Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 3 of 3
Full-Text Articles in Entire DC Network
Swept-Source Based, Single-Shot, Multi-Detectable Velocity Range Doppler Optical Coherence Tomography, Panomsak Meemon, Jannick P. Rolland
Swept-Source Based, Single-Shot, Multi-Detectable Velocity Range Doppler Optical Coherence Tomography, Panomsak Meemon, Jannick P. Rolland
Faculty Bibliography 2010s
Phase-Resolved Doppler Optical Coherence Tomography (PR-DOCT) allows visualization and characterization of the location, direction, velocity, and profile of flow activity embedded in a static sample structure. The detectable Velocity Dynamic Range (VDR) of each particular PR-DOCT system is governed by a detectable Doppler phase shift, a flow angle, and an acquisition time interval used to determine the Doppler phase shift. In general, the lower boundary of the detectable Doppler phase shift is limited by the phase stability of the system, while the upper boundary is limited by the pi phase ambiguity. For a given range of detectable Doppler phase shift, …
Doppler Imaging With Dual-Detection Full-Range Frequency Domain Optical Coherence Tomography, Panomsak Meemon, Kye-Sung Lee, Jannick P. Rolland
Doppler Imaging With Dual-Detection Full-Range Frequency Domain Optical Coherence Tomography, Panomsak Meemon, Kye-Sung Lee, Jannick P. Rolland
Faculty Bibliography 2010s
Most of full-range techniques for Frequency Domain Optical Coherence Tomography (FD-OCT) reported to date utilize the phase relation between consecutive axial lines to reconstruct a complex interference signal and hence may exhibit degradation in either mirror image suppression performance or detectable velocity dynamic range or both when monitoring a moving sample such as flow activity. We have previously reported a technique of mirror image removal by simultaneous detection of the quadrature components of a complex spectral interference called a Dual-Detection Frequency Domain OCT (DD-FD-OCT) [Opt. Lett. 35, 1058-1060 (2010)]. The technique enables full range imaging without any loss of acquisition …
Folate Receptor Targeting Silica Nanoparticle Probe For Two-Photon Fluorescence Bioimaging, Xuhua Wang, Sheng Yao, Hyo-Yang Ahn, Yuanwei Zhang, Mykhailo V. Bondar, Joseph A. Torres, Kevin D. Belfield
Folate Receptor Targeting Silica Nanoparticle Probe For Two-Photon Fluorescence Bioimaging, Xuhua Wang, Sheng Yao, Hyo-Yang Ahn, Yuanwei Zhang, Mykhailo V. Bondar, Joseph A. Torres, Kevin D. Belfield
Faculty Bibliography 2010s
Narrow dispersity organically modified silica nanoparticles (SiNPs), diameter similar to 30 nm, entrapping a hydrophobic two-photon absorbing fluorenyl dye, were synthesized by hydrolysis of triethoxyvinylsilane and (3-aminopropyl) triethoxysilane in the nonpolar core of Aerosol-OT micelles. The surface of the SiNPs were functionalized with folic acid, to specifically deliver the probe to folate receptor (FR) over-expressing Hela cells, making these folate two-photon dye-doped SiNPs potential candidates as probes for two-photon fluorescence microscopy (2PFM) bioimaging. In vitro studies using FR over-expressing Hela cells and low FR expressing MG63 cells demonstrated specific cellular uptake of the functionalized nanoparticles. One-photon fluorescence microscopy (1PFM) imaging, …