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Distributions And Possible Roles Of Laminin, Fibronectin And Theirreceptor Subunits Integrin \Beta4 And \Alpha5 In Remodelling Of Extracellularmatrix During Decidualization In Rats, Ümi̇t Ali̇ Kayişli, Mevlüt Asar, Ramazan Demi̇r
Distributions And Possible Roles Of Laminin, Fibronectin And Theirreceptor Subunits Integrin \Beta4 And \Alpha5 In Remodelling Of Extracellularmatrix During Decidualization In Rats, Ümi̇t Ali̇ Kayişli, Mevlüt Asar, Ramazan Demi̇r
Turkish Journal of Biology
In the endometrium preparing for pregnancy, the stromal matrix components of the cells and their products begin structural differentiation due to endometrial receptivity. According to the hypothesis that 'extracellular matrix (ECM) proteins and adhesion molecules take roles in the structural differentiation as a result of endometrial decidualization', our aim was to determine the roles of ECM molecules laminin, fibronectin and adhesion proteins integrin \alpha5 and \beta4 in the decidulization and implantation by examining the emergence and changing distribution of these proteins. In this study, five experimental groups, consisting of 40 pregnant animals on pregnancy days 4-8, were used. Paraffin tissue …
Immunohistochemical Distribution Of Transforming Growth Factor Alpha,Laminin, Fibronectin And Desmin In Rat Ovary, Gökhan Akkoyunlu, İsmai̇l Üstünel, Ramazan Demi̇r
Immunohistochemical Distribution Of Transforming Growth Factor Alpha,Laminin, Fibronectin And Desmin In Rat Ovary, Gökhan Akkoyunlu, İsmai̇l Üstünel, Ramazan Demi̇r
Turkish Journal of Biology
Since the pure synthesis of transforming growth facto alpha (TGF\alpha) many attempts have been made in order to determine its distribution in various tissues. As a result of the complexitiy of the cyclic periods throughout experimental models, it is not easy to determine the distribution of TGF\alpha in the system. Especially the pre-and through-gestational pattern of TGF\alpha in rat ovary has not been reported fully. Furthermore, the shortage of literature about intracellular desmin and laminin, fibronectin of different intermediate filaments whether they have any interaction with TGF\alpha through this period, makes the subject worth discussing. Immunocytochemical techniques were utilized in …