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The Relationship Of Bedside Assessment Of Orientation And Cognition To Treatment Outcome In Moderate To Severe Traumatic Brain Injury: A Growth Curve Analysis, Amber Marie Fahey
The Relationship Of Bedside Assessment Of Orientation And Cognition To Treatment Outcome In Moderate To Severe Traumatic Brain Injury: A Growth Curve Analysis, Amber Marie Fahey
All ETDs from UAB
Disorientation and cognitive impairment are commonly experienced in acute moderate to severe TBI patients and deficits early in recovery are predictive of worse long-term outcome. Hence, tracking recovery over time is a significant aspect of rehabilitation research. The Orientation-Log (O-log) and Cognition-Log (Cog-log) are important clinical measures used to monitor cognitive progress during treatment and previous research has shown them to be predictive of long-term outcome. This study used two-level growth curve modeling to, 1) determine the growth trajectory of orientation and cognition in persons with moderate to severe TBI in acute rehabilitation, as determined by the O-log and Cog-log, …
The Relationship Between Cortical Excitability And Neuropsychological Functioning In Patients With Idiopathic Generalized Epilepsies (Iges), Lauren Bolden
All ETDs from UAB
Recent advances in neurostimulation and neuromodulation techniques, such as transcranial magnetic stimulation (TMS), may offer alternative treatment options to patients with idiopathic generalized epilepsies (IGEs). In a previous study, we utilized TMS to demonstrate a relationship between increased cortical excitability (i.e. hyperexcitability), attentional dysfunction, and mood disturbance in a sample of healthy adults. In general, patients with IGEs are found to exhibit cortical hyperexcitability, cognitive dysfunction, and mood problems; however, a relationship between these variables in IGEs has not yet been investigated. Importantly, patients with treatment-resistant IGEs (trIGEs) are shown to demonstrate greater cortical excitability, cognitive deficits, and mood problems …
Neurocognition In Patients With Primary Dystonia, Lindsay Niccolai
Neurocognition In Patients With Primary Dystonia, Lindsay Niccolai
All ETDs from UAB
Dystonia is defined as involuntary, sustained muscle contractions often causing twisting and repetitive movements. While dystonia is classified as a movement disorder with marked motor disturbance, there are also non-motor features associated with this disorder such as psychiatric, sensory, and neurocognitive deficits. This dissertation research focuses on the neurocognitive deficits found in patients with primary dystonia. Prior studies examining cognition in primary dystonia have often had the limitations of having small samples and lacking control groups. In addition, cognition is often assessed in deep brain stimulation (DBS) surgical candidacy evaluations, but neurocognitive deficits have not been studied as a predictor …