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Angioplasty Vs. Cryoplasty For The Treatment Of Symptomatic Peripheral Vascular Disease: A Retrospective Review Looking At Comparative Outcomes, Jordan Knepper, John Welker Sep 2009

Angioplasty Vs. Cryoplasty For The Treatment Of Symptomatic Peripheral Vascular Disease: A Retrospective Review Looking At Comparative Outcomes, Jordan Knepper, John Welker

Undergraduate Medical Student Research

In 2007 it was reported that eight million Americans are affected by Peripheral Vascular Disease (PVD) and of these affected, around ten percent report being symptomatic (Mayo Clinic). With such a large percentage of Americans affected by this problem, many providers who care for these patients opt to treat with the least invasive option and then progress to more invasive means if necessary. To date, Percutaneous Transluminal Angioplasty (PTA) has been the preferred minimally invasive endovascular treatment option for symptomatic PVD. Though this option is preferred and used extensively, there are concerning short and long term potential consequence such as …


The Effect Of Experiential Education On Students' Attitudes About Complementary & Alternative Medicine Practices, Eva Kaul, Mariebeth Velasquez Sep 2009

The Effect Of Experiential Education On Students' Attitudes About Complementary & Alternative Medicine Practices, Eva Kaul, Mariebeth Velasquez

Undergraduate Medical Student Research

OBJECTIVES: To evaluate the effectiveness of an experiential Complementary and Alternative Medicine (CAM) education session in changing medical students beliefs, attitudes, and comfort level with CAM. DESIGN: Students attended a 3 hour class on Mindfulness Based Stress Reduction with a trained provider, and completed a Likert scale survey of their agreement with various statements about CAM both pre and post-session. ASSESSMENT: Changes in agreement with 7 of the 10 items reached statistical significance, including increase in students' subjective level of knowledge about CAM, decrease in the belief that CAM is too controversial to discuss with patients, increase in perceived ability …


An Interactive Telehealth Program To Improve Attitudes Toward Treating Diabetes, Richard Wintermute, Kathleen Colleran Sep 2009

An Interactive Telehealth Program To Improve Attitudes Toward Treating Diabetes, Richard Wintermute, Kathleen Colleran

Undergraduate Medical Student Research

Background Currently 60% of the United States population is overweight or obese. Recent data has shown that 7% of the US population has Diabetes Mellitus Type 2 and New Mexico is above the average at 9%. Many studies have shown that good glycemic control with lifestyle changes or Metformin therapy can prevent or delay microvascular and some macrovascular complications of Diabetes. These findings have not been translated into routine care especially in New Mexico in large part due to NMs largely, rural, poor and medically underserved population. The Extension for Community Healthcare Outcomes (ECHO) is a project developed at the …


Stability Of Talar Neck Fracture Fixation: A Biomechanical Comparison Of 4.0 Cannulated Headed Screws And Conical Headless Screws, Thomas Decoster, Keikhosrow Firoozbaksh, Deana Mercer, Selina Silva, Jennifer Fitzpatrick, Dylan Watson Sep 2009

Stability Of Talar Neck Fracture Fixation: A Biomechanical Comparison Of 4.0 Cannulated Headed Screws And Conical Headless Screws, Thomas Decoster, Keikhosrow Firoozbaksh, Deana Mercer, Selina Silva, Jennifer Fitzpatrick, Dylan Watson

Undergraduate Medical Student Research

Objective: The purpose of this study was to compare the mechanical stability of cannulated conical variable pitch headless (CH) screws to partially threaded 4.0 cannulated (4.0 C) screws for fixation of talar neck fractures. Methods: A controlled talar neck fracture was produced in 24 sawbone tali. The fractures were stabilized with CH screws in 12 tali and with 4.0 C screws in 12 tali. A Mechanical Testing System machine was used to apply a dorsally-directed shear force to the talar head with the talus body fixed to simulate walking and the clinical mode of failure of talar neck fracture fixation. …


The Effects Of Glucose On Proteasome Activities In Neuronal Cells Under In Vitro Ischemia Conditions, Grace Xu Sep 2009

The Effects Of Glucose On Proteasome Activities In Neuronal Cells Under In Vitro Ischemia Conditions, Grace Xu

Undergraduate Medical Student Research

Reducing the volume of brain damage after stroke has been a focus of recent research due to its effect on recovery time and quality of life. Changes in proteasomal activities are related to ischemic damage of brain. Proteasome inhibition has been suggested as a potential treatment option for stroke. However, the mechanism of alteration of proteasomal activities in neurons under ischemic conditions is not known. In study, we investigated the role of glucose in regulating proteasomal activities in neuronal cells under ischemic condition. We found that glucose concentration had remarkable differential effect on both 20S and 26S proteasomal activities in …


The Modified Mcgoon Index Does Not Predict Mortality In Infants With Congenital Diaphragmatic Hernia, Brett Weitzel, Gerald Holmes, Rebecca Moran Sep 2009

The Modified Mcgoon Index Does Not Predict Mortality In Infants With Congenital Diaphragmatic Hernia, Brett Weitzel, Gerald Holmes, Rebecca Moran

Undergraduate Medical Student Research

Background: Infants diagnosed with congenital diaphragmatic hernia (CDH) continue to have a high mortality despite medical advances such as inhaled nitric oxide (iNO), high frequency ventilation (HFV) and/or extracorporeal membrane oxygenation (ECMO). The mortality in some studies exceeds 80%. The modified McGoon index (MMI), a ratio of pulmonary artery size to aortic size has been reported to predict survivability in these infants: infants with a MMI ≤ 1.3 have an 85% mortality: (Pediatr 2000;105:1106). Objective: To evaluate the utility of MMI in predicting mortality in our population. Design/Methods: We performed a retrospective review of all infants with CDH admitted to …


Relationship Between Mineral Content Of Breast Milk And Maternal Diet, Zachary Wilson Sep 2009

Relationship Between Mineral Content Of Breast Milk And Maternal Diet, Zachary Wilson

Undergraduate Medical Student Research

Exclusively breastfed infants require that adequate amounts of carbohydrates, fatty acids, proteins, and mineral nutrients are available to foster normal skeletal and neuromuscular growth and development. Minerals such as calcium, sodium, and potassium, which are crucial for normal physiological function, are found in variable concentrations in human milk. As well, antibodies and other rarefied minerals - selenium, zinc, manganese, and copper - are critical for protection against infection and proper function of the immune system and are supplied to the neonate by the mother's milk. Although many studies have investigated the trace mineral concentrations in breast milk (1,2) few have …


Brain Derived Neurotrophic Factor (Bdnf) Mrna Expression Levels In Mice Exposed To Learned Helplessness, Patrick Rendon Sep 2009

Brain Derived Neurotrophic Factor (Bdnf) Mrna Expression Levels In Mice Exposed To Learned Helplessness, Patrick Rendon

Undergraduate Medical Student Research

Brain Derived Neurotrophic Factor (BDNF) is associated with changes in cellular structure that occur during the development of the nervous system, and in the adult brain contributes to neural plasticity. BDNF is found in high concentrations in both the frontal cortex and hippocampus where it has been proposed to play a role in cognition and learning respectively. Low serum BDNF levels can be measured in patients with major depressive disorder, and there is a correlation between decreased BDNF levels and the severity of depression. At this time, research is attempting to solve the question of whether depression results secondary to …


Fetal Alcohol Spectrum Disorder-Associated Depression: Evidence For Reductions In The Levels Of Brain-Derived Neurotrophic Factor In A Mouse Model, Kevin Caldwell, S. Sheema, Rodrigo D. Paz, Sabrina Samudio-Ruiz, Mary Laughlin, Nathan Spence, Michael Roehlk, Sara Alcon, Andrea Allan Sep 2009

Fetal Alcohol Spectrum Disorder-Associated Depression: Evidence For Reductions In The Levels Of Brain-Derived Neurotrophic Factor In A Mouse Model, Kevin Caldwell, S. Sheema, Rodrigo D. Paz, Sabrina Samudio-Ruiz, Mary Laughlin, Nathan Spence, Michael Roehlk, Sara Alcon, Andrea Allan

Undergraduate Medical Student Research

Prenatal ethanol exposure is associated with an increased incidence of depressive disorders in patient populations. However, the mechanisms that link prenatal ethanol exposure and depression are unknown. Several recent studies have implicated reduced brain-derived neurotrophic factor (BDNF) levels in the hippocampal formation and frontal cortex as important contributors to the etiology of depression. In the present studies, we sought to determine whether prenatal ethanol exposure is associated with behaviors modeling depression, as well as with reduced BDNF levels in the hippocampal formation and/or medial frontal cortex, in a mouse model of fetal alcohol spectrum disorder (FASD). Compared to control adult …


Complementary And Alternative Medicine (Cam) Use In Pediatric Oncology: A New Horizon Or Costly Myth?, Justin Roesch, Mark Holdsworth, Stuart Winter, Dennis Raisch Sep 2009

Complementary And Alternative Medicine (Cam) Use In Pediatric Oncology: A New Horizon Or Costly Myth?, Justin Roesch, Mark Holdsworth, Stuart Winter, Dennis Raisch

Undergraduate Medical Student Research

Complementary and alternative medicines (CAMs) are increasingly being utilized in the pediatric cancer population, despite unproven risks and benefits, and significant additional cost of treatment. Objective: To identify the prevalence of CAM use and the most frequently utilized CAMs, and to examine the physiologic impact of CAM in pediatric cancer patients undergoing chemotherapy. Additional objectives included identifying the cost associated with CAM, and the rationale for CAM usage.


Ethnic Differences In Dysmorphic Features Among Children With Fetal Alcohol Spectrum Disorders, Philip May, Phillip Gossage, Matthew Smith, Barbara Tabachnick, Luther Robinson, Melanie Manning, Mauro Cecanti, Jones Lyons, Denis Viljoen, Nathaniel Khaole, David Buckley, Wendy Kalberg, Eugene Hoyme Sep 2009

Ethnic Differences In Dysmorphic Features Among Children With Fetal Alcohol Spectrum Disorders, Philip May, Phillip Gossage, Matthew Smith, Barbara Tabachnick, Luther Robinson, Melanie Manning, Mauro Cecanti, Jones Lyons, Denis Viljoen, Nathaniel Khaole, David Buckley, Wendy Kalberg, Eugene Hoyme

Undergraduate Medical Student Research

Children adversely affected by prenatal exposure to alcohol display a continuum of dysmorphic features, behavioral and neuropsychological deficits best termed fetal alcohol spectrum disorders (FASD). Alcohol exposure during critical stages of central nervous system and midfacial development leads to the observed pattern. Recent research on FASD focuses increasingly on quantifying physical traits (including head circumference, palpebral fissure length, philtrum length, morphology of the philtrum and vermilion border of the upper lip) and comparing them to specific neurocognitive findings. Various standards and cut-off points have been used by dysmorphologists to determine which of the structural features of children prenatally exposed to …


Increased Expression Of Mad2 Occurs In Association With Dnmt1 Protein Stabilization And Aberrant Cpg Island Promoter Hypermethylation During Carcinogenesis In Immortalized Bronchial Epithelial Cells, Paul Romo Sep 2009

Increased Expression Of Mad2 Occurs In Association With Dnmt1 Protein Stabilization And Aberrant Cpg Island Promoter Hypermethylation During Carcinogenesis In Immortalized Bronchial Epithelial Cells, Paul Romo

Undergraduate Medical Student Research

Physicians and scientists must join together and research the specific effects of environmental carcinogens in relation to cancer. A great model to study environmental carcinogenesis is carcinogen-induced lung cancer. We know that 30% of cancer deaths are accredited to lung cancer and that cigarette smoking is the number one cause of lung cancer, other forms of cancer, and cancer deaths worldwide (1). Second hand smoke is also a very serious health concern. Second hand smoke has been chosen as a cancer-causing agent by the U.S. Environmental Protection Agency, the National Toxicology Program and the International Agency for Research on Cancer …


Assessment Of The Reliability Of The Diagnosis Of Chagas Disease By Indigenous Promotores Of The Amazon Basin In Ecuador, Summer Nguyen Aug 2009

Assessment Of The Reliability Of The Diagnosis Of Chagas Disease By Indigenous Promotores Of The Amazon Basin In Ecuador, Summer Nguyen

Undergraduate Medical Student Research

Chagas disease, caused by the protozoan parasite, Trypanosoma cruzi, is the most important vector-borne disease in Latin America. It is estimated that 16 to 18 million people are infected with Chagas disease and some 50,000 people die each year. In endemic countries, people living in rural areas are at greatest risk for acquiring infection. Ecuador is one of these countries, and it is estimated that between 2.4-3.8 million people in Ecuador are exposed to Chagas disease, primarily in the Eastern endemic coastal region. The indigenous people of the Amazon region in Ecuador have historically been protected from Chagas disease due …


Tapping In Time: Visual And Auditory Selective Attention In Schizophrenia, Irene Patniyot Aug 2009

Tapping In Time: Visual And Auditory Selective Attention In Schizophrenia, Irene Patniyot

Undergraduate Medical Student Research

Attention is a complex construct involving extensive interactions with working memory and executive control systems to process and extract meaning out of large amounts of multi-sensory information. Disruption of attention is a characteristic symptom in schizophrenia, and further studies on selective attention are crucial for understanding the disease. The current study looks at how subjects with schizophrenia selectively attend to either a visual or auditory metronome in the presence of asynchronous cross-modal distractors of 3 different frequencies (0.5, 1, and 2 Hz). Results showed that across all tasks of selective attention, patients with schizophrenia demonstrated increased variability in mean group …


West Nile Disease In New Mexico: The Quest For Nucleic Acid, Randin Nelson, Robert Nofchissey, Diane Goade Aug 2009

West Nile Disease In New Mexico: The Quest For Nucleic Acid, Randin Nelson, Robert Nofchissey, Diane Goade

Undergraduate Medical Student Research

West Nile virus (WNV) was first detected in New Mexico in 2002, with the first human cases appearing in 2003. Since that time it has become endemic in the region, and as of year-end 2005, 330 New Mexicans had been diagnosed with West Nile Fever or the more severe neuroinvasive disease as reported by the New Mexico Department of Health. An ongoing study at the University of New Mexico has collected interview and physical exam data for these individuals as well as collecting cerebrospinal fluid (CSF) and serum from their period of acute and convalescent illness. While all of these …


Health Care Utilization Pilot Study: Recruiting And Interviewing Residents Of The South Valley, Irma Mariana Santiago, Mariana Mejia Botero Aug 2009

Health Care Utilization Pilot Study: Recruiting And Interviewing Residents Of The South Valley, Irma Mariana Santiago, Mariana Mejia Botero

Undergraduate Medical Student Research

Although research nationwide has shown that health care utilization amongst undocumented immigrants is substantially lower than U.S. citizens, the former are often blamed for the inadequacies of our health care system. In order to test whether utilization patterns amongst undocumented immigrants in our own city of Albuquerque coincide with current data, we first needed to determine the best recruitment methods for identifying undocumented immigrants. This pilot project tested three commonly used methods in survey research: 1) in-person household surveys (from here on referred to as canvassing), 2) RDD telephone survey (from here on referred to as calling) and 3) a …


Native American Juvenile Detainees In New Mexico: A Descriptive Study Of Gender Differences, Mental And Behavioral Health Conditions, And Social Risk Factors, Aaron Price Aug 2009

Native American Juvenile Detainees In New Mexico: A Descriptive Study Of Gender Differences, Mental And Behavioral Health Conditions, And Social Risk Factors, Aaron Price

Undergraduate Medical Student Research

Risk factors for juvenile detention vary by gender but, in general, include low household income, individual and family histories of mental and behavioral disorders, sexual and physical abuse, low academic achievement/academic difficulty, and ethnic/racial minority status. In New Mexico, a number of these risk factors characterize the lives of Native American youth. However, the prevalence of and relationships among risk factors for detained Native American juveniles is unknown. Moreover the lack of data has impeded community-based mental and behavioral health treatment and prevention efforts meant to decrease destructive behavior and prevent initial or subsequent detention or incarceration.


Smokeless Tobacco Prevalence In Roswell, New Mexico, Marianne Berwick, Willie Nunez, Josh Raiten Aug 2009

Smokeless Tobacco Prevalence In Roswell, New Mexico, Marianne Berwick, Willie Nunez, Josh Raiten

Undergraduate Medical Student Research

The purpose of this study is to determine the prevalence of smoking and smokeless tobacco use in an un-surveyed region of New Mexico. The reason for doing this is because the recent information of smoking and smokeless tobacco use in the state of New Mexico is incomplete, specifically in the Roswell area. This information is needed in order to understand the association between smokeless tobacco use and oral cancer, stroke, and cardiovascular disease. There are also questions of whether people are stopping smoking and switching to smokeless tobacco as well as the possibility that using smokeless tobacco could lead to …


Conceptions Of Contraception: Awareness And Access To Emergency Contraception Among Young Adults In Albuquerque, Almea Matanock Aug 2009

Conceptions Of Contraception: Awareness And Access To Emergency Contraception Among Young Adults In Albuquerque, Almea Matanock

Undergraduate Medical Student Research

Background: Family planning has enormous societal, economic, and interpersonal implications. The United States, NM is no exception, has a much higher rate of unintended pregnancies (50%) than other developed countries. This is associated with poor health outcomes for the mother and the child. Emergency contraception (EC) provides a safe back up method. NM had tried to increase access to EC by licensing pharmacists to dispense it without a prescription. In addition, the FDA agreed to make it OTC for people >18 years old. Objective: To assess young adults knowledge and access to EC in the Albuquerque area. Our goal is …


Development Of A Potential Vaccine For Asthma Using Ige And Virus Like Particles, Fernando Monreal, Bryce Chackerian Aug 2009

Development Of A Potential Vaccine For Asthma Using Ige And Virus Like Particles, Fernando Monreal, Bryce Chackerian

Undergraduate Medical Student Research

Highly dense, repetitive antigens such as virus particles induce strong immune responses. Correspondingly, Virus Like Particles (VLPs), which consist of the viral structural proteins, can be used as molecular scaffolds to increase the antigenicity of normally poorly immunogenic antigens. This ability to elicit strong antibody responses is not limited to foreign antigens, but also to self-antigens, which are normally subject to B-cell tolerance. The intention of this proposal is to develop a system for rapid identification of asthma vaccine candidates based on potent immunogenicity of antigens (IgE) displayed in dense repetitive arrays on virus-like particles. The technology is based on …


Number Of Nevi And Survival With Melanoma, Kathleen Lopez, Michael Reyes, Marianne Berwick, Susan Paine Aug 2009

Number Of Nevi And Survival With Melanoma, Kathleen Lopez, Michael Reyes, Marianne Berwick, Susan Paine

Undergraduate Medical Student Research

Possession of a higher than average number of nevi has long been substantiated as one of several factors that predispose patients to malignant melanoma. Despite the relative certainty of this relationship, little is known about the relationship between the number of nevi a person possesses and risk of death from melanoma. A cohort of melanoma patients was followed prospectively to determine if a significant relationship exists between number of nevi and increased mortality from melanoma. Age at diagnosis, melanoma of the head and neck, increasing Breslow thickness and presence of mitoses all were associated with poorer survival in our multivariate …


Efficacy Of Bisphosphonates In The Treatment Of Low Bone Density In The Pediatric Population, Christopher Loucks, Elizabeth Szalay Aug 2009

Efficacy Of Bisphosphonates In The Treatment Of Low Bone Density In The Pediatric Population, Christopher Loucks, Elizabeth Szalay

Undergraduate Medical Student Research

Low bone density for age is becoming an increasingly recognized problem in the pediatric world. It can be a very tricky condition to properly diagnose and treat. Current treatment guidelines maintain that bisphosphonates are a last resort therapy and are not currently FDA approved for pediatric use. There is data available that supports the use of these agents in children for the treatment of low bone density, as well as secondary benefits, i.e. decreased incidence of insufficiency fractures. However, the majority of the studies includes small population sizes, they are not randomized, or are not compared to a control group. …


Obesity Doesn't Make Breast Hot Or Blue, Anne Marie Wallace, S.T. Anthony Kaviratne, Sang-Joon Lee Aug 2009

Obesity Doesn't Make Breast Hot Or Blue, Anne Marie Wallace, S.T. Anthony Kaviratne, Sang-Joon Lee

Undergraduate Medical Student Research

Background: Sentinel lymph node (SLN) mapping and biopsy have become the standard of care for axillary staging of a breast cancer patient. Higher rate of use has led to the identification of an absolute failure rate and a subset of patients who fail lymph node mapping due to causes independent of the procedure. Failure of lymph node mapping leads to more invasive procedures with higher morbidity. Body mass index has been associated with higher SLN failure rate. Methods: Retrospective study of patients who underwent Sentinel lymph node procedures between October 2003 to June 2008 at University of New Mexico. After …


Ultrasound Guided Sciatic Nerve Blockage In The Popliteal Fossa Using A Lateral Approach: Onset Time Comparing Separate Tibial And Common Peroneal Nerve Injections Vs. Single Injection Proximal To The Bifurcation, Anna Hoard, Michael Buys Aug 2009

Ultrasound Guided Sciatic Nerve Blockage In The Popliteal Fossa Using A Lateral Approach: Onset Time Comparing Separate Tibial And Common Peroneal Nerve Injections Vs. Single Injection Proximal To The Bifurcation, Anna Hoard, Michael Buys

Undergraduate Medical Student Research

The popliteal nerve block can be performed either proximal to the bifmcation of the sciatic nerve, or distal to the bifmcation, thus blocking both the common peroneal and tibial nerves. Studies have shown equal success rates when comparing the two methods. The purpose of this investigation is to determine if blocking the tibial and common peroneal nerves individually in the popliteal fossa under ultrasound guidance will result in a faster onset time to smgical anesthesia when compared to blocking the sciatic nerve proximal to the bifurcation under ultrasound guidance. A total of 56 patients who underwent foot surgery were randomized …


Airway Management Experience Of Rural Physicians In New Mexico And The Impact Of Atls: A Descriptive Study, Craig Lehrman Aug 2009

Airway Management Experience Of Rural Physicians In New Mexico And The Impact Of Atls: A Descriptive Study, Craig Lehrman

Undergraduate Medical Student Research

The management of trauma revolves around the ABCDEs; standing for airway,breathing, circulation, disability (neurological status), and exposure or environmental control, and are attended to in that order [1]. This acronym is a primary survey method for assessing a trauma patient to identify any potential life-threatening conditions that may be present. Attaining and maintaining an airway is an essential step in the management of any trauma patient and failure to do so results in drastically increased morbidity and mortality. There is such a vast array of techniques and complicating factors that getting past the first two steps of A (airway) and …


Are Urinary Catheters Necessary During Endovascular Procedures? A Prospective Randomized Pilot Study, Jordan Knepper Aug 2009

Are Urinary Catheters Necessary During Endovascular Procedures? A Prospective Randomized Pilot Study, Jordan Knepper

Undergraduate Medical Student Research

The use of urethral catheterization in surgery can trace its root to 19th century military surgeons utilizing them to prevent urinary retention after morphine use, and to minimized complications after spinal cord injury [1]. It has become a common surgical practice to place urinary catheters in patients during many interventions [2, 3]. This practice has little support in evidence based literature [4, 5]. In theory a urinary catheter is place to drain the bladder and avoid complications such as over dilatation of the bladder which may result in dystonia [2, 6]. These complications are not well demonstrated in their occurrence …


Clinical Characteristics Of Niemann Pick Type C In New Mexican Patients, Jayme Heath Aug 2009

Clinical Characteristics Of Niemann Pick Type C In New Mexican Patients, Jayme Heath

Undergraduate Medical Student Research

Object. The authors review 11 known cases of Niemann Pick type C (NPC) in New Mexican patients to better characterize the natural history and disease progression in these patients. Methods. The authors performed a retrospective review of data obtained from eleven patients with NPC seen in the Division of Pediatric Neurology at the University of New Mexico, Albuquerque, New Mexico. These patients attended routine follow up examinations conducted by a number of specialists to monitor disease progression. Conclusions. The New Mexican cohort of NPC patients displayed an earlier age of onset, increased prevalence of vertical supranuclear gaze palsy as compared …


Supporting The Use Of Mbd-1 Knockout Mice As An Animal Model For Autism, Laura Heise, Andrea Allan Aug 2009

Supporting The Use Of Mbd-1 Knockout Mice As An Animal Model For Autism, Laura Heise, Andrea Allan

Undergraduate Medical Student Research

OBJECTIVES: The prevalence of autism in our society has grown over the past few decades while lack of a central pathophysiological cause for the disease has hindered research and design of an animal model with the disease. Methyl CpG Binding Domain-1 knockout mice are a potential model for autism. The mice are owned soley by Dr. Xinyu Zhao of the University of New Mexico. The mice appear normal, both anatomically and developmentally, however, they exhibit behaviors that are often seen in autistic patients. While there are few specific physiological hallmarks of autism among patients, a few studies have noted increased …


Spinal Anesthesia For Post Partum Tubal Ligation: A Comparison Of Lidocaine Vs. Meperidine, Chelsea Hinkle, Frank Jaime, Eva Szabo, Nancy Morgan, Mark Wilson, Arpad Zolyomi Aug 2009

Spinal Anesthesia For Post Partum Tubal Ligation: A Comparison Of Lidocaine Vs. Meperidine, Chelsea Hinkle, Frank Jaime, Eva Szabo, Nancy Morgan, Mark Wilson, Arpad Zolyomi

Undergraduate Medical Student Research

Short acting neuraxial local anesthetic, lidocaine, has been a popular choice for providing surgical anesthesia for short duration surgical procedures such as post partum tubal ligation (PPTL). Meperidine is a narcotic that also has local anesthetic properties, thus provides both anesthesia and analgesia. Previous studies have shown meperidine to shorten post anesthesia care unit (PACU) stays when compared to lidocaine for neuraxial spinal anesthesia. These studies were done using variable dosing of meperidine and lidocaine based on height. This study compares lidocaine to meperidine at a standard dose of 75 mg for each in regards to the following; onset of …


A Prospective, Controlled Trial Of A Pharmacy-Driven Alert System To Increase Thromboprophylaxis Rates In Medical Inpatients, Jessica Highfill, David Garcia, Katie Finnerty, Keith Hutchinson Aug 2009

A Prospective, Controlled Trial Of A Pharmacy-Driven Alert System To Increase Thromboprophylaxis Rates In Medical Inpatients, Jessica Highfill, David Garcia, Katie Finnerty, Keith Hutchinson

Undergraduate Medical Student Research

Background: Although venous thromboembolism is an important cause of morbidity and mortality within the hospital, a significant proportion of at-risk inpatients do not receive measures known to reduce the risk of deep vein thrombosis and pulmonary embolism. Objective: To determine whether a pharmacy driven alert system would, compared to usual care, be associated with a higher rate of adequate VTE prevention measures among at-risk inpatients on a general internal medicine service. Design: Prospective, controlled trial. Setting: A university-based teaching hospital. Patients: Adults admitted (Monday through Friday) to the general internal medicine inpatient service from 6/19/06-9/21/06. Intervention: Pharmacist assessment of venous …