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Immunoglobulin G Heavy Chain (Gm) Allotypes In Multiple Sclerosis, Janardan P. Pandey, Jean-Michel Goust, Jean-Philippe Salier, H. Hugh Fudenberg
Immunoglobulin G Heavy Chain (Gm) Allotypes In Multiple Sclerosis, Janardan P. Pandey, Jean-Michel Goust, Jean-Philippe Salier, H. Hugh Fudenberg
MUSC Faculty Journal Articles
Serum samples from 70 Caucasian patients with multiple sclerosis were typed for nine Gm markers. Significant association was found with the Gm 1,17;21 phenotype, and the relative risk for individuals with this phenotype was calculated at 3.6. The data indicate that Caucasians positive for Gm 1,17;21 are almost four times more likely to develop multiple sclerosis than those without this phenotype.