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Articles 1 - 5 of 5
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Phylogenetic Analysis Of Human Cytomegalovirus Pus27 And Pus28: Ascertaining An Independent Or Linked Evolutionary History, Jessica A. Scarborough
Phylogenetic Analysis Of Human Cytomegalovirus Pus27 And Pus28: Ascertaining An Independent Or Linked Evolutionary History, Jessica A. Scarborough
Undergraduate Honors Theses
Human cytomegalovirus (HCMV) is a widespread pathogen that is particularly skilled at evading immune detection and defense mechanisms, largely due to extensive co-evolution with its host’s immune system. One aspect of this co-evolution involves the acquisition of four virally encoded GPCR chemokine receptor homologs, products of the US27, US28, UL33 and UL78 genes. G protein-coupled receptors (GPCR) are the largest family of cell surface proteins, found in organisms from yeast to humans. In this research, phylogenetic analysis was used to investigate the origins of the US27 and US28 genes, which are adjacent in the viral genome. The results indicate that …
De-Westernizing The Far East, Jericho K. Kakaio-Edwards
De-Westernizing The Far East, Jericho K. Kakaio-Edwards
Undergraduate Honors Theses
Isolated by the Tibetan highlands which frame Yunnan’s northwest fringes, the ethnic minorities who call the region home live in rural settings ranging from rice-terraced fields to tropical forests; lifestyle unchanged for hundreds of years. However, with globalization causing an exposure to western standards of living, in conjunction with the country’s predisposition towards all things foreign, the people of Yunnan have begun forgoing generations of vernacular architecture in favor of modern materials and regionally defunct construction methods. Here, we will seek to address this foible of architectural development by offering theoretical construction methods for housing types found throughout the region, …
From Empty Lot To Garden Plot: Urban Agriculture In Chula Vista, Jennifer E. Gutierrez
From Empty Lot To Garden Plot: Urban Agriculture In Chula Vista, Jennifer E. Gutierrez
Undergraduate Honors Theses
This project is an exploration of how agriculture can be incorporated into the fabric of the city of Chula Vista, which has both uniquely urban and suburban areas. The proposal is to integrate agriculture as a design tool to reconnect to the city’s agricultural past and as a model for cities of the future. First, I discuss Chula Vista’s history and contemporary context, including demographics. I review the existing urban agriculture policies Chula Vista has and compare them to other cities in California. The second part of the project is concerned with how to choose and develop a site for …
Colonization To Construction: Bridging The Gap Between Ancient Chamorro, Spanish Colonial & Modern Architecture On Guam, Dominic J. Lizama
Colonization To Construction: Bridging The Gap Between Ancient Chamorro, Spanish Colonial & Modern Architecture On Guam, Dominic J. Lizama
Undergraduate Honors Theses
Guam is an island in the Marianas that, over time, has experienced a rich cultural history brought about by its exposure to colonization, natural disasters, warfare and the continual influx of people and culture. Therefore, the architecture that exists on the island is one that divides itself into four distinct styles with each as a response to external forces that affected the island. By researching each of these styles, one is able to fully understand the holistic view of Guam’s history in order to design architecture that reflects the past with anticipation for the future. This thesis works to explore …
Postembryonic Polarity Modification In The Acoel Convolutriloba Longifissura, Eric Young, James M. Sikes Ph.D.
Postembryonic Polarity Modification In The Acoel Convolutriloba Longifissura, Eric Young, James M. Sikes Ph.D.
Undergraduate Honors Theses
Metazoans establish the bilateral body plan early in embryogenesis by patterning orthogonal body axes with polarity that is unaltered during the lifetime of most animals. While some organisms re-establish/modify body axes during regeneration and asexual reproduction, the acoel flatworm Convolutriloba longifissura is unusual in its ability to modify left-right (L-R) axis polarity during longitudinal fission. We have developed C. longifissura as a model for studying the mechanisms of L-R polarity modification during postembryonic development. Regeneration experiments have elucidated the temporal dynamics of midline re-specification, suggesting that parallel L-R axes replace the pre-existing midline prior to longitudinal fission. We have characterized …