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The Landscape Of Accessible Chromatin In Bovine Oocytes And Early Embryos, Hao Ming, Jiangwen Sun, Rolando Pasquariello, Lauren Gatenby, Jason Herrick, Ye Yuan, Carlos Pinto, Kenneth R. Bondioli, Rebecca L. Krisher, Zongliang Jiang
The Landscape Of Accessible Chromatin In Bovine Oocytes And Early Embryos, Hao Ming, Jiangwen Sun, Rolando Pasquariello, Lauren Gatenby, Jason Herrick, Ye Yuan, Carlos Pinto, Kenneth R. Bondioli, Rebecca L. Krisher, Zongliang Jiang
Faculty Publications
© 2020, © 2020 Informa UK Limited, trading as Taylor & Francis Group. Chromatin reorganization governs the regulation of gene expression during preimplantation development. However, the landscape of chromatin dynamics in this period has not been explored in bovine. In this study, we constructed a genome-wide map of accessible chromatin in bovine oocytes and early embryos using an improved assay for transposase-accessible chromatin with high-throughput sequencing (ATAC-seq) which revealed unique features of the accessible chromatin during bovine early embryo development. We found that chromatin accessibility is low in oocytes and 2-/4-cell embryos, followed by a significant increase in embryos during …
The Landscape Of Accessible Chromatin In Bovine Oocytes And Early Embryos, Hao Ming, Jiangwen Sun, Rolando Pasquariello, Lauren Gatenby, Jason Herrick, Ye Yuan, Carlos Pinto, Kenneth R. Bondioli, Rebecca L. Krisher, Zongliang Jiang
The Landscape Of Accessible Chromatin In Bovine Oocytes And Early Embryos, Hao Ming, Jiangwen Sun, Rolando Pasquariello, Lauren Gatenby, Jason Herrick, Ye Yuan, Carlos Pinto, Kenneth R. Bondioli, Rebecca L. Krisher, Zongliang Jiang
Faculty Publications
© 2020, © 2020 Informa UK Limited, trading as Taylor & Francis Group. Chromatin reorganization governs the regulation of gene expression during preimplantation development. However, the landscape of chromatin dynamics in this period has not been explored in bovine. In this study, we constructed a genome-wide map of accessible chromatin in bovine oocytes and early embryos using an improved assay for transposase-accessible chromatin with high-throughput sequencing (ATAC-seq) which revealed unique features of the accessible chromatin during bovine early embryo development. We found that chromatin accessibility is low in oocytes and 2-/4-cell embryos, followed by a significant increase in embryos during …