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How Cells Communicate: A Study Of Pkcdelta Phosphorylation Efficiency, Quamrul Hassan, Madeline Spencer
How Cells Communicate: A Study Of Pkcdelta Phosphorylation Efficiency, Quamrul Hassan, Madeline Spencer
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Communication is important for our bodies to function properly, especially at the cellular level. Our bodies utilize enzymes - specific proteins that catalyze chemical reactions - to effectively and quickly communicate many different kinds of messages. PKCdelta is an enzyme that has been implicated in membrane transport, as well as the formation of bile in the liver. Any misregulation of PKCdelta can lead to cholestasis and liver injury. Utilizing a coupled assay, we will determine the enzymatic activity of PKCdelta as it phosphorylates ATP using the UV spectrophotometer. After we have established the standard curve, we will determine the peak …