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Determining The Role Of Dnttip1: Piecing Together The Callipyge Sheep Muscle Hypertrophy Pathway, Kimberly Lutz
Determining The Role Of Dnttip1: Piecing Together The Callipyge Sheep Muscle Hypertrophy Pathway, Kimberly Lutz
The Journal of Purdue Undergraduate Research
Callipyge sheep have muscle hypertrophy in their loin and pelvic limbs due to a mutation in the DLK1-DIO3 imprinted gene cluster, which results in a 30–40% increase in muscle mass without altering live weight. There is also a change in the myosin gene expression causing an increase in fast twitch glycolytic fibers. Previous gene expression studies have shown that DNTTIP1 (terminal deoxynucleotidyl transferase interacting protein 1) is up-regulated in the callipyge muscle. DNTTIP1 is a transcription factor, meaning it binds to a specific DNA sequence to control the amount of mRNA produced. DNTTIP1 may regulate other genes, ultimately leading to …
Naturalized Offspring From An 85-Year-Old Chinese Chestnut (Castanea Mollissima) Planting: Stand Dynamics And Genetic Relationships, Amy Christel Miller
Naturalized Offspring From An 85-Year-Old Chinese Chestnut (Castanea Mollissima) Planting: Stand Dynamics And Genetic Relationships, Amy Christel Miller
Open Access Theses
Chestnuts, members of the genus Castanea , family Fagaceae, are valuable worldwide, and all species have noteworthy ecological, economic, and cultural importance in their native ranges. Historically, American chestnut (Castanea dentata (Marshall) Borkh.) was an abundant tree species in eastern North America until its decimation in the early 20 th century by chestnut blight, caused by the fungus Cryphonectria parasitica . To regain the benefits of this prized species in North America, efforts are ongoing to produce and introduce blight-resistant hybrids of C. dentata and the blight-resistant Chinese chestnut ( C. mollissima Blume). It is important that the C. …