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University of Connecticut

Theses/Dissertations

2016

Aging

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Examining Racial Differences Among Predictors Of Home And Community-Based Service Use And Choice And Control In Older Adults In The Money Follows The Person Program In Connecticut, Chanee Darnell Fabius May 2016

Examining Racial Differences Among Predictors Of Home And Community-Based Service Use And Choice And Control In Older Adults In The Money Follows The Person Program In Connecticut, Chanee Darnell Fabius

Doctoral Dissertations

The purpose of this study was to explore racial differences in home and community-based service (HCBS) use and perceived choice and control in frail elders ages 65 and older participating in the Money Follows the Person (MFP) demonstration program in Connecticut using the Andersen Behavioral Model of Health Service Utilization (1995). The comparison of Black and White program participants provides insight both for clinicians who work directly with frail elders and for researchers who seek to contribute to the gerontological field. This dissertation used secondary data collected from quality of life (QOL) interviews of (N=659) MFP participants who have transitioned …


Defining The Microglia Response To Ischemic Stroke Injury: The Role Of Cd200-Cd200r1 Signaling, Rodney M. Ritzel Jan 2016

Defining The Microglia Response To Ischemic Stroke Injury: The Role Of Cd200-Cd200r1 Signaling, Rodney M. Ritzel

Doctoral Dissertations

The work presented herein details our efforts at characterizing and understanding the mechanisms that govern microglia homeostasis and activation in the central nervous system (CNS). These studies have focused on the microglial response to aging and ischemic stroke, highlighting the importance of neuro-immune interactions and inflammatory signaling in the brain (Chapters 1 and 2). We begin with our investigations into microglial activity following ischemic brain injury and how these responses differ from that of other bone marrow-derived monocyte populations (Chapter 3). Then we define the role of the CD200-CD200R1 immuno-inhibitory signaling axis in ischemic stroke (Chapter 4), highlighting the importance …