Digital Commons Network^™

Nonparametric Collective Spectral Density Estimation With An Application To Clustering The Brain Signals, Mehdi Maadooliat, Ying Sun, Tianbo Chen

Mathematics, Statistics and Computer Science Faculty Research and Publications

In this paper, we develop a method for the simultaneous estimation of spectral density functions (SDFs) for a collection of stationary time series that share some common features. Due to the similarities among the SDFs, the log‐SDF can be represented using a common set of basis functions. The basis shared by the collection of the log‐SDFs is estimated as a low‐dimensional manifold of a large space spanned by a prespecified rich basis. A collective estimation approach pools information and borrows strength across the SDFs to achieve better estimation efficiency. Moreover, each estimated spectral density has a concise representation using the …

A Structural And Dynamic Model For The Assembly Of Replication Protein A On Single-Stranded Dna, Luke A. Yates, Ricardo J. Aramayo, Nilisha Pokhrel, Colleen C. Caldwell, Joshua A. Kaplan, Rajika L. Perera, Maria Spies, Edwin Antony, Xiaodong Zhang

Biological Sciences Faculty Research and Publications

Replication Protein A (RPA), the major eukaryotic single stranded DNA-binding protein, binds to exposed ssDNA to protect it from nucleases, participates in a myriad of nucleic acid transactions and coordinates the recruitment of other important players. RPA is a heterotrimer and coats long stretches of single-stranded DNA (ssDNA). The precise molecular architecture of the RPA subunits and its DNA binding domains (DBDs) during assembly is poorly understood. Using cryo electron microscopy we obtained a 3D reconstruction of the RPA trimerisation core bound with ssDNA (∼55 kDa) at ∼4.7 Å resolution and a dimeric RPA assembly on ssDNA. FRET-based solution studies …

Doctoral‐Level Counseling Students’ Experiences Of Social Class Microaggressions, Caroline O'Hara, Jennifer M. Cook

College of Education Faculty Research and Publications

The authors recruited 11 doctoral‐level counseling students to participate in a study exploring the lived experiences of people who have encountered social class microaggressions (SCMs). Findings (consisting of 6 themes) suggest that SCMs are a distinct phenomenon arising from interpersonal and environmental exchanges that damage recipients. The authors present implications for counselor education and future research trajectories.

A Force Sensor That Converts Fluorescence Signal Into Force Measurement Utilizing Short Looped Dna, Golam Mustafa, Cho-Ying Chuang, William A. Roy, Mohamed M. Farhath, Nilisha Pokhrel, Yue Ma, Kazuo Nagawawa, Edwin Antony, Matthew J. Comstock, Soumitra Basu, Hamza Balci

Biological Sciences Faculty Research and Publications

A force sensor concept is presented where fluorescence signal is converted into force information via single-molecule Förster resonance energy transfer (smFRET). The basic design of the sensor is a ~100 base pair (bp) long double stranded DNA (dsDNA) that is restricted to a looped conformation by a nucleic acid secondary structure (NAS) that bridges its ends. The looped dsDNA generates a tension across the NAS and unfolds it when the tension is high enough. The FRET efficiency between donor and acceptor (D&A) fluorophores placed across the NAS reports on its folding state. Three dsDNA constructs with different lengths were bridged …

Meta-Analysis Of Non-Reactive Phosphorus In Water, Wastewater, And Sludge, And Strategies To Convert It For Enhanced Phosphorus Removal And Recovery, Kaushik Venkiteshwaran, Patrick J. Mcnamara, Brooke K. Mayer

Civil and Environmental Engineering Faculty Research and Publications

Current and future trends indicate that mining of natural phosphorus (P) reserves is occurring faster than natural geologic replenishment. This mobilization has not only led to P supply concerns, but has also polluted many of the world's freshwater bodies and oceans. Recovery and reuse of this nuisance P offers a long-term solution simultaneously addressing mineral P accessibility and P-based pollution. Available physical, chemical, and biological P removal/recovery processes can achieve low total P (TP) concentrations (≤100 μg/L) and some processes can also recover P for direct reuse as fertilizers (e.g., struvite). However, as shown by our meta-analysis of over 20,000 …

Reframing Understandings Of Cultural Influences On Learning Science, Jill Mcnew-Birren, Jennifer Gaul-Stout

College of Education Faculty Research and Publications

This review essay addresses issues raised in Valerie Frède’s paper entitled: Comprehension of the night and day cycle among French and Cameroonian children aged 7–8 years.

Muslim Women In The Diaspora: Shaping Lives And Negotiating Their Marriages, Enaya Othman

Arabic Languages and Literatures

This chapter uses Muslim communities in greater Milwaukee region in Wisconsin, United States as a case study to examine marriage negotiation among Palestinian women. I argue that Muslim women increasingly play a vital role in making changes to their gender roles and enhancing their marriage choices. Intermarriage outside their ethnic and national groups, increase in marriage age, and the rate of unmarried women become visible phenomena among second-generation Muslim. The decreasing number of suitable potential spouses drove Palestinian-American women to look outside their national and ethnic group for marriage partners. This made them prioritize their universal, religious identity as Muslims …

Smarthelp: Smartphone-Based Hemoglobin Level Prediction Using An Artificial Neural Network, Md Kamrul Hasan, Md. Munirul Haque, Riddhiman Adib, Jannatul F. Tumpa, Azima Begum, Rechard M. Love, Young Kim, Sheikh Iqbal Ahamed

Computer Science Faculty Research and Publications

Blood hemoglobin level (Hgb) measurement has a vital role in the diagnosis, evaluation, and management of numerous diseases. We describe the use of smartphone video imaging and an artificial neural network (ANN) system to estimate Hgb levels non-invasively. We recorded 10 second-300 frame fingertip videos using a smartphone in 75 adults. Red, green, and blue pixel intensities were estimated for each of 100 area blocks in each frame and the patterns across the 300 frames were described. ANN was then used to develop a model using the extracted video features to predict hemoglobin levels. In our study sample, with patients …

Global Connectivity And Function Of Descending Spinal Input Revealed By 3d Microscopy And Retrograde Transduction, Zimei Wang, Brian Maunze, Yunfang Wang, Pantelis Tsoulfas, Murray G. Blackmore

Biomedical Sciences Faculty Research and Publications

The brain communicates with the spinal cord through numerous axon tracts that arise from discrete nuclei, transmit distinct functions, and often collateralize to facilitate the coordination of descending commands. This complexity presents a major challenge to interpreting functional outcomes from therapies that target supraspinal connectivity after injury or disease, while the wide distribution of supraspinal nuclei complicates the delivery of therapeutics. Here we harness retrograde viral vectors to overcome these challenges. We demonstrate that injection of AAV2-Retro to the cervical spinal cord of adult female mice results in highly efficient transduction of supraspinal populations throughout the brainstem, midbrain, and cortex. …

Professional Philosophy, “Diversity,” And Racist Exclusion: On Van Norden’S Taking Back Philosophy: A Multicultural Manifesto, Grant J. Silva

Philosophy Faculty Research and Publications

No abstract provided.

Professional Skepticism: Practitioners’ Perceptions And Training Practices, Jodi L. Gissel

Accounting Faculty Research and Publications

While regulators criticize auditors for lacking appropriate professional skepticism (SEC, 2010, 2013; PCAOB, 2012), auditing standards lack a clear, consistent definition (Nelson, 2009; Hurtt, Brown-Liburd, Earley, & Krishnamoorthy, 2013), leaving application of professional skepticism “open to interpretation” (Glover & Prawitt, 2013, p. 2). If individual auditors view professional skepticism as open to interpretation (i.e., subjective), auditors may believe they are appropriately applying standards on professional skepticism based on their individual interpretations. However, if regulators apply a different definition of professional skepticism when reviewing auditors’ work, this may help explain ongoing criticisms from regulators stating auditors lack appropriate professional skepticism. The …

Unveiling Charge-Separation Dynamics In Cds/Metal–Organic Framework Composites For Enhanced Photocatalysis, Hai-Qun Xu, Sizhuo Yang, Xing Ma, Jier Huang, Hai-Long Wang

Chemistry Faculty Research and Publications

Photocatalytic water splitting for H₂ production becomes one of the most favorable pathways for solar energy utilization, while the charge-separation dynamics in composite photocatalysts is largely elusive. In the present work, CdS-decorated metal–organic framework (MOF) composites, namely, CdS/UiO-66, have been synthesized and exhibit high H₂ production activity from photocatalytic water splitting, far surpassing the MOF and CdS counterparts, under visible light irradiation. Transient absorption (TA) spectroscopy has been adopted in this report to unveil the charge-separation dynamics in CdS/UiO-66 composites, a key process that dictates their function in photocatalysis. We show that, in addition to the preferable formation …

Identifying Trippers And Non-Trippers Based On Knee Kinematics During Obstacle-Free Walking, Lauren C. Benson, Stephen C. Cobb, Allison S. Hyngstrom, Kevin G. Keenan, Jake Luo, Kristian M. O'Connor

Physical Therapy Faculty Research and Publications

Trips are a major cause of falls. Sagittal-plane kinematics affect clearance between the foot and obstacles, however, it is unclear which kinematic measures during obstacle-free walking are associated with avoiding a trip when encountering an obstacle. The purpose of this study was to determine kinematic factors during obstacle-free walking that are related to obstacle avoidance ability. It was expected that successful obstacle avoidance would be associated with greater peak flexion/dorsiflexion and range of motion (ROM), and differences in timing of peak flexion/dorsiflexion during swing of obstacle-free walking for the hip, knee and ankle. Three-dimensional kinematics were recorded as 35 participants …

Behavioral Inhibition And Activation As A Modifier Process In Autism Spectrum Disorder: Examination Of Self‐Reported Bis/Bas And Alpha Eeg Asymmetry, Hillary K. Schiltz, Alana J. Mcvey, Alexander Barrington, Angela D. Haendel, Bridget Dolan, Kirsten S. Willar, Sheryl Pleiss, Jeffrey S. Karst, Elisabeth M. Vogt, Christina C. Murphy, Kelsey Gonring, Amy V. Van Hecke

Psychology Faculty Research and Publications

The Modifier Model of autism spectrum disorder (ASD) suggests that phenotypic variability within ASD is rooted in modifier processes, such as the behavioral inhibition system (BIS) and behavioral activation system (BAS). Among a sample of 53 adolescents with ASD, this study examined associations between (a) self-reported BIS/BAS and frontal and parietal alpha electroencephalogram asymmetry and whether these indices related to (b) ASD severity (via the Autism Quotient), and/or (c) co-occurring anxiety and attention-deficit hyperactivity disorder (via Youth Self Report and Child Behavior Checklist). Findings showed that alpha asymmetry was associated with self-reported BAS scores, such that greater BAS was related …

Adenosquamous Carcinoma Of The Tongue, Yeshwant B. Rawal, Kenneth M. Anderson

School of Dentistry Faculty Research and Publications

A 51-year-old white female presented with a painful ulcer of the left ventrolateral tongue. An incisional biopsy confirmed a diagnosis of adenosquamous carcinoma. The adenosquamous carcinoma is an uncommon malignant tumor with histopathological features of a squamous carcinoma and an adenocarcinoma. A definitive diagnosis requires histopathological examination of a deep biopsy involving the submucosal tissue. This malignant tumor shows aggressive behavior with early invasive growth and a poor prognosis. The histopathological findings and differential diagnosis of a case of adenosquamous carcinoma of the tongue are discussed.

Epoxy Interlocking: A Novel Approach To Enhance Frp-To-Concrete Bond Behavior, Cheng Jiang, Baolin Wan, Yu-Fei Wu, John Omboko

Civil and Environmental Engineering Faculty Research and Publications

This paper presents a novel approach which can enhance the interfacial bond behavior between fiber reinforced polymer (FRP) composite material and concrete. Epoxy ribs are formed by grooving on the concrete surface before epoxy is applied. The dowel action from the epoxy ribs leads to an “epoxy interlocking” effect. The mechanism of the proposed epoxy interlocking approach was analyzed in this paper from both adhesion and interlocking aspects. Furthermore, the partial interaction of the epoxy interlocking was quantified and calibrated by experimental results. The epoxy interlocking in the tested specimens led to an 88.8% increase in bond strength on average. …

Automated Quantification And Evaluation Of Motion Artifact On Coronary Ct Angiography Images, Hongfeng Ma, Eric Gros, Scott G. Baginski, Zachary R. Laste, Naveen M. Kulkarni, Darin Okerlund, Taly Gilat Schmidt

Biomedical Engineering Faculty Research and Publications

Abstract

Purpose

This study developed and validated a Motion Artifact Quantification algorithm to automatically quantify the severity of motion artifacts on coronary computed tomography angiography (CCTA) images. The algorithm was then used to develop a Motion IQ Decision method to automatically identify whether a CCTA dataset is of sufficient diagnostic image quality or requires further correction.

Method

The developed Motion Artifact Quantification algorithm includes steps to identify the right coronary artery (RCA) regions of interest (ROIs), segment vessel and shading artifacts, and to calculate the motion artifact score (MAS) metric. The segmentation algorithms were verified against ground‐truth manual segmentations. The …

Using Case Work As A Pretest To Measure Crisis Leadership Preparedness, Jay L. Caulfield

Management Faculty Research and Publications

Today’s leaders must thrive in a world of turbulence and constant change. Unstable conditions frequently generate crises, emphasizing the need for crisis leadership preparedness, which is missing from many business curricula. Thus, the purpose of this work was to develop a learning module in crisis leadership preparedness. As a baseline measure or pretest, 217 graduate students were asked to analyze two crisis leadership cases during the first week of an entry leadership class. Content analysis provided the method to identify where student analyses fell short. These gaps in learning then informed the creation of student learning objectives. Applying inquiry-based learning, …

Development Of Domain Analysis To Predict Multi-Axial Flexible Airfield Pavement Responses Due To Gear And Environmental Loadings, Angeli Gamez, Jaime Hernandez, Imad L. Al-Qadi

Civil and Environmental Engineering Faculty Research and Publications

Flexible pavement design procedures use maximum mechanistic strains to predict service life via empirical transfer functions. The conventional method of using predefined point locations for potential damage may not accurately represent realistic pavement scenarios. For instance, flexible airfield pavement analysis mainly considers the critical strain at the bottom of the asphalt concrete (AC), which may not characterize near-surface cracking potential. In lieu of point strains, domain analysis, a new method, accounts for the multi-axial behavior of pavements, as inherently excited by three-dimensional (3-D) and nonuniform aircraft tire–pavement contact stresses. Initially applied on highway pavements considering truck tire loading, this approach …

Stochastic Water Balance Dynamics Of Passive And Controlled Stormwater Basins, Anthony J. Parolari, Steven Pelrine, Mark S. Bartlett

Civil and Environmental Engineering Faculty Research and Publications

Urbanization and changing rainfall intensities affect the performance of urban stormwater infrastructure, creating the necessity to design resilient stormwater systems. One proposed method to increase the resilience of stormwater infrastructure is the active control of system flows. To improve the understanding of actively-controlled urban water infrastructure function under variable hydro-climate, we develop a stochastic water balance model for stormwater retention and detention basins with both passive and actively-controlled outflow structures. Under active outflow control, the outflow valve is closed until the water level in the basin reaches a specified maximum at which point the valve opens and the basin empties. …

Phosphate Removal And Recovery Using Immobilized Phosphatebinding Proteins, Kaushik Venkiteshwaran, Nilisha Pokhrel, Faten Hussein, Edwin Antony, Brooke K. Mayer

Biological Sciences Faculty Research and Publications

Progress towards a more circular phosphorus economy necessitates development of innovative water treatment systems which can reversibly remove inorganic phosphate (P_i) to ultra-low levels (<100 μg L⁻¹), and subsequently recover the P_i for reuse. In this study, a novel approach using the high-affinity E. coli phosphate binding protein (PBP) as a reusable P_i bio-adsorbent was investigated. PBP was expressed, extracted, purified and immobilized on NHS-activated Sepharose beads. The resultant PBP beads were saturated with P_i and exposed to varying pH (pH 4.7 to 12.5) and temperatures (25–45 °C) to induce P_i release. Increase in …

Depression, Positive Thinking, Personal And Social Resourcefulness Among Caregivers Of Persons With Autism Spectrum Disorders, Abir K. Bekhet, Mauricio Garnier-Villarreal

College of Nursing Faculty Research and Publications

No abstract provided.

Promoting Team-Based Exercise Among African American Breast Cancer Survivors, Linda B. Piacentine, Karen Marie Robinson, Leslie J. Waltke, Judy A. Tjoe, Alexander V. Ng

College of Nursing Faculty Research and Publications

Physical activity benefits the health and well-being of breast cancer survivors (BCS). Yet, many African American survivors do not routinely exercise and have increased risk of poor outcomes. The purpose of this mixed-method study was to identify motivational factors compelling African American BCS to participate in a 14-week team walking program and to intend to continue exercise after the intervention concluded. Focus groups were held with participants (n = 12) before and after training. Content analysis discovered themes before the intervention: Not wanting to go at it alone, exercise not a life or treatment priority, cancer treatment affected activity, …

Comprehensive Evaluation Of Interventions: Eight Vital Parameters, Jaclene A. Zauszniewski, Abir K. Bekhet, Kayla Herbell

College of Nursing Faculty Research and Publications

Background It is critically important to determine the effectiveness of an intervention before it can be translated into clinical practice. However, the future implementation and sustainability of the intervention may be diminished if other intervention parameters are not assessed. This requires obtaining feedback from intervention recipients so interventions will be perceived as appealing, relevant, meaningful and beneficial to them; otherwise recipients may be unlikely to perform them over time, resulting in unsuccessful health outcomes.

Aim To propose the addition of two intervention parameters to the existing six-parameter model and provide examples from recent research of how each parameter can be …

A Global Analysis Of Corporate Litigation Risk And Costs, Matteo P. Arena, Stephen P. Ferris

Finance Faculty Research and Publications

We analyze a unique hand-collected international sample of 475 corporate lawsuits involving 361 publicly-traded defendant firms headquartered in 16 developed countries to explore how country factors influence litigation risk, equity market value, lawsuit outcomes, and settlement costs. Unlike U.S.-focused studies, we do not find a significant relation between stock turnover, equity performance, and the probability of litigation. Defendant firms headquartered in civil law countries or countries with less efficient judiciary systems face lower litigation risk and costs as well as less share price decline at filing. Countries whose courts are less independent demonstrate a significant bias against foreign defendant firms.

Book Review Of Fragmented Democracy: Medicaid, Federalism, And Unequal Politics, By Jamila Michener, Philip B. Rocco

History Faculty Research and Publications

No abstract provided.

Tell It Like It Is: The Effects Of Differing Responses To Negative Online Reviews, Carol L. Esmark Jones, Jennifer L. Stevens, Michael Breazeale, Brian I. Spaid

Management Faculty Research and Publications

Negative electronic word‐of‐mouth (eWOM) has a notable impact on a consumer's online purchase decisions and attitude toward a company or product. Despite substantial research examining this phenomenon, little attention has been given to the impact of responses to negative eWOM. The authors examine negative eWOM in the form of online reviews to understand how responses may impact a consumer’s product satisfaction and attitude toward the company. Three studies examine specific aspects of responses, including responder type, attribution, and severity of negative review. Consistent findings across the studies reveal while any response is better than no response, a fellow consumer responding …

Patient Safety Incentives For Residents: A Slippery Slope Or Reinforcement Of Desirable Behavior?, Kathryn Rapala

College of Nursing Faculty Research and Publications

In a study of error reporting in the care of Medicare beneficiaries, the US Department of Health and Human Services Office of Inspector General found that only 14% of patient safety events were reported.¹ A multicenter study found that 44.6% of residents were uncomfortable reporting diagnostic errors, possibly related to fear of repercussions and issues with the reporting system, among other factors.² A key question at the intersection of graduate medical education and patient safety is how to encourage resident and fellow error reporting.

The intervention described in the article, “Improving Resident and Fellow Engagement in Patient Safety …

Social Difficulties In Youth With Autism With And Without Anxiety And Adhd Symptoms, Alana J. Mcvey, Hillary Schiltz, Angela D. Haendel, Bridget Kathleen Dolan, Kirsten S. Willar, Sheryl Pleiss, Jeffrey S. Karst, Mary E. Carlson, Wendy Krueger, Christina C. Murphy, Christina L. Casnar, Brianna D. Yund, Amy V. Van Hecke

College of Education Faculty Research and Publications

Social difficulties inherent to autism spectrum disorder are often linked with co‐occurring symptoms of anxiety and attention deficit hyperactivity disorder (ADHD). The present study sought to examine the relation between such co‐occurring symptoms and social challenges. Parents of adolescents with autism (N = 113) reported upon social challenges via the social responsiveness scale (SRS) and anxiety and ADHD symptomatology via the Child Behavior Checklist. Results revealed differences in SRS scores across co‐occurring symptom subgroups (Anxiety, ADHD, Both, Neither)—namely, adolescents with autism and anxiety as well as those with autism, anxiety, and ADHD showed greater scores on the SRS than …

Impact Of Wide-Base Tires On Pavements: A National Study, Imad L. Al-Qadi, Jaime Hernandez, Angeli Gamez, Mojtaba Ziyadi, Osman Erman Gungor, Seunggu Kang

Civil and Environmental Engineering Faculty Research and Publications

This paper summarizes a multi-year effort comparing the new-generation wide-base tires (NG-WBT) and dual-tire assembly from a holistic point of view. The tires were compared considering not only pavement damage but also environmental impact. Numerical modeling, prediction methods, experimental measurements, and life-cycle assessment were combined to provide recommendations about the use of NG-WBT. A finite element (FE) approach considering variables that are usually omitted in the conventional analysis of flexible pavement was used for modeling pavement structures combining layer thickness, material properties, tire load, tire-inflation pressure, and pavement type (interstate and low volume). A prediction tool, ICT-Wide, was developed based …