Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 4 of 4
Full-Text Articles in Entire DC Network
Abundance Of The Species Clostridium Butyricum In The Gut Microbiota Contributes To Differences In Obesity Phenotype In Outbred Sprague-Dawley Cd Rats, Diana N. Obanda, Claudia Husseneder, Anne M. Raggio, Ryan Page, Brian Marx, Rhett W. Stout, Justin Guice, Diana Coulon, Michael J. Keenan
Abundance Of The Species Clostridium Butyricum In The Gut Microbiota Contributes To Differences In Obesity Phenotype In Outbred Sprague-Dawley Cd Rats, Diana N. Obanda, Claudia Husseneder, Anne M. Raggio, Ryan Page, Brian Marx, Rhett W. Stout, Justin Guice, Diana Coulon, Michael J. Keenan
Faculty Publications
© 2020 Elsevier Inc. Objectives: Gut microbiota profiles contribute to differences in obesity phenotype. We examined the abundance of the species Clostridium butyricum in relation to obesity phenotype. Methods: In outbred Sprague -Dawley rats we examined effects of dietary fat, resistant starch (RS), and a microbiota transplant on obesity phenotype. Using targeted qPCR, we examined the abundance of total gut bacteria and C. butyricum in relation to the propensity of obesity prone and obesity resistant rats to accumulate abdominal fat. Results: Before inclusion of dietary RS, obesity resistant (OR) rats had higher amounts of total bacteria, and C. butyricum compared …
Abundance Of The Species Clostridium Butyricum In The Gut Microbiota Contributes To Differences In Obesity Phenotype In Outbred Sprague-Dawley Cd Rats, Diana N. Obanda, Claudia Husseneder, Anne M. Raggio, Ryan Page, Brian Marx, Rhett W. Stout, Justin Guice, Diana Coulon, Michael J. Keenan
Abundance Of The Species Clostridium Butyricum In The Gut Microbiota Contributes To Differences In Obesity Phenotype In Outbred Sprague-Dawley Cd Rats, Diana N. Obanda, Claudia Husseneder, Anne M. Raggio, Ryan Page, Brian Marx, Rhett W. Stout, Justin Guice, Diana Coulon, Michael J. Keenan
Faculty Publications
© 2020 Elsevier Inc. Objectives: Gut microbiota profiles contribute to differences in obesity phenotype. We examined the abundance of the species Clostridium butyricum in relation to obesity phenotype. Methods: In outbred Sprague -Dawley rats we examined effects of dietary fat, resistant starch (RS), and a microbiota transplant on obesity phenotype. Using targeted qPCR, we examined the abundance of total gut bacteria and C. butyricum in relation to the propensity of obesity prone and obesity resistant rats to accumulate abdominal fat. Results: Before inclusion of dietary RS, obesity resistant (OR) rats had higher amounts of total bacteria, and C. butyricum compared …
Altered Gut Microbiota In Infants Is Associated With Respiratory Syncytial Virus Disease Severity, Jeffrey N. Harding, David Siefker, Luan Vu, Dahui You, John Devincenzo, J. F. Pierre, Stephania A. Cormier
Altered Gut Microbiota In Infants Is Associated With Respiratory Syncytial Virus Disease Severity, Jeffrey N. Harding, David Siefker, Luan Vu, Dahui You, John Devincenzo, J. F. Pierre, Stephania A. Cormier
Faculty Publications
© 2020 The Author(s). Background: Respiratory syncytial virus (RSV) is the number one cause of lower respiratory tract infections in infants. There are still no vaccines or specific antiviral therapies against RSV, mainly due to the inadequate understanding of RSV pathogenesis. Recent data suggest a role for gut microbiota community structure in determining RSV disease severity. Our objective was to determine the gut microbial profile associated with severe RSV patients, which could be used to help identify at-risk patients and develop therapeutically protective microbial assemblages that may stimulate immuno-protection. Results: We enrolled 95 infants from Le Bonheur during the 2014 …
Conserved And Variable Responses Of The Gut Microbiome To Resistant Starch Type 2, Zachary A. Bendiks, Knud E.B. Knudsen, Michael J. Keenan, Maria L. Marco
Conserved And Variable Responses Of The Gut Microbiome To Resistant Starch Type 2, Zachary A. Bendiks, Knud E.B. Knudsen, Michael J. Keenan, Maria L. Marco
Faculty Publications
Resistant starch type 2 (RS2), a dietary fiber comprised solely of glucose, has been extensively studied in clinical trials and animal models for its capacity to improve metabolic and systemic health. Because the health modulatory effects of RS2 and other dietary fibers are thought to occur through modification of the gut microbiome, those studies frequently include assessments of RS2-mediated changes to intestinal microbial composition and function. In this review, we identify the conserved responses of the gut microbiome among 13 human and 35 animal RS2 intervention studies. Consistent outcomes of RS2 interventions include reductions in bacterial α-diversity; increased production of …