Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Entire DC Network
Fetal Alcohol Spectrum Disorder-Associated Depression: Evidence For Reductions In The Levels Of Brain-Derived Neurotrophic Factor In A Mouse Model, Kevin Caldwell, S. Sheema, Rodrigo D. Paz, Sabrina Samudio-Ruiz, Mary Laughlin, Nathan Spence, Michael Roehlk, Sara Alcon, Andrea Allan
Fetal Alcohol Spectrum Disorder-Associated Depression: Evidence For Reductions In The Levels Of Brain-Derived Neurotrophic Factor In A Mouse Model, Kevin Caldwell, S. Sheema, Rodrigo D. Paz, Sabrina Samudio-Ruiz, Mary Laughlin, Nathan Spence, Michael Roehlk, Sara Alcon, Andrea Allan
Undergraduate Medical Student Research
Prenatal ethanol exposure is associated with an increased incidence of depressive disorders in patient populations. However, the mechanisms that link prenatal ethanol exposure and depression are unknown. Several recent studies have implicated reduced brain-derived neurotrophic factor (BDNF) levels in the hippocampal formation and frontal cortex as important contributors to the etiology of depression. In the present studies, we sought to determine whether prenatal ethanol exposure is associated with behaviors modeling depression, as well as with reduced BDNF levels in the hippocampal formation and/or medial frontal cortex, in a mouse model of fetal alcohol spectrum disorder (FASD). Compared to control adult …
Postmortem Analysis Of Synovial Fluid: An Alternative Method For Determining The Presence Of Ethanol, Katie Forman, David Meredith
Postmortem Analysis Of Synovial Fluid: An Alternative Method For Determining The Presence Of Ethanol, Katie Forman, David Meredith
Undergraduate Medical Student Research
Postmortem toxicological analysis is often an important tool in autopsy in determining the cause of death. There are circumstances however when traditional samples such as blood and vitreous fluid are unobtainable. In such instances, alternative body fluids such as synovial fluid may be useful adjuncts. However, synovial fluid has not been accepted as a widely used alternative. The purpose of this study was to determine the correlation between blood ethanol content and synovial fluid ethanol content. To this end, synovial fluid was obtained from 98 cases presenting to the Office of the Medical Investigator in Albuquerque, New Mexico over a …