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The Neuroendocrine And Performance Correlates Of Posttraumatic Stress Disorder In Males And Females, Meghan E. Pierce
The Neuroendocrine And Performance Correlates Of Posttraumatic Stress Disorder In Males And Females, Meghan E. Pierce
UNLV Theses, Dissertations, Professional Papers, and Capstones
Distinct gender differences exist in the incidence of posttraumatic stress disorder in the United States population. Currently, the direct biological mechanisms involved in the development of PTSD have not been elucidated. However, many studies indicate a dysregulation of the hypothalamic-pituitary-adrenal axis (HPA-axis) as a contributing factor in the development of PTSD. This study investigated performance and endocrine correlates of PTSD in 38 females without PTSD, 14 females with PTSD, 32 males without PTSD and 5 males with PTSD. We examined the differences between basal cortisol concentrations, as well as cortisol reactivity to the Trier Social Stress Test (TSST). In addition, …