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Iowa State University

2003

Chemistry

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Heterostructures Of Polymer Photonic Crystal Films, Marc Egen, Rebecca Voss, Bernd Griesebock, Rudolf Zentel, Sergei Romanov, Clivia Sotomayor Torres Oct 2003

Heterostructures Of Polymer Photonic Crystal Films, Marc Egen, Rebecca Voss, Bernd Griesebock, Rudolf Zentel, Sergei Romanov, Clivia Sotomayor Torres

Rebecca Cademartiri

This paper describes ways to multilayer opaline films (opaline heterostructures) composed from functional opal layers of spheres with different lattice constants. At first various monodisperse colloidsboth cross-linked and un-cross-linkedwere prepared from methyl methacrylate, methyl α-chloroacrylate, and methyl α-bromoacrylate. These colloids can be crystallized into large, well-oriented opaline films with the help of a “drawing apparatus” by the method of crystallization in a moving meniscus. After annealing, a second opaline film can be crystallized on top of these films and so on. Electron microscopy inspection shows a sharp borderline between the sublayers and no disorder on both sides although the lattice …


Acrb Multidrug Efflux Pump Of Escherichia Coli: Composite Substrate-Binding Cavity Of Exceptional Flexibility Generates Its Extremely Wide Substrate Specificity, Edward Yu, Julio R. Aires, Hiroshi Nikaido Jan 2003

Acrb Multidrug Efflux Pump Of Escherichia Coli: Composite Substrate-Binding Cavity Of Exceptional Flexibility Generates Its Extremely Wide Substrate Specificity, Edward Yu, Julio R. Aires, Hiroshi Nikaido

Edward Yu

Gram-negative bacteria have, in general, much higher intrinsic levels of resistance to various antibiotics, antiseptics, dyes, and detergents than do gram-positive bacteria. This is, in part, due to the effectiveness of the outer membrane as a barrier. The porin channels exclude large compounds (for example, vancomycin) and drastically slow down the influx of most antibiotics, which are usually much larger than common nutrients. Most antibiotics and chemotherapeutic agents that act on targets in the cytosol must cross the inner, cytoplasmic membrane, usually by spontaneous diffusion, and this necessitates their being at least moderately lipophilic. These compounds can in principle diffuse …