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The Effects Of Mushroom Body Lobe Disruption On Learning And Memory, Brian S Dunkelberger
The Effects Of Mushroom Body Lobe Disruption On Learning And Memory, Brian S Dunkelberger
UNLV Retrospective Theses & Dissertations
Animal models have been used for centuries to study learning and memory in simple systems with many applications to humans (Chapter 1). The fruit fly Drosophila melanogaster has added greatly to our current understanding of learning and memory and its underlying biology (Chapter 2). The research described here focuses on the relationship between learning and memory and the brain using three mutant strains of flies: mushroom body miniature B (mbmB), small mushroom bodies (smu), and mushroom bodies reduced (mbr). Mushroom bodies are paired neuronal structures found in most invertebrate brains involved in learning and memory consolidation. All three mutations studied …
The Neurocognitive Impairment Associated With Comorbid Schizophrenia And Ptsd, Lisa Duke
The Neurocognitive Impairment Associated With Comorbid Schizophrenia And Ptsd, Lisa Duke
UNLV Retrospective Theses & Dissertations
Individuals with severe mental illness report a higher incidence of trauma and PTSD than the general population. A trauma history in individuals with schizophrenia has been associated with more severe psychiatric symptoms including positive symptoms, depression, suicidality, anxiety, somatization and dissociation (Beck & van der Kolk, 1987; Craine, Henson, Colliver & MacLean, 1988; Ross, Anderson & Clark, 1994; Darves-Bornoz, & Gaillard, 1995; Holowka, King, Saheb, Pukall & Brunett, 2003; Strauss et al., 2006); The current study is among the first to examine the influence of comorbid schizophrenia and PTSD by performing comprehensive diagnostic, symptom and neurocognitive evaluations on four groups: …
How Subjective And Objective Memory, Family History, And Knowledge Of Alzheimer's Disease Influence Older Adults' Fear Of Developing Alzheimer's Disease, Samantha Lyn French
How Subjective And Objective Memory, Family History, And Knowledge Of Alzheimer's Disease Influence Older Adults' Fear Of Developing Alzheimer's Disease, Samantha Lyn French
UNLV Retrospective Theses & Dissertations
It is projected that by the year 2050, the number of Americans with Alzheimer's disease (AD) will rise to approximately 13.2 million. And, because AD is on the rise, apprehension about developing the degenerative disease (anticipatory dementia or fear of developing AD) has become a topic of study in the past few years. However, most studies focusing on anticipatory dementia have used a sample of individuals younger than age 65 and have used a single item questionnaire to explore their apprehension. The current study utilized 50 adults ages 65 and older to examine anticipatory dementia and its relationship with subjective …
Working Memory Deficits In Psychotic Bipolar Disorder: Trait Marker For Psychosis, Carol Randall
Working Memory Deficits In Psychotic Bipolar Disorder: Trait Marker For Psychosis, Carol Randall
UNLV Retrospective Theses & Dissertations
There is significant overlap in the symptom presentation and cognitive impairment found in individuals with bipolar disorder with psychotic features and in those with some subtypes of schizophrenia. Due to this overlap, debate regarding the existence and nature of a relationship between these disorders has been an ongoing and complicated one. Some continue to view these disorders as they are conceptualized in the current psychiatric diagnostic manual, as distinct and categorical in nature. Others have proposed an "affective-psychotic spectrum" with schizophrenia lying at one end of this spectrum, non-psychotic affective disorders lying at the opposite end of the spectrum, and …