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Ecologies, Synergies, And Biological Systems Shaping Human Milk Composition—A Report From “Breastmilk Ecology: Genesis Of Infant Nutrition (Begin)” Working Group 2, Jennifer T. Smilowitz, Lindsay H. Allen, David C. Dallas, James Mcmanaman, Daniel J. Raiten, Mary Rozga, David A. Sela, Antti Seppo, Janet E. Williams, Bridget E. Young, Michelle K. Mcguire
Ecologies, Synergies, And Biological Systems Shaping Human Milk Composition—A Report From “Breastmilk Ecology: Genesis Of Infant Nutrition (Begin)” Working Group 2, Jennifer T. Smilowitz, Lindsay H. Allen, David C. Dallas, James Mcmanaman, Daniel J. Raiten, Mary Rozga, David A. Sela, Antti Seppo, Janet E. Williams, Bridget E. Young, Michelle K. Mcguire
Food Science Department Faculty Publication Series
Human milk is universally recognized as the preferred food for infants during the first 6 mo of life because it provides not only essential and conditionally essential nutrients in necessary amounts but also other biologically active components that are instrumental in protecting, communicating important information to support, and promoting optimal development and growth in infants. Despite decades of research, however, the multifaceted impacts of human milk consumption on infant health are far from understood on a biological or physiological basis. Reasons for this lack of comprehensive knowledge of human milk functions are numerous, including the fact that milk components tend …
Cranberry Proanthocyanidins And Dietary Oligosaccharides Synergistically Modulate Lactobacillus Plantarum Physiology, Ezgi Özcan, Michelle Rozycki, David Sela
Cranberry Proanthocyanidins And Dietary Oligosaccharides Synergistically Modulate Lactobacillus Plantarum Physiology, Ezgi Özcan, Michelle Rozycki, David Sela
Food Science Department Faculty Publication Series
Plant-based foods contain bioactive compounds such as polyphenols that resist digestion and potentially benefit the host through interactions with their resident microbiota. Based on previous observations, we hypothesized that the probiotic Lactobacillus plantarum interacts with cranberry polyphenols and dietary oligosaccharides to synergistically impact its physiology. In this study, L. plantarum ATCC BAA-793 was grown on dietary oligosaccharides, including cranberry xyloglucans, fructooligosaccharides, and human milk oligosaccharides, in conjunction with proanthocyanidins (PACs) extracted from cranberries. As a result, L. plantarum exhibits a differential physiological response to cranberry PACs dependent on the carbohydrate source and polyphenol fraction introduced. Of the two PAC extracts …