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Haploidentical Hematopoietic Stem Cell Transplantation: Rationale, Development, And Jefferson’S Method, Susan Mcilvaine, Dolores Grosso, Rn, Crnp, Dnp, Beth Colombe Jun 2014

Haploidentical Hematopoietic Stem Cell Transplantation: Rationale, Development, And Jefferson’S Method, Susan Mcilvaine, Dolores Grosso, Rn, Crnp, Dnp, Beth Colombe

Department of Pathology Honors Program Student Research Symposium

INTRODUCTION

There are many indications for hematopoietic stem cell transplantation. In addition to hematologic malignancies, transplants are performed in certain non-hematologic malignancies, for marrow disorders such as Sickle Cell Anemia, and for various inherited disorders such as SCID. Traditionally, transplants have been performed between donors and recipients that are a complete HLA match (typically matched siblings). That is, patients have identical HLA alleles on both copies of chromosome 6. HLA alleles code for major histocompatibility complex molecules, which are the proteins that cause transplant rejection when a mismatch between donor and recipient is present. Thus, matched transplants have been historically …


Counseling Women And Men Regarding Exposures To Reproductive And Developmental Toxicants Before Conception Or Women During Pregnancy: Determining Whether The Exposure Has Increased Their Reproductive Or Developmental Risks, Robert L. Brent Dr. Jan 2014

Counseling Women And Men Regarding Exposures To Reproductive And Developmental Toxicants Before Conception Or Women During Pregnancy: Determining Whether The Exposure Has Increased Their Reproductive Or Developmental Risks, Robert L. Brent Dr.

The Selected Works of Robert Brent

No abstract provided.