaseandDynamedPlus.BothkeywordandmeshtermswereusedtodefineasetoftheliteraturediscussingCFandCFTRmodulatoruse.Atotalof24studieswereincludedandmettheinclusioncriteriaof:peerreviewed,publishedwithinthepastsixyears,greaterthan20studyparticipants,andwerenotlimitedcasereports.Phase2studieswereincludedforelexacaftor-tezacaftor-ivacaftorandtezacaftor-ivacaftor,duetolimitedresearchinthisarea.Researchindicatedthativacaftorimprovedpercentpredictedforcedexpiratoryvolumeinonesecond(ppFEV1)inindividualswithG551D,non-G551Dgatingmutations,Gly-Asp-CFTRandARG117HISmutations.Elexacaftor-tezacaftor-ivacaftorimprovedppFEV1inheterozygousandhomozygousPhe508delgreaterthanivacaftororlumacaftor-ivacaftor.Ivacaftorandlumacaftor-ivacaftormayhaveagedependentchangesonppFEV1.IndividualswithppFEV1<40%appeartohaveapositiveresponsetotreatment,howevertheymayhaveincreasedsideeffectsandresponsemaybedelayed.Additionalresearchisneededonagedependent,longitudinalresponse,andefficacyoftreatment.

Cholinergic Antagonist Use And The Risk Of Developing Dementia In Persons Aged 65 Years And Olders, Heidi N. Artz Schmaltz

Physician Assistant Scholarly Project Posters

Anticholinergic medications cause a therapeutic or negative effect in the human body by blocking neuronal cholinergic receptors, thereby inhibiting the binding of acetylcholine in the central nervous system and the peripheral nervous system. These medications have short-term side effects including dry mouth, constipation, visual impairments, or delirium; however, research regarding the long-term side effects is limited. The purpose of this systemic literature review is to determine the correlation between prolonged exposure to anticholinergic medications and the development of dementia. The literature databases PubMed, Cochrane Review, Science Direct (Elsevier), and DynaMed were utilized in this review. Journal articles published within the …

Comparative Research Of Effective Treatment Measures For Postpartum Depression, Aunica Novacek

Physician Assistant Scholarly Project Posters

Postpartum depression is a mood disorder that includes depressive symptoms during the time period following childbirth. There are various possibilities for what may cause this disorder, but the drastic change in hormones after delivery can play a role. With the chance this disorder may be fatal to both the mother and child, an appropriate, effective, and safe treatment is necessary to control depressive symptoms. The standard, first line pharmacotherapeutic option is a selective serotonin reuptake inhibitor (SSRI) antidepressant. SSRI antidepressants are well understood, but these medications may take time to become effective. Knowing this, medical professionals can find a more …

P.M. Dosing Outcomes Of Ace Inhibitors Or Angiotensin Ii Receptor Blockers In Hypertension Versus P.M. Dosing In Hypertension With Comorbidities, Savana Kramer

Physician Assistant Scholarly Project Posters

• Introduction: The purpose of this research is to compare P.M. dosing outcomes of angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs) in those with hypertension and hypertension plus chronic kidney disease or diabetes.

• Research Methods: Three databases were searched including PubMed, ClinicalKey, and DynaMed with a time frame of 15 years. Studies chosen for review were peer reviewed, and included randomized control trials, systematic reviews, meta-analyses, and a preclinical animal trial.

• Discussion: The research shows evidence of reduced blood pressures throughout the night and into the next day, decreased proteinuria, and decreased cardiovascular events when …

Comparison Of Conjunctive Probiotic Use Versus No Probiotic Use In Outcomes Of Antibiotic-Associated Diarrhea, Samantha Simley

Physician Assistant Scholarly Project Posters

Antibiotics are utilized in the medical community for the treatment of bacterial infections. Consequently, the use of antibiotics may result in certain gastrointestinal side effects. Antibiotic-associated diarrhea is one side effect that can be seen in patient populations that are on an antibiotic regimen. Due to this side effect profile, patient compliance on an antibiotic regimen may be compromised. This lack in patient compliance led to increased interest to determine if there are treatment options available to prevent or reduce instances of antibiotic-associated diarrhea. One treatment option of interest includes the use of probiotics. The purpose of this literature review …

Ketamine In Refractory Asthma Exacerbations, Stephanie Frentzel

Physician Assistant Scholarly Project Posters

Asthma is a chronic, non-curable respiratory disease that has multi-factorial effects on the bronchial mucosa. Despite optimal prevention and standardized first line asthma care the symptoms can deteriorate leading into an asthma exacerbation which is a medical emergency. Purpose:

• To determine the efficacy of ketamine use as an adjunctive medication for acutes severe asthma exacerbations that had failed standard guideline directed treatments. Methods: • Relevant databases were searched looking for ketamine use in asthma exacerbations.

• The inclusion material consists of pediatric and adult populations in available systematic reviews, randomized control trials, meta-analysis, pilot studies, case reports, and peer-reviewed …

The Impact Of Hormone Therapy On Cardiovascular And Bone Health In Women With Premature Or Early Menopause, Traci L. Leitheiser

Physician Assistant Scholarly Project Posters

Objective: • The Women's Health Initiative (WHI) studies were a catalyst for the dramatic decline in the number of postmenopausal women being prescribed hormone therapy (HT). • The WHI published the largest randomized, double-blind, placebocontrolled trial regarding the use of HT in postmenopausal women with a mean age of 63 years. • One group of women thought to benefit from HT but have often been denied HT based on the WHI studies’ results is premature and early menopausal women. • The purpose of this literature review was to compare the WHI studies’ results to studies that reviewed coronary heart disease …

Efficacy Of Pharmacologic Treatment For Orthostatic Hypotension In The Elderly Population, Abigail Moeller

Physician Assistant Scholarly Project Posters

The purpose of this literature review is to determine the efficacy and safety of pharmacologic treatments for orthostatic hypotension (OH), with an emphasis on researching the elderly population. In this review, three electronic search databases were utilized including PubMed, Google Scholar, and Dynamed from the years 1997 to 2019. Several keywords were used during the search. The specific pharmacologic agents researched for the treatment of OH included midodrine, droxidopa, pyridostigmine, and fludrocortisone. Although midodrine is the most researched and utilized pharmacologic treatment of OH, this drug may not be the best option when it comes to treatment in the elderly …