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University of Central Florida

UCF Patents

2004

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Low Vapor Pressure, Low Debris Solid Target For Euv Production., Steven Fornaca, Roy Mcgregor, Mark Michaelian, Rocco Orsini, Michael Petach, Henry Shields Dec 2004

Low Vapor Pressure, Low Debris Solid Target For Euv Production., Steven Fornaca, Roy Mcgregor, Mark Michaelian, Rocco Orsini, Michael Petach, Henry Shields

UCF Patents

An EUV radiation source that creates a stable solid filament target. The source includes nozzle assembly having a condenser chamber for cryogenically cooling a gaseous target material into a liquid state. The liquid target material is filtered by a filter and sent to a holding chamber under pressure. The holding chamber allows entrained gas bubbles in the target being emitted from the nozzle assembly. The target material is forced through a nozzle outlet tube to be emitted from the nozzle assembly as a liquid target stream. A thermal shield is provided around the outlet tube to maintain the liquid target …


Pwm Half-Bridge Converter With Dual-Equally Adjustable Control Signal Dead-Time, Issa Batarseh, Jaber Abu Qahouq, Hong Mao Dec 2004

Pwm Half-Bridge Converter With Dual-Equally Adjustable Control Signal Dead-Time, Issa Batarseh, Jaber Abu Qahouq, Hong Mao

UCF Patents

A method and system of controlling half-bridge DC--DC converters to achieve Zero Voltage Switching (ZVS) for at least one of the switches. The soft-switching half-bridge DC--DC converter system includes soft-switching for all switches by adding an additional branch with a switch and a diode across the primary side of an isolation transformer and by applying a Duty-Cycle Shifted PWM Control.


Euv, Xuv, And X-Ray Wavelength Sources Created From Laser Plasma Produced From Liquid Metal Solutions, Martin Richardson Dec 2004

Euv, Xuv, And X-Ray Wavelength Sources Created From Laser Plasma Produced From Liquid Metal Solutions, Martin Richardson

UCF Patents

Metallic solutions at room temperature used a laser point source target droplets. Using the target metallic solutions results in damage free use to surrounding optical components since no debris are formed. The metallic solutions can produce plasma emissions in the X-rays, XUV, and EUV (extreme ultra violet) spectral ranges of approximately 11.7 nm and 13 nm. The metallic solutions can include molecular liquids or mixtures of elemental and molecular liquids, such as metallic chloride solutions, metallic bromide solutions, metallic sulphate solutions, metallic nitrate solutions, and organo-metallic solutions. The metallic solutions do not need to be heated since they are in …


Monolithic Silicon Euv Collector, Jonathan Arenberg, Frank Hassel Nov 2004

Monolithic Silicon Euv Collector, Jonathan Arenberg, Frank Hassel

UCF Patents

A collector optic assembly for a EUV radiation source. The collector optic assembly includes an elliptical meniscus having a reflective Si/Mo coating for collecting and reflecting EUV radiation generated by the source. The meniscus is machined from a single piece of silicon. The collector optic assembly further includes a heat exchanger that includes cooling channels through which flows a liquid coolant. The heat exchanger is fabricated from a plurality of machined silicon sections fused together by a glass frit bonding process. The meniscus is fused to a front side of the heat echanger by a glass frit bonding process. A …


Ac/Dc Switch Mode Power Supply With Power Factor Correction Using Direct Energy Transfer Concept, Issa Batarseh, Peter Kornetzky, Shiguo Luo, Weihong Qiu Nov 2004

Ac/Dc Switch Mode Power Supply With Power Factor Correction Using Direct Energy Transfer Concept, Issa Batarseh, Peter Kornetzky, Shiguo Luo, Weihong Qiu

UCF Patents

Power factor correction (PFC) "flyboost" cell with a transformer having primary winding connected to input power and secondary winding connected to output rectifier, which has both functions as a flyback transformer and boost inductor. Combining the flyboost cell with DC/DC converter cells, forms a single-stage PFC converters. Both cells share one main switch and one controller. Letting the flyboost cell operate at Discontinous Coduction Mode requires a simple control for high power factor. Through flyboost cell, part of output power is processed once by main switch, and is referred to as direct power transfer (DPT), which will signficantly improve efficiency. …


Free-Space Optical Communications With Partially Coherent Beams, Aristide Dogariu Oct 2004

Free-Space Optical Communications With Partially Coherent Beams, Aristide Dogariu

UCF Patents

This disclosure relates to a laser communication system for transmitting intelligence by means of partially coherent optical energy. The system provides improved transmission of intelligence from a transmitter site through non-confined free space and receiving said intelligence at a receiver site remote from and physically separate from said transmitter by non-confined free space. The system has a optical source at the transmitter site for producing a beam of spatially-coherent monochromatic, aperture limited electromagnetic optical energy as well as a modulator for modulating said beam with intelligence-bearing information to develop wavefronts of mutually-aligned orientation which beam is thereafter modified to partial …


Compact Lens Assembly For The Teleportal Augmented Reality System (Cip), Jannick Rolland, Yonggang Ha Oct 2004

Compact Lens Assembly For The Teleportal Augmented Reality System (Cip), Jannick Rolland, Yonggang Ha

UCF Patents

The projection lens system is designed for the head mounted projective display (HMPD) system to provide a wide field of view up to seventy degrees. The lens is optimized from a double-Gauss lens composed of two singlet lenses, one diffractive optical element (DOE) lens, one aspheric lens and a stop surface in the middle of the lens said lens has a focal length as low as approximately 23.9 mm whereby it has a field of view (FOV) of up to approximately 70 degrees and more. The lens can be combined with an additional field lens whereby the resulting lens combination …


Filtered Back Projection (Fbp) Algorithm For Computer Tomography [Div], Alexander Katsevich Oct 2004

Filtered Back Projection (Fbp) Algorithm For Computer Tomography [Div], Alexander Katsevich

UCF Patents

Reconstructing images of objects spirally scanned with two-dimensional detectors with a novel algorithm. The image reconstruction process is proven to create an exact image of the object under the ideal circumstances. The algorithm has an FBP (Filtered Back Projection) structure and works very efficiently. The algorithm uses less computer power and combines the benefits of Exact Algorithms and Approximate algorithms.


Cognitive Packet Network, Erol Gelenbe Oct 2004

Cognitive Packet Network, Erol Gelenbe

UCF Patents

A method of packet switching the packets in a data packet communication environment having a plurality of digital packet transmission stations interconnectable in paths. The steps include causing a first digital packet transmission of a smart data packet at a first end to send one or more smart data packets having a learning algorithm therein for learning a path to a second digital packet transmission station at a second end and then causing an acknowledgement packet to be sent from the second end having a learning path of the smart data packet from the first end to the second end …


Programmable Multiwavelength Modelocked Laser, Peter Delfyett, Trino Croeze, Eric Park, Hong Shi Oct 2004

Programmable Multiwavelength Modelocked Laser, Peter Delfyett, Trino Croeze, Eric Park, Hong Shi

UCF Patents

A programmable multiwavelength modelocked laser system. Embodiments of the system can use a computer, gratings, optical spectrum analyzer and SLM(spatial light modulator) inside of a laser cavity to control output amplitudes and phase of each of the wavelength channels of a multiple wavelength laser system. The programmable control allows for wavelength intensity(amplitude) levels of up to approximately 16 channels to be controlled and evened out. An InGaAsP SOA based modelocked multiwavelength ring laser is stabilized using a programmable liquid crystal spatial light modulator in a feedback control loop. The system produces 16 independent modelocked RZ wavelength channels at 10 GHz …


Single Cell Gap Transflective Liquid Crystal Display With Slanted Reflector Above Transmissive Pixels, Shin-Tson Wu, Yi-Pai Huang, Han-Ping Shieh, Y Zhu Oct 2004

Single Cell Gap Transflective Liquid Crystal Display With Slanted Reflector Above Transmissive Pixels, Shin-Tson Wu, Yi-Pai Huang, Han-Ping Shieh, Y Zhu

UCF Patents

Single cell gap transflective liquid crystal display which provides that the backlight traverses the reflective pixel portion twice and thereby follows a path similar to that of the ambient light. A slant reflector is built on the path of the back light to reflect the transmitted light to the reflective portion so that the back light and ambient light follow similar paths.


Target Steering System For Euv Droplet Generators, Steven Fornaca, Rocco Orsini, Michael Petach Sep 2004

Target Steering System For Euv Droplet Generators, Steven Fornaca, Rocco Orsini, Michael Petach

UCF Patents

No abstract provided.


Narrow Band Transmitting-Receiving Telescope System, Oleg Efimov Aug 2004

Narrow Band Transmitting-Receiving Telescope System, Oleg Efimov

UCF Patents

This disclosure relates to a laser communication system which allows changing the direction of reception and transmission without external manipulation of the system container. The basic unit of the system is a narrow-band transmitting-receiving telescope apparatus which includes a rotating diffraction grating and an independently rotating stage with mounted combination of photodetector for reception and laser for transmission and a focusing system concentrating the beam reflected from the grating onto the photodetector of the combination or sending a beam from laser of the combination onto the grating. The selection of definite angles for signal transmission-reception is realized by corresponding rotation …


Teleportal Face-To-Face System., Jannick Rolland, Ceyhun Akcay, Frank Biocca, Henley Quadling, Mark Quadling, Haocheng Zheng Aug 2004

Teleportal Face-To-Face System., Jannick Rolland, Ceyhun Akcay, Frank Biocca, Henley Quadling, Mark Quadling, Haocheng Zheng

UCF Patents

A teleportal system which provides remote communication between at least two users. A projective display and video capture system provides video images to the users. The video system obtains and transmits 3D images which are stereoscopic to remote users. The projective display unit provides an augmented reality environment to each user and allows users to view, unobstructed, the other local users, and view a local site in which they are located. A screen transmits to the user the images generated by the projective display via a retro-reflective fabric upon which images are projected and reflected back to the users eyes.


Method Of Reconstructing Images For Spiral And Non-Spiral Computer Tomography, Alexander Katsevich Aug 2004

Method Of Reconstructing Images For Spiral And Non-Spiral Computer Tomography, Alexander Katsevich

UCF Patents

General scheme processes and systems for constructing algorithms for reconstructing images of objects that have been scanned in a spiral or non-spiral fashions with detectors. Application of the scheme requires finding of a weight function, which would lead to the required reconstruction algorithm. This general scheme can use a C-arm scan with the closed x-ray source trajectory and gives a new, theoretically exact and efficient (i.e., with the convolution-based FBP structure) reconstruction algorithm. The invention can also utilize the algorithms disclosed in an earlier application U.S. application Ser. No. 10/143,160 filed May 10, 2002, entitled: Exact Filtered Back Projection (FBP) …


Electrochemical Deposition Of Carbon Nanotubes From Organic Solutions, Lee Chow, Elvira Anoshkina, Dan Zhou Jul 2004

Electrochemical Deposition Of Carbon Nanotubes From Organic Solutions, Lee Chow, Elvira Anoshkina, Dan Zhou

UCF Patents

Carbon nanoparticles including both nanofilaments and nanotubes produced by an electrochemical deposition method from organic solutions at room temperature, in which the formation and growth of carbon nanoparticles are stimulated by the catalyst, such as iron and nickel. It has been found that the electrochemical deposition conditions have a strong influence on the growth phenomenon of the carbon nanotubes. Scanning electron microscope (SEM) and transmitting electron microscope (TEM) characterizations show that the diameter of nanotubes is of the order of approximately 100 nm, and the length of filaments can be up to approximately 50 .mu.m, depending on the size of …


Linear Filament Array Sheet For Euv Production., Rocco Orsini, Michael Petach Jun 2004

Linear Filament Array Sheet For Euv Production., Rocco Orsini, Michael Petach

UCF Patents

An EUV radiation source that generates a sheet of a liquid target material that has a width that matches the desired laser spot size for good conversion efficiency and a thickness that matches the laser beam/target interaction depth. The EUV source includes a reservoir containing a pressurized cryogenic liquid target material. such as liquid Xenon. The reservoir also includes an array of closely spaced orifices into a vacuum chamber as separated liquid stream filaments of the target material that define the sheet. The liquid streams freeze to form an array of frozen target filaments. A laser beam is directed to …


Wheelchair Table With Ergonomic Aid, Robert Hoekstra, Jose Gonzalez, Jon Moen, Michael Mullens, Rashendra Shah, Prasanth Thupili May 2004

Wheelchair Table With Ergonomic Aid, Robert Hoekstra, Jose Gonzalez, Jon Moen, Michael Mullens, Rashendra Shah, Prasanth Thupili

UCF Patents

An attachable and detachable wheelchair tray with an adjustable work surface is disclosed. The adjustable work surface has two parts connected with a hinge. Part one is a horizontal stationary supporting base and part two is a movable top portion which can be tilted in an angular range of from 90 degrees to 180 degrees in relationship to the horizontal base. There is also an extendible auxiliary supporting rack attached to the movable top portion that allows the user to enlarge or reduce the work surface, thus permitting access to more items, references publications at a time. All adjustments of …


Non Invasive Method And Low Coherence Apparatus For System Analysis, Aristide Dogariu May 2004

Non Invasive Method And Low Coherence Apparatus For System Analysis, Aristide Dogariu

UCF Patents

The disclosure relates to measuring devices that are particularly suited for the purpose of in-situ characterization of particles present in fluid substances or in air using a low-coherence interferometer. Specifically, the characterization includes average size, size distribution, volumetric density, and composition. The low-coherence interferometer utilizes a split band of radiation to illuminate a sample probe and a reference probe then combines the reflected radiation from both probes to determine the photon pathlength distribution of the tested particulate or colloidal containing stream and from this information determine the size characteristics of said stream. The methodology is relevant to possible spatially distributed …


Gasdynamically-Controlled Droplets As The Target In A Laser-Plasma Extreme Ultraviolet Light Source, Roy Mcgregor, Robert Bunnell, Michael Petach, Rocco Orsini May 2004

Gasdynamically-Controlled Droplets As The Target In A Laser-Plasma Extreme Ultraviolet Light Source, Roy Mcgregor, Robert Bunnell, Michael Petach, Rocco Orsini

UCF Patents

A target material delivery system in the form of a nozzle for an EUV radiation source. The nozzle includes a target material supply line having an orifice through which droplets of a liquid target material are emitted, where the droplets have a predetermined size, speed and spacing therebetween. The droplets are mixed with a carrier gas in a mixing chamber enclosing the target material chamber and the mixture of the droplets and the carrier gas enter a drift tube from the mixing chamber. The droplets are emitted into an accelerator chamber from the drift tube where the speed of the …


Apparatus And Method For Drawing Continuous Fiber, Aravinda Kar, Yonggang Li, Raymond Mcneice, Nathaniel Quick May 2004

Apparatus And Method For Drawing Continuous Fiber, Aravinda Kar, Yonggang Li, Raymond Mcneice, Nathaniel Quick

UCF Patents

An apparatus and method is disclosed for drawing continuous metallic wire having a first diameter to a metallic fiber having a reduced second diameter. A feed mechanism moves the wire at a first linear velocity. A laser beam heats a region of the wire to an elevated temperature. A draw mechanism draws the heated wire at a second and greater linear velocity for providing a drawn metallic fiber having the reduced second diameter.


Ultralow Noise Optical Clock For High Speed Sampling Aplications, Peter Delfyett, Depriest Christopher, Tolga Yilmaz May 2004

Ultralow Noise Optical Clock For High Speed Sampling Aplications, Peter Delfyett, Depriest Christopher, Tolga Yilmaz

UCF Patents

Methods and systems for using a laser type clock to produce a train of ultra-stable optical pulses. The methods and systems include generating an approximately 10 GHz ultralow noise pulse train from a harmonically modelocked laser having an intracavity Fabry-Perot etalon filter from a semiconductor lasers such as ring lasers, and the like. System output can have residual phase modulation(PM) noise values of approximately 18 fs and amplitude modulation(AM) noise values of approximately 0.05% RMS, and residual phase modulation(PM) noise values of approximately 94 fs and amplitude modulation(AM) noise values of approximately 0.05% RMS.


Compact Lens Assembly For The Teleportal Augmented Reality System, Jannick Rolland, Hong Hua May 2004

Compact Lens Assembly For The Teleportal Augmented Reality System, Jannick Rolland, Hong Hua

UCF Patents

A compact, ultra-light and high-performance projection optics lens assembly using Diffractive Optics Technology, plastic and glass optics, and Aspheric optics has been designed with only four elements. The lens may be included as is, or scaled to be included in all instruments using conventional Double-Gauss lens forms. The preferred lens is only 20 mm in diameter and 15 mm long has a weight of only 8 g. Thus, two lenses for head mounted stereo displays is only 16 g. Such a stereo display, known as a head-mounted projective display (HMPD), consists of a pair of miniature projection lenses, beam splitters, …


Treatment Of Breast Cancer, Delbert Miles, Elena Goun, Elena Goun, Krasnych Pertrovna, Krasnych Pertrovna, Pimenova Valentinovna, Solodnikov Yurjevich, Solodnikov Yyrjevitsh Mar 2004

Treatment Of Breast Cancer, Delbert Miles, Elena Goun, Elena Goun, Krasnych Pertrovna, Krasnych Pertrovna, Pimenova Valentinovna, Solodnikov Yurjevich, Solodnikov Yyrjevitsh

UCF Patents

Compounds of the class of 4-oxo-butenoic acid derivatives are disclosed along with the surprising use property of these compounds as a anti-tumor agents in humans against breast carcinoma, which include: 2-(N'-Fluoren-9-ylidene-hydrazino)-5,5-dimethyl-4-oxo-hex-2-enoic acid methyl ester (OF-06), 1-(2,4-Dimethyl-phenyl)-2,4-dihydroxy-3-4-methyl-benzoyl)-5-oxo-2,5-dihydro-1H-pyrrole-2-carboxylic acid methyl ester (1F-07), 4-(4-Methoxy-phenyl)-2,4-dioxo-3-(phenyl-hydrazono)-butyric acid (3F-10), 4-(4-Chloro-phenyl)-2,4-dioxo-3-(phenyl-hydrazono)-butyric acid ethyl ester (3F-11), 2-Hydroxy-4-oxo-4-(2,3,5,6-tetrafluoro-4-methoxy-phenyl)-but-2-enoic acid (3F-15), and 4,4-Dihydroxy-5-4-methyl-benzoyl)-2-phenyl-2,4-dihydro-pyrazol-3-one (3F-16) as well as some novel derivatives of these compounds claimed (see Table 2). The invention also encompasses a class of the compounds with the novel property of anti-tumor activity against human breast cancer, which includes the following compounds 4-(4-Ethoxy-phenyl)-2-(N'-fluoren-9-ylidene-hydrazino)-2-hydroxy-4-oxo-butyric acid methyl ester (OF-13); 2-{N'-[1-(4-Chloro-phenyl)-ethylidene]-hydrazino}-4-oxo-4-phenyl-but-2-enoic acid methyl …


Automatic Motion Modeling Of Rigid Bodies Using Collision Detection, Jannick Rolland, Yoahan Baillot Mar 2004

Automatic Motion Modeling Of Rigid Bodies Using Collision Detection, Jannick Rolland, Yoahan Baillot

UCF Patents

An algorithim for modeling the interaction of two colliding rigid objects. The algorithm allows the search of the optimal position and stabilization of two rigid objects when they are in contact due to a force pushing them against each other. The method does use mathematical integration and does not use any initial acceleration or speed conditioning for the results. The pushing direction can be changed at any time of the search for a correct specification. The moving solid is translated and rotated incrementally toward the equilibrium position and orientation in a non-natural way but leading to the same final attitude …


Method Of Identifying And Treating Invasive Carcinomas (Div.B), Xinqing Chai, Julie Chao, Lee Chao, Limei Chen Mar 2004

Method Of Identifying And Treating Invasive Carcinomas (Div.B), Xinqing Chai, Julie Chao, Lee Chao, Limei Chen

UCF Patents

Prostasin protein has been found to be a useful marker for determination of the invasiveness of and as a means to treat human carcinomas. Using RT-PCR and western blot analyses, prostasin protein and mRNA expression were found in normal human prostate epithelial cells and the human prostate cancer cell line LNCaP, but not in the highly invasive human prostate cancer cell lines DU-145 and PC-3. Imunohistochemistry studies of human prostate cancer specimens revealed a down-regulation of prostasin in high-grade tumors. Using RT-PCR and western blot analyses, prostasin protein and mRNA expression were found in a non-invasive human breast cancer cell …


Treatment Of Breast Cancer, Delbert Miles, Elena Goun, Krasnych Pertrovna, Pimenova Valentinovna, Solodnikov Yurjevich Mar 2004

Treatment Of Breast Cancer, Delbert Miles, Elena Goun, Krasnych Pertrovna, Pimenova Valentinovna, Solodnikov Yurjevich

UCF Patents

Compounds of the class of 4-oxo-butenoic acid derivatives are disclosed along with the surprising use property of these compounds as a anti-tumor agents in humans against breast carcinoma, which include: 2-(N'-Fluoren-9-ylidene-hydrazino)5,5-dimethyl-4-oxo-hex-2-enoic acid methyl ester (OF-06), 1-(2,4-Dimethyl-phenyl)-2,4-dihydroxy-3-(4-methyl-benzoyl)-5-oxo-2,5-dihydro-1H-pyrrole-2-carboxylic acid methyl ester (1F-07), 4-(4-Methoxy-phenyl)-2,4-dioxo-3-(phenyl-hydrazono)-butyric acid (3F-10), 4-(4-Chloro-phenyl)-2,4-dioxo-3-(phenyl-hydrazono)-butyric acid ethyl ester (3F-11), 2-Hydroxy-4-oxo-4-(2,3,5,6-tetrafluoro-4-methoxy-phenyl)-but-2-enoic acid (3F-15), and 4,4-Dihydroxy-5-(4-methyl-benzoyl)-2-phenyl-2,4-dihydro-pyrazol-3-one (3F-16) as well as some novel derivatives of these compounds claimed (see Table 2). The invention also encompasses a class of the compounds with the novel property of anti-tumor activity against human breast cancer, which includes the following compounds 4-(4-Ethoxy-phenyl)-2-(N'-fluoren-9-ylidene-hydrazino)-2-hydroxy-4-oxo-butyric acid methyl ester (OF-13); 2-{N'-[1-(4-Chloro-phenyl)-ethylidene]-hydrazino}-4-oxo-4-phenyl-but-2-enoic acid methyl …


Method Of Identifying And Treating Invasive Carcinomas (Div.A), Xinqing Chai, Julie Chao, Lee Chao, Limei Chen Feb 2004

Method Of Identifying And Treating Invasive Carcinomas (Div.A), Xinqing Chai, Julie Chao, Lee Chao, Limei Chen

UCF Patents

Prostasin protein has been found to be a useful marker for determination of the invasiveness of and as a means to treat human carcinomas. Using RT-PCR and western blot analyses, prostasin protein and mRNA expression were found in normal human prostate epithelial cells and the human prostate cancer cell line LNCaP, but not in the highly invasive human prostate cancer cell lines DU-145 and PC-3. Imunohistochemistry studies of human prostate cancer specimens revealed a down-regulation of prostasin in high-grade tumors. Using RT-PCR and western blot analyses, prostasin protein and mRNA expression were found in a non-invasive human breast cancer cell …


Method Of Reducing Amplitude Noise In Multiwavelength Modelocked Semiconductor Lasers, Peter Delfyett, Michael Mielke Feb 2004

Method Of Reducing Amplitude Noise In Multiwavelength Modelocked Semiconductor Lasers, Peter Delfyett, Michael Mielke

UCF Patents

Multiwavelength modelocked laser systems and methods for reducing intensity fluctuations and amplitude noise in each of the wavelength channels as well as manipulating the interwavelength phase coherence properties. The systems and methods can include lens, semiconductor optical amplifier, grating, cylindrical lens, rod lens and an approximately 7 nm MQW saturable absorber between mirrors for providing a laser cavity resonator for hybridly modelocked operation. Additional systems and methods can include two different positions for the saturable absorber inside the laser resonator which enables direction of the interwavelength phase coherence properties. Up to approximately 300 MHz optical pulse trains in each of …


Treatment Of Myeloma, Delbert Miles, Elena Goun, Natalia Konuchova, Tatiana Koretkova, Krasnych Pertrovna, Pimenova Valentinovna, Solodnikov Yurjevich, Solodnikov Yyrjevitsh Feb 2004

Treatment Of Myeloma, Delbert Miles, Elena Goun, Natalia Konuchova, Tatiana Koretkova, Krasnych Pertrovna, Pimenova Valentinovna, Solodnikov Yurjevich, Solodnikov Yyrjevitsh

UCF Patents

This patent is filed in order to new 4 oxo 2 butenoic acid heterocyclic that are synthesised according to schemes 1 and 2. More specifically this patent is for compounds OF-06 OF-13 1F-07 3F-11 and 3F-16 which are shown in table 1. All of these compounds are novel have high eactivity against colon and breast cancer and low toxicity in animals.