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A Randomized Controlled Dosing Study Of Iyengar Yoga And Coherent Breathing For The Treatment Of Major Depressive Disorder: Impact On Suicidal Ideation And Safety Findings, Maren Nyer, Patricia Gerbarg, Marisa M. Silveri, Jennifer Johnston, Tammy M. Scott, Maya Nauphal, Liz Owen, Greylin H. Nielsen, David Mischoulon, Richard P. Brown, Maurizio Fava, Chris C. Streeter Apr 2018

A Randomized Controlled Dosing Study Of Iyengar Yoga And Coherent Breathing For The Treatment Of Major Depressive Disorder: Impact On Suicidal Ideation And Safety Findings, Maren Nyer, Patricia Gerbarg, Marisa M. Silveri, Jennifer Johnston, Tammy M. Scott, Maya Nauphal, Liz Owen, Greylin H. Nielsen, David Mischoulon, Richard P. Brown, Maurizio Fava, Chris C. Streeter

NYMC Faculty Publications

BACKGROUND: Yoga interventions offer promise for the treatment of major depressive disorder (MDD), yet their safety and potential impact on suicidal ideation (SI) have not been well documented. This study evaluated the safety of a randomized controlled dose-finding trial of Iyengar yoga plus coherent breathing for individuals with MDD, as well as the potential effects of the intervention on SI without intent. METHODS: Participants with Beck Depression Inventory-II (BDI-II) scores >/=14 and a diagnosis of MDD (using DSM-IV criteria) were randomized to either a low dose group (LDG) or high dose group (HDG) and received a 12-week manualized intervention. The …


Exposure To Gender-Based Violence And Depressive Symptoms Among Transgender Women In Cambodia: Findings From The National Integrated Biological And Behavioral Survey 2016, Siyan Yi, Sovannary Tuot, Srean Chhim, Pheak Chhoun, Phalkun Mun, Gitau Mburu Jan 2018

Exposure To Gender-Based Violence And Depressive Symptoms Among Transgender Women In Cambodia: Findings From The National Integrated Biological And Behavioral Survey 2016, Siyan Yi, Sovannary Tuot, Srean Chhim, Pheak Chhoun, Phalkun Mun, Gitau Mburu


Background: Transgender women are at significant risk of HIV, and they face intersecting barriers to health, social, and legal services. However, data regarding the unique needs and experiences of transgender women are globally scant. This study examined the relationship between gender-based violence and depressive symptoms among transgender women in Cambodia.

Methods: This cross-sectional study included 1375 sexually active transgender women recruited by using the respondent-driven sampling method in the capital city of Phnom Penh and 12 provinces between December 2015 and February 2016. Depressive symptoms were assessed using the Center for Epidemiologic Studies Depression scale (CES-D). Multivariate regression analysis was …


Effects Of Yoga On Thalamic Gamma-Aminobutyric Acid, Mood And Depression: Analysis Of Two Randomized Controlled Trials, Chris C. Streeter, Patricia L. Gerbarg, Greylin H. Nielsen, Richard P. Brown, J Eric Jensen, Marisa M. Silveri Jan 2018

Effects Of Yoga On Thalamic Gamma-Aminobutyric Acid, Mood And Depression: Analysis Of Two Randomized Controlled Trials, Chris C. Streeter, Patricia L. Gerbarg, Greylin H. Nielsen, Richard P. Brown, J Eric Jensen, Marisa M. Silveri

NYMC Faculty Publications

Objective: The Vagal-Gamma-Aminobutyric Acid (GABA) theory proposes that some yoga postures and breathing practices exert their effects through stimulation of vagal nerves (parasympathetic system) with associated brain GABA increases. To evaluate this theory, we compared results from a 12-week randomized controlled trial (RCT) of yoga in participants with Major Depressive Disorder (MDD) with those of a similar RCT in healthy control participants (HC).

Methods: In an RCT, magnetic resonance spectroscopy (MRS) and mood measures were acquired in subjects with MDD (n=15) prior to and following a 12-week yoga intervention. The same measures were obtained in the HC (n=17) group. In …