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Uneven Distribution Of Mhc Class Ii Epitopes Within The Influenza Virus, Sherry R. Crowe, Shannon C. Miller, Pamela S. Adams, Richard Dutton, Allen G. Harmsen, Frances E. Lund, Troy D. Randall, Deborah M. Brown, Susan Swain, David L. Woodland

Nebraska Center for Virology: Faculty Publications

The identification of T cell epitopes is crucial for the understanding of the host immune response during infection. While much is known about the MHC class I-restricted response following influenza virus infection of C57BL/6 mice, with over 16 CD8 epitopes identified to date, less is known about the MHC class II-restricted response. Currently, only a few I-A^b-restricted T helper epitopes have been identified. Therefore, several important questions remain about how many class II epitopes exist in this system and whether these epitopes are evenly distributed within the most abundant viral proteins. In order to address these questions, we …

Influenza Vaccination Coverage Of Children Aged 6 To 23 Months: The 2002–2003 And 2003–2004 Influenza Seasons, Tammy A. Santibanez, Jeanne M. Santoli, Carolyn B. Bridges, Gary L. Euler

Public Health Resources

BACKGROUND. Beginning in 2002 the Advisory Committee on Immunization Practices

encouraged, when feasible, annual influenza vaccination of all children aged 6 to

23 months and household contacts and out-of-home caregivers of children <2

years of age.

OBJECTIVE.We sought to report influenza vaccination coverage for the 2002–2003

and 2003–2004 influenza seasons among children aged 6 to 23 months according

to demographic and immunization-provider characteristics.

METHODS. Data from the 2003 and 2004 National Immunization Survey were analyzed.

Two measures of childhood influenza vaccination are reported: receipt of

>1 influenza vaccination and full vaccination (ie, receipt of the appropriate

number of doses on the …