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Genetic Contributions To The Midsagittal Area Of The Corpus Callosum, Kimberley A. Phillips, J. Rogers, E. A. Barrett, D. C. Glahn, P. Kochunov
Genetic Contributions To The Midsagittal Area Of The Corpus Callosum, Kimberley A. Phillips, J. Rogers, E. A. Barrett, D. C. Glahn, P. Kochunov
Psychology Faculty Research
The degree to which genes and environment determine variations in brain structure and function is fundamentally important to understanding normal and disease-related patterns of neural organization and activity. We studied genetic contributions to the midsagittal area of the corpus callosum (CC) in pedigreed baboons (68 males, 112 females) to replicate findings of high genetic contribution to that area of the CC reported in humans, and to determine if the heritability of the CC midsagittal area in adults was modulated by fetal development rate. Measurements of callosal area were obtained from high-resolution MRI scans. Heritability was estimated from pedigree-based maximum likelihood …