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The Consolidation Of Memory Associations, Kyle A. Kainec Aug 2023

The Consolidation Of Memory Associations, Kyle A. Kainec

Doctoral Dissertations

Creating memories is a fundamental challenge for the human brain. To create memories, defining features of experiences must be stored distinguishably without forgetting other memories. Memory associations represent co-occurring features and defining features across experiences. Memory associations are represented as networks of information that are stored in the brain. New memory associations are encoded during experiences and can be used to update existing memory associations during offline intervals. However, the mechanisms that underlie how encoded memory associations are stored within existing networks during offline intervals remains unclear. The experiments in this dissertation address a significant theoretical gap in understanding the …


Characterizing The Roles Of The Variable Linker And Hub Domains In Camkii Activation, Noelle Dziedzic Feb 2023

Characterizing The Roles Of The Variable Linker And Hub Domains In Camkii Activation, Noelle Dziedzic

Doctoral Dissertations

Learning and memory formation at the cellular level involves decoding complex electrochemical signals between nerve cells, or neurons. Understanding these processes at the molecular level requires a comprehensive study of calcium-sensitive proteins that serve as signal mediators within cells. More specifically, the protein calcium/calmodulin-dependent protein kinase II (CaMKII) is a key regulator of downstream cellular signaling events in the brain, playing an important role in long term memory formation. CaMKII is encoded in humans on four different genes: alpha, beta, gamma and delta. For added complexity, each of these gene products can be alternatively spliced and translated into multiple protein …


Changing Criteria: What Decision Processes Reveal About Confidence In Memory, Johanny N. Castillo Oct 2022

Changing Criteria: What Decision Processes Reveal About Confidence In Memory, Johanny N. Castillo

Masters Theses

Source memory is our ability to relate central information (the “item”) to the context (the “source”) in which it was learned or experienced. People are often highly confident in their source judgements even when this information is incorrectly recalled. Past work has aimed to explain why source errors made with high confidence occur with a framework called the Converging Criteria (CC) account. The CC account posits that item memory can interact with source memory by altering decision criteria as item confidence increases, increasing the probability of a high confidence source judgement. This prediction differs from alternate models, like the Fixed …


The Role Of Autobiographical Memory Recall In Reappraisal Efficacy And Effort Across Age, Irina Orlovsky Oct 2022

The Role Of Autobiographical Memory Recall In Reappraisal Efficacy And Effort Across Age, Irina Orlovsky

Masters Theses

Socioemotional theories posit that the experience of overcoming unique life challenges over a lifetime enhances self-efficacy and emotional resilience among older adults. Older adults demonstrate greater emotional well-being and motivation to regulate emotions than younger adults, but specific regulatory mechanisms supporting late-life emotional resilience remain unclear. Cognitive reappraisal is an effective but cognitively demanding emotion regulation strategy and shows mixed efficacy in later-life. While a growing repertoire of autobiographical memories may be a resource with age, the role of autobiographical recall in momentary reappraisal has never been tested empirically. In this online study, older and younger adults were trained to …


There And Gone Again: Syntactic Structure In Memory, Caroline Andrews Apr 2021

There And Gone Again: Syntactic Structure In Memory, Caroline Andrews

Doctoral Dissertations

This dissertation addresses the relationship between hierarchical syntactic structure and memory in language processing of individual sentences. Hierarchical syntactic structure is a key part of human languages and language processing but its integration with memory has been uneasy ever since Sachs (1967) demonstrated that the syntactic structure of individual sentences is lost in explicit sentence recall tasks much faster than other linguistic information (lexical, semantic, etc.). Nonetheless, psycholinguists have continued to draw on memory in syntactic processing theories, in part due to (i) the explanatory power that memory can give to sentence processing hypotheses, and (ii) the conflicting results that …


Slow Wave Sleep In Naps Supports Episodic Memories In Early Childhood, Sanna Lokhandwala Apr 2021

Slow Wave Sleep In Naps Supports Episodic Memories In Early Childhood, Sanna Lokhandwala

Masters Theses

Naps have been shown to benefit declarative memories in early childhood. This benefit has been associated with sleep spindles during the nap. However, whether young children’s naps and their accompanying physiology benefit other forms of declarative learning is unknown. Using a novel storybook task, we found performance was better following a nap compared to performance following an equivalent interval spent awake. Moreover, performance was better the following day if a nap followed learning. Further, change in post-nap performance was positively associated to the amount of time spent in slow wave sleep. This suggests that slow wave sleep in naps may …


A Genealogy Of Victimhood: Empathy And Memory In Recent German Fiction, Catherine E. Mcnally Dec 2020

A Genealogy Of Victimhood: Empathy And Memory In Recent German Fiction, Catherine E. Mcnally

Doctoral Dissertations

This dissertation addresses literary representations of empathy and altruism in Jenny Erpenbeck’s 2015 novel Gehen, Ging, Gegangen and Bodo Kirchhoff’s 2016 novel Widerfahrnis. These novels demonstrate continuities and discontinuities between German literature of the postwar, reunification and contemporary contexts.Analyzing expressions of empathy by Erpenbeck and Kirchhoff’s protagonists, I locate them in historical and literary contexts, the roots of which can be traced to the first generation of postwar German literature (1945-1968), particularly Heinrich Böll and Günter Grass. In both Grass and Böll’s early postwar fiction, German experiences of the war and its aftermath are foregrounded, and focus is placed …


Defining The Let-7 Microrna-Mediated Molecular Mechanisms Regulating T Cell Differentiation, Constance C. Angelou May 2020

Defining The Let-7 Microrna-Mediated Molecular Mechanisms Regulating T Cell Differentiation, Constance C. Angelou

Doctoral Dissertations

CD4+ and CD8+ T cells are lymphocytes of the adaptive immune system that play essential roles in immunity. Both T cell subsets recognize their cognate antigen through the T cell receptor (TCR), which induces the proliferation and differentiation of these antigen-specific cells into effector T cells. CD4+ T cells have the potential to differentiate into one of multiple lineages of helper T (Th) cells and participate indirectly in antigen clearance by orchestrating the function of other cells. CD8+ T cells differentiate into cytotoxic T lymphocytes (CTL), which directly contributes to the resolution of an infection by …


Testing The Convergent Retrieval Learning Theory Of Testing Effects, William J. Hopper Mar 2020

Testing The Convergent Retrieval Learning Theory Of Testing Effects, William J. Hopper

Doctoral Dissertations

What is learned from retrieving a memory that is not learned by studying the same information? In response to this question, I have proposed a new theory of retrieval-based learning in which I argue that retrieval strengthens the ability to completely activate all portions of a memory trace from an initial state of partial activation. In effect, retrieval serves to unitize the features of a memory, making the entire memory remain retrievable in the future when cue-related activation may be weaker. This theory, called the Primary and Convergent Retrieval (PCR) model, explains why practice tests produce both better long-term retention …


The Political Work Of Memory In Collaborative Caribbean Archaeology, Elena Sesma Jul 2019

The Political Work Of Memory In Collaborative Caribbean Archaeology, Elena Sesma

Doctoral Dissertations

This dissertation is the product of a community-based research project that sought to understand how descendants of the 19th century Millars Plantation on the southern end of Eleuthera, Bahamas continue to use and reinterpret the landscape that they have called home for over a century and a half. In 1871, the last owner of the Millars Plantation left the estate in her will to the descendants of her former slaves and servants. That descendant community still upholds their right to this land today, although in recent years, a Bahamian developer has attempted to gain title to the acreage through the …


Hashtag Holocaust: Negotiating Memory In The Age Of Social Media, Erica Fagen Jul 2019

Hashtag Holocaust: Negotiating Memory In The Age Of Social Media, Erica Fagen

Doctoral Dissertations

This study examines the representation of Holocaust memory through photographs on the social media platforms of Flickr and Instagram. It looks at how visitors – armed with digital cameras and smartphones – depicted their experiences at the former concentration camps of Auschwitz-Birkenau, Dachau, Sachsenhausen, and Neuengamme. The study’s arguments are twofold: firstly, social media posts about visits to former concentration camps are a form of Holocaust memory, and secondly, social media allows people from all backgrounds the opportunity to share their memories online. Holocaust memory on social media introduces a new, digital kind of memory called “filtered memory.” This study …


Recollections: Memory, Materiality, And Meritocracy At The Dr. James Still Historic Office And Homestead, Marc Lorenc Jul 2019

Recollections: Memory, Materiality, And Meritocracy At The Dr. James Still Historic Office And Homestead, Marc Lorenc

Doctoral Dissertations

The dissertation explores how memory, materiality, and meritocracy articulate together to create a meritocratic subjectivity at the Dr. James Still Historic Office and Homestead. This subjectivity frames how we experience and promote the history of Dr. James Still through an authorized heritage discourse (AHD) (Smith 2006) that promotes and re-ingrains American meritocracy, specifically the “bootstrap myth”, as a “common sense”. Using a combination of archaeological excavations, documentary analysis, and ethnography conducted under the Dr. James Still Community Archaeology Project (DJSCAP), I explore how cultural artifacts shape and influence our subjectivities at the site and more broadly in everyday interactions with …


Let-7 Mirnas Program The Fate Of Cd8 T Cells, Alexandria Wells Jul 2019

Let-7 Mirnas Program The Fate Of Cd8 T Cells, Alexandria Wells

Doctoral Dissertations

CD8 T cells are the cytotoxic effectors of the adaptive immune response, clearing virally infected and cancerous cells within the host. CD8 T cells acquire their cytotoxic function by differentiating into cytotoxic T lymphocytes (CTLs). Once the CTLs have cleared the antigen, the majority of responding cells will die during contraction; however, a small population of the antigen-specific responders will remain, differentiating into long-lived memory cells that provide potent protection to the host upon re-encounter with the antigen. These differentiation programs often become disturbed in cases of chronic infection and cancer. Instead, CD8 T cells are subverted into the so-called …


(Re)Developing Place: The Power Of Narrative, Kinsey Diomedi Jul 2019

(Re)Developing Place: The Power Of Narrative, Kinsey Diomedi

Masters Theses

Architectural space is a manifestation of human memory and experiences. It is a physical indicator of time and history, and it provides a canvas for us to imagine the future. Architecture anchors people in a moment in time and space, while also embodying the past and implying a future. It is not just a monument to time, but what has happened during that time; a collection of past human experiences and what will yet happen. Architecture is the manifestation of our stories, our lives. The more visually present these stories are in architecture, the richer the canvas, and the more …


Remains To Be Seen: Recollecting Memory, Nathanael Kooperkamp Oct 2018

Remains To Be Seen: Recollecting Memory, Nathanael Kooperkamp

Masters Theses

Abstract

Remains to be Seen, a multi-media installation, provides the opportunity for reconfiguration, re-contextualization and re-remembering of visual memory. Geoffry Cubit, a historian of memory, has noted that “memory has no fixed, stable, unitary meaning to which we can invariably recur: it has always been, and legitimately, a concept in flux and under review”.[1]My work in this exhibition (and as discussed throughout this paper) addresses the unstable and revisionist nature of memory—both culturally and individually. Additionally, I attempt to address how memory (collective, visual, familial and individual) is implicated in the creation of selfhood, of personal narrative, …


Assessing The Long-Term Sequelae Of Mild Traumatic Brain Injury, Janna Mantua Mar 2018

Assessing The Long-Term Sequelae Of Mild Traumatic Brain Injury, Janna Mantua

Doctoral Dissertations

A mild traumatic brain injury (mTBI), also known as a concussion, is defined as an injury that results in an alteration of consciousness or mental status. Previous studies have shown mTBI populations experience a number of chronic (> 1 year) symptoms, such as sleep disturbances (e.g., sleep stage alterations), mood alterations (e.g., depressive symptoms), and cognitive alterations (e.g., poor concentration). The three chapters of this dissertation sought to explore these long-term sequelae and the possible interrelations between them. In the first experiment, sleep-dependent memory consolidation of neutral stimuli was probed in a chronic mTBI sample and a control, uninjured sample. …


Fantasy Frontier: Old West Theme Parks And Memory In California, Amanda Tewes Nov 2017

Fantasy Frontier: Old West Theme Parks And Memory In California, Amanda Tewes

Doctoral Dissertations

This study examines sites of Old West tourism—specifically the three California theme parks of Knott’s Berry Farm, Calico Ghost Town, and Frontier Village—as avenues through which the myth of “the West” gets propagated, even among the people of the American West, and even if these sites do not reflect the actual history of the region. California’s Old West theme parks act as windows into mid-twentieth-century cultural conflicts of politics and identity within the state. But these sites are artifacts of a particular historical moment and their fantasy of the Old West memorializes mid-century renderings of the past rather than nineteenth-century …


Conformity And Digression: Change Of Narrative In A Chinese Peasant's Personal Writing, Danping Wang Jul 2017

Conformity And Digression: Change Of Narrative In A Chinese Peasant's Personal Writing, Danping Wang

Masters Theses

Rural China has gone through dramatic transformation from the Mao era to the post-Mao era. China scholars have been studying the institutional changes closely in the past few decades. However, Chinese peasants’ living experience and their memory and understanding of the past have not yet received enough attention and discussion. By examining personal writings of a peasant named Luo Xuechang in Jiande, Zhejiang province, this paper discusses the complex interactions between the state and the individual. This paper attempts to unfold the juxtaposition of state narratives and personal narratives embedded in Luo’s unpublished memoir, almanacs from 1972 to 1980, notebooks …


The Unaccustomed Vanishing Point, Procheta Olson Jul 2017

The Unaccustomed Vanishing Point, Procheta Olson

Masters Theses

The Unaccustomed Vanishing Point is an exhibition of miniature paintings and installations that explore the irregular and fluid terrains of multicultural exchanges in India. Although drawing heavily from Mughal and Persian painting traditions, the paintings are rife with allegories of the postcolonial history, politics, and visual and material culture of contemporary India in the age of globalization. The installations, on the other hand, navigate the intersection of sensory experience and memory while simultaneously examining the dynamics of transnational experiences. Together they map the overlapping boundaries of the personal and social to probe into the complex interplay of cultural hybridity, class, …


A Visible History: A Synthesis Of Past, Present And Future Through The Evocation Of Memory Within Historic Contexts, Nicholas Jeffway Jul 2017

A Visible History: A Synthesis Of Past, Present And Future Through The Evocation Of Memory Within Historic Contexts, Nicholas Jeffway

Masters Theses

How can new spaces evoke the layers of memory associated with historic places and utilize them to envision anew? What are the spatial strategies involved with creating architecture rich in memory and how can a space which is cognizant of its physical and historical context serve as a tool for revitalization?

These questions could be used to investigate revitalization efforts in much of the cities and towns which line the Connecticut River Valley. Ultimately, solutions become directly rooted in the context to which they are set.

With the industrial village of Turners Falls as the setting, this thesis is based …


"The Fate Which Takes Us:" Benjamin F. Beall And Jefferson County, (West) Virginia In The Civil War Era, Matthew Coletti Mar 2016

"The Fate Which Takes Us:" Benjamin F. Beall And Jefferson County, (West) Virginia In The Civil War Era, Matthew Coletti

Masters Theses

This thesis analyzes the editorial content of a popular regional newspaper from the Shenandoah Valley, the Spirit of Jefferson, during the height of the Civil-War Era (1848-1870). The newspaper’s editor during most of the period, Benjamin F. Beall, was a white, southern slaveholder of humble origins, who spent time serving in the Confederate military. Beall, however, had also quickly established himself as one of the preeminent Democrats in his home county of Jefferson, as well as both the Shenandoah Valley and the new state of West Virginia. Beall firmly believed in the institution of racial slavery and fought to …


Lost-And-Found Photos: Practices And Perceptions, Todd J. Wemmer Mar 2016

Lost-And-Found Photos: Practices And Perceptions, Todd J. Wemmer

Doctoral Dissertations

Personal photographs become separated from their original owners in a number of ways, due to time or tragedy, sometimes ending up in strangers’ hands. Dealers, collectors, curators, bloggers, scholars, and families actively seek what are frequently called “orphaned,” “abandoned,” or “found” photos and present them to the public in multiple formats. This dissertation offers an analysis of the practices and perceptions that surround these presentations, and it argues for use of a more inclusive term (“lost-and-found”) to describe personal photos that are connected to both finders and losers. Data were collected in three primary ways: (1) examination of the current …


Change Of Sight, Sites Of Creativity: The Visual Arts In Albania After Socialism, Sofia Kalo Mar 2016

Change Of Sight, Sites Of Creativity: The Visual Arts In Albania After Socialism, Sofia Kalo

Doctoral Dissertations

This dissertation examines Albania’s fine art world after the end of state socialism in 1991. Drawing on two years of anthropological fieldwork (January –August 2006 and January 2010-August 2011) in Tirana, Albania’s capital city, this study investigates how the withdrawal of state support and oversight on the arts, the introduction of a market economy and efforts toward European belonging have been reflected, responded to and challenged in the discourses and practices of aesthetic production. Viewing art as a productive site of social meaning, where people perform and struggle over their identities, their pasts and futures, this dissertation explores the social …


A Step Of Two Or The Pas De Deux, Molly A. Hoisington Jul 2015

A Step Of Two Or The Pas De Deux, Molly A. Hoisington

Masters Theses

The second part of a two-part MFA Thesis presentation, this paper distills the content from the preceding exhibition A Step of Two or The Pas de Deux: an installation of paintings, drawings and projected video. It touches on various themes that surround [well researched] ideas about perception, dissociation, the gaze, and relationships. Most of all, this paper and the body of work it describes is about the visual representation of a sensual understanding of the world.


The Role Of Napping On Memory Consolidation In Preschool Children, Laura Kurdziel Nov 2014

The Role Of Napping On Memory Consolidation In Preschool Children, Laura Kurdziel

Doctoral Dissertations

Nocturnal sleep has been shown to benefit memory in adults and children. During the preschool age range (~3-5 years), the distribution of sleep across the 24-hour period changes dramatically. Children transition from biphasic sleep patterns (a nap in addition to overnight sleep) to a monophasic sleep pattern (only overnight sleep). In addition, early childhood is a time of neuronal plasticity and pronounced acquisition of new information. This dissertation sought to examine the relationship between daytime napping and memory consolidation in preschool-aged children during this transitional time. Children were taught either a declarative or an emotional task in the morning, and …


Age-Related Changes In Sleep-Dependent Consolidation Of Visuo-Spatial Memory, Akshata Sonni Nov 2014

Age-Related Changes In Sleep-Dependent Consolidation Of Visuo-Spatial Memory, Akshata Sonni

Masters Theses

Healthy aging is associated with a reduction in slow-wave sleep (SWS), crucial for declarative memory consolidation in young adults; consequently, previously observed benefits of sleep on declarative learning in older adults could reflect a passive role of sleep in protecting memories from waking interference, rather than an active, stabilizing effect. To dissociate the passive and active roles of sleep, a visuo-spatial task was administered; memory was probed after a 12 hr interval consisting of either daytime wake or overnight sleep and post-wake/post-sleep stability of the memories was tested following task-related interference. Ninety five older adults (mean=65.43 yrs; SD=7.6 yrs) and …


The Role Of Representational Flexibility In Toddlers' Manual Search, Lauren Hartstein Nov 2014

The Role Of Representational Flexibility In Toddlers' Manual Search, Lauren Hartstein

Masters Theses

In the model room task, children watch as a miniature toy is hidden somewhere in a scale model of a room and are asked to find the larger version of the toy in the corresponding place in the actual room. Previous work has shown that children under age three often perform very poorly on this task. One prominent theory for their failure is that they lack the ability to understand the model as both a physical object and as a symbolic representation of the larger room. An alternative hypothesis is that they need to overcome weak, competing representations of where …


Effects Of Aging On Sleep-Dependent Consolidation Of Declarative Memory, Bengi Baran Aug 2014

Effects Of Aging On Sleep-Dependent Consolidation Of Declarative Memory, Bengi Baran

Doctoral Dissertations

Sleep plays a critical role in memory consolidation. However, aging is associated with changes in sleep architecture and memory impairments. The goal of the present study was to identify age-related changes in the memory function of sleep by investigating sleep-dependent changes in neural activation patterns during memory retrieval in young and older adults. Healthy young (21-29 years) and older (62-74 years) adults were trained on a declarative word-pair learning task. Recall was tested 5 hr later while undergoing functional magnetic resonance imaging (fMRI). Participants completed this testing procedure twice, separated by 1 week; once following a mid-day nap and once …


The Genealogy Of Dislocated Memory: Yugoslav Cinema After The Break, Dijana Jelaca Apr 2014

The Genealogy Of Dislocated Memory: Yugoslav Cinema After The Break, Dijana Jelaca

Doctoral Dissertations

This dissertation analyzes the post-conflict cinema in the region of the former Yugoslavia, and the way that this particular form of cultural production establishes affective regimes within which bearing witness to trauma becomes variously articulated to national identity, history, politics, and memory. Using affect and trauma theories as organizing frameworks, my project looks at the way in which post-Yugoslav cinema has become a pivotal outlet for the process of working through the trauma of recent violent history in the region. I examine this process through its various iterations, from its applications to identity - be it ethnic, national, class, age, …


The Making Of Ras Beirut: A Landscape Of Memory For Narratives Of Exceptionalism, Maria B. Abunnasr Sep 2013

The Making Of Ras Beirut: A Landscape Of Memory For Narratives Of Exceptionalism, Maria B. Abunnasr

Open Access Dissertations

This dissertation examines the memory of Ras Beirut and the various claims to its exceptionalism. I frame its history as a landscape of memory born of the convergence of narratives of exceptionalism. On the one hand, Ras Beirut's landscape inspired Anglo-American missionary future providence such that they chose it as the site of their college on a hill, the Syrian Protestant College (SPC, later renamed the American University of Beirut [AUB]). On the other hand, the memory of Ras Beirut's "golden age" before the outbreak of the Lebanese Civil War in 1975 inspired longings for a vanished past to Ras …