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Vagal Mediated Heart Rate Variability And Cognitive Impairments In Hiv-Seropositive Women, William C. Nicholson
Vagal Mediated Heart Rate Variability And Cognitive Impairments In Hiv-Seropositive Women, William C. Nicholson
All ETDs from UAB
Regardless of sufficient viral suppression, HIV exerts an ongoing inflammatory process that promotes chronic autonomic nervous system (ANS) dysfunction, accelerates physiological aging, and increases the risk of developing a spectrum of cognitive disorders (known as HIV-associated neurocognitive disorders [HAND]). Given this, identifying pathological mediators of this inflammatory response could provide insight into the mechanisms driving HAND. The vagus nerve (indexed by vagal-mediated heart rate variability [vmHRV]) could provide such a mediator as it regulates ANS activity via reciprocal cardio-neural pathways, which regulate inflammation and homeostasis. Vagal dysfunction is associated with persistent inflammatory signaling (e.g., stress or inflammatory-based disorders [such as …
Hpv And Hsv Associated Clinical Conditions Among People Living With Hiv-1 Infection, Yuanfan Ye
Hpv And Hsv Associated Clinical Conditions Among People Living With Hiv-1 Infection, Yuanfan Ye
All ETDs from UAB
This dissertation research focuses on investigating health burdens of HPV- and HSV- associated clinical conditions (CC) in people living with HIV-1 infection (PLWH) in the Southeastern United States. I designed a retrospective study using the UAB 1917 HIV Clinic Cohort. Electronic health records of PLWH attending the clinic for HIV-care between January 2006 and March 2019 were obtained and reviewed. I first examined incidence rates and trends of anogenital HPV- and HSV-associated CC. Then I adopted a new algorithm to group longitudinal CD4 cell counts based on their trajectories. I compared it with nadir and median CD4 cell counts in …
Sexual Health Risk And Hiv Prevention: An Exploratory Study Of Behavior Among Heterosexual, African American Men And Women In Birmingham, Alabama., Kiko J. King
All ETDs from UAB
ABSTRACT The Deep South of the U.S. continues to have increased incidence of new cases of HIV since its inception, despite many advancements in HIV testing, treatment, and prevention. According to data by the CDC, rates are increasingly high among heterosexual African American (AA) men and women compared to their non-AA counterparts (CDC/HIV, 2017). In 2015, heterosexual transmission accounted for a share of new diagnoses for AA men and is the most common transmission route for AA women (KFF, 2017). The primary population affected by HIV/AIDS in Alabama is men who have sex with men (MSM) at 62.2%, followed by …
Occupational Health Outcomes In Women Living With And At Risk For Hiv, Jenni Wise
Occupational Health Outcomes In Women Living With And At Risk For Hiv, Jenni Wise
All ETDs from UAB
Women living with HIV (WLWH) are now able to work and need to work to attain the fruitful benefits of employment. Regardless of the need for income, employment provides esteem, confidence, structure, social support, and is associated with improved physical and psychological outcomes. Yet, in spite of the documented benefits associated with employment, an estimated 60% of WLWH are not employed. Thus, occupational disparities among WLWH contribute to disparities in health and quality of life among this population. While the historical trajectory of HIV is unique compared to other populations with chronic disease, evidence suggests that gender-specific difference in socioeconomic, …