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Evaluating Executive Functions In A Proposed Animal Model Of Adhd: Spontaneously Hypertensive Rats, Joshua Lee Potter
Evaluating Executive Functions In A Proposed Animal Model Of Adhd: Spontaneously Hypertensive Rats, Joshua Lee Potter
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Evaluating animal models of attention-deficit hyperactivity disorder (ADHD) is crucial for expanding the breadth of knowledge of the disorder. Spontaneously Hypertensive Rats (SHRs) have been used for several years as an animal model of ADHD, and routinely provide new information about aspects of the disorder that contribute to behavioral and pharmaceutical treatment interventions. Twelve male and 12 female SHRs as well as 12 male and 12 female Wistar-Kyoto rats (i.e., control strain for the SHR) were acquired and tested on a series of operant tests starting postnatal day (PND) 70. These tests consisted of measures of motor and executive function …