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Does Belatacept Improve Patient/Graft Survival After 1 Year Versus Calcineurin Inhibitor Based Regimens?, Ashlie Burns
Does Belatacept Improve Patient/Graft Survival After 1 Year Versus Calcineurin Inhibitor Based Regimens?, Ashlie Burns
PCOM Physician Assistant Studies Student Scholarship
Objective: The objective of this selective EBM review is to determine whether or not belatacept improves patient/graft survival after 1 year versus calcineurin inhibitors based regimens.
Study Design: Review of one randomized controlled trial published in 2010 and two randomized controlled trials published in 2011 were used for this review and selected based on their relevance to the clinical question.
Data Sources: Studies were found using PubMed, and Medline Plus. Outcomes Measured: All three studies measured patient/graft survival after 12 months as either a primary or secondary outcome.
Results: Vincenti et al (2010) showed belatacept to …