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Rats Selectively Bred For Low Levels Of 50 Khz Ultrasonic Vocalizations Exhibit Alterations In Early Social Motivation, Howard C. Cromwell
Rats Selectively Bred For Low Levels Of 50 Khz Ultrasonic Vocalizations Exhibit Alterations In Early Social Motivation, Howard C. Cromwell
Howard Casey Cromwell
In rats, the rates of 50 kHz ultrasonic vocalizations (USVs) can be used as a selective breeding phenotype and variations in this phenotype can be an indicator of affective states. The 50 kHz USV is elicited by rewarding stimuli (e.g., food, sexual behavior) and therefore can express a positive affective state. Conversely, the 22 kHz USV is elicited by aversive stimuli (e.g., presence of a predator, social defeat) indicating a negative affective state. In the present study, we tested the effect of selectively breeding for 50 kHz USVs on a variety of maternal social/emotional behaviors in young rat pups (PND …