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Iowa State University

1997

Medicine and Health Sciences

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Further Characterization Of A Complement-Sensitive Mutant Of A Virulent Avian Escherichia Coli Isolate, Theodore J. Kottom, Lisa K. Nolan, Michael Robinson, John Brown, Tom Gustad, Shelley M. Horne, Catherine W. Giddings Dec 1997

Further Characterization Of A Complement-Sensitive Mutant Of A Virulent Avian Escherichia Coli Isolate, Theodore J. Kottom, Lisa K. Nolan, Michael Robinson, John Brown, Tom Gustad, Shelley M. Horne, Catherine W. Giddings

Lisa K. Nolan

An attempt was made to characterize the mechanism of complement resistance operating in a virulent avian Escherichia coli isolate. Using flow cytometry to detect antibody to C3, we found that there was significantly more antibody bound to a complement-sensitive mutant of this wild type than to the parent organism, suggesting that more C3 subunits were bound to the wild type. Neither the wild type nor the mutant degraded C3. Further, the mutant was phagocytosed to a significantly greater degree than the wild type by cultured phagocytes in the presence of C5-deficient serum. These data suggest that the wild type is ...


A Highly Adherent Phenotype Associated With Virulent Bvg+-Phase Swine Isolates Of Bordetella Bronchiseptica Grown Under Modulating Conditions, Karen B. Register, Mark R. Ackermann Dec 1997

A Highly Adherent Phenotype Associated With Virulent Bvg+-Phase Swine Isolates Of Bordetella Bronchiseptica Grown Under Modulating Conditions, Karen B. Register, Mark R. Ackermann

Mark R. Ackermann

The ability of Bvg(-)-phase and Bvg(+)-phase Bordetella bronchiseptica swine isolates, grown under modulating or nonmodulating conditions, to adhere to swine ciliated nasal epithelial cells was determined. When virulent strains were cultivated at 37 degrees C in the Bvg+ phase, numerous adherent bacteria (approximately eight per cell, depending on the strain used) were observed. However, when such strains were grown under modulating conditions (23 degrees C), a significant increase in the level of attachment was seen, suggesting that B. bronchiseptica produces a Bvg-repressed adhesin under these conditions. bvg mutant strains, including an isogenic bvgS mutant, adhered minimally. Western blots ...


Iron Regulatory Protein 1 Is Not Required For The Modulation Of Ferritin And Transferrin Receptor Expression By Iron In A Murine Pro-B Lymphocyte Cell Line, Kevin Schalinske, Kenneth P. Blemings, Daniel W. Steffen, Opal S. Chen, Richard S. Eisenstein Sep 1997

Iron Regulatory Protein 1 Is Not Required For The Modulation Of Ferritin And Transferrin Receptor Expression By Iron In A Murine Pro-B Lymphocyte Cell Line, Kevin Schalinske, Kenneth P. Blemings, Daniel W. Steffen, Opal S. Chen, Richard S. Eisenstein

Kevin Schalinske

Iron regulatory proteins (IRPs) are cytoplasmic RNA binding proteins that are central components of a sensory and regulatory network that modulates vertebrate iron homeostasis. IRPs regulate iron metabolism by binding to iron responsive element(s) (IREs) in the 5* or 3* untranslated region of ferritin or transferrin receptor (TfR) mRNAs. Two IRPs, IRP1 and IRP2, have been identified previously. IRP1 exhibits two mutually exclusive functions as an RNA binding protein or as the cytosolic isoform of aconitase. We demonstrate that the BayF3 family of murine pro-B lymphocytes represents the first example of a mammalian cell line that fails to express ...


Safe Farm: 1996 Iowa Farm Injury And Fatality Data By County, Charles V. Schwab, Laura J. Miller Sep 1997

Safe Farm: 1996 Iowa Farm Injury And Fatality Data By County, Charles V. Schwab, Laura J. Miller

Agriculture and Environment Extension Publications

Injury and fatality data are listed by hospitalized or not hospitalized, and work or leisure related.


Effects Of Pasteurella Multocida Toxin On Porcine Bone Marrow Cell Differentiation Into Osteoclasts And Osteoblasts, S. M. Gwaltney, R. J. S. Galvin, K. B. Register, R. B. Rimler, Mark R. Ackermann Sep 1997

Effects Of Pasteurella Multocida Toxin On Porcine Bone Marrow Cell Differentiation Into Osteoclasts And Osteoblasts, S. M. Gwaltney, R. J. S. Galvin, K. B. Register, R. B. Rimler, Mark R. Ackermann

Mark R. Ackermann

The effect of Pasteurella multocida toxin (PMT) on porcine osteoclast and osteoblast differentiation was studied using in vitro cell culture systems. When grown in the presence of Vitamin D3, isolated porcine bone marrow cells formed multinucleated cells with features characteristic of osteoclasts. Exposure of bone marrow cells to Vitamin D3 and PMT during growth resulted in formation of increased numbers and earlier appearance of osteoclasts compared to controls. Ultrafiltered medium from PMT-treated cells likewise increased osteoclast numbers, suggesting that a soluble mediator may be involved in the action of PMT. When cell cultures were treated with fluorescein-labeled PMT, fluorescence was ...


A Novel Virus In Swine Is Closely Related To The Human Hepatitis E Virus, Xiang-Jin Meng, Robert H. Purcell, Patrick G. Halbur, James R. Lehman, Dale M. Webb, Tatiana S. Tsareva, Joseph S. Haynes, Brad J. Thacker, Suzanne U. Emerson Sep 1997

A Novel Virus In Swine Is Closely Related To The Human Hepatitis E Virus, Xiang-Jin Meng, Robert H. Purcell, Patrick G. Halbur, James R. Lehman, Dale M. Webb, Tatiana S. Tsareva, Joseph S. Haynes, Brad J. Thacker, Suzanne U. Emerson

Veterinary Pathology Publications and Papers

A novel virus, designated swine hepatitis E virus (swine HEV), was identified in pigs. Swine HEV crossreacts with antibody to the human HEV capsid antigen. Swine HEV is a ubiquitous agent and the majority of swine ≥3 months of age in herds from the midwestern United States were seropositive. Young pigs naturally infected by swine HEV were clinically normal but had microscopic evidence of hepatitis, and developed viremia prior to seroconversion. The entire ORFs 2 and 3 were amplified by reverse transcription–PCR from sera of naturally infected pigs. The putative capsid gene (ORF2) of swine HEV shared about 79 ...


Hospital Infant Formula Discharge Packagesdo They Affect The Duration Of Breast-Feeding?, Claibourne I. Dungy, Mary E. Losch, Daniel W. Rusell, Paul Romitti, Lois B. Dusdieker Jul 1997

Hospital Infant Formula Discharge Packagesdo They Affect The Duration Of Breast-Feeding?, Claibourne I. Dungy, Mary E. Losch, Daniel W. Rusell, Paul Romitti, Lois B. Dusdieker

Human Development and Family Studies Publications

Objective: To determine whether the duration of breastfeeding is affected by the contents of the hospital discharge package.

Design: A randomized clinical trial with 2 experimental interventions (a discharge package containing a manual breast pump only and a discharge package containing a commercially prepared infant formula and a manual breast pump) and a control group who received a commercially prepared infant formula discharge package only. Sociodemographic characteristics and information concerning prior births (including feeding methods) were obtained from each mother within 48 hours of her infant's birth. Sources of influence on the mother's feeding decision, maternal attitudes concerning ...


Small, Anionic, And Charge-Neutralizing Propeptide Fragments Of Zymogens Are Antimicrobial, Kim A. Brogden, Mark R. Ackermann, Kenneth M. Huttner Jul 1997

Small, Anionic, And Charge-Neutralizing Propeptide Fragments Of Zymogens Are Antimicrobial, Kim A. Brogden, Mark R. Ackermann, Kenneth M. Huttner

Veterinary Pathology Publications and Papers

Some inactive precursor proteins, or zymogens, contain small, amino terminus, homopolymeric regions of Asp that neutralize the cationic charge of the active protein during synthesis. After posttranslational cleavage, the anionic propeptide fragment may exhibit antimicrobial activity. To demonstrate this, ovine trypsinogen activation peptide, and frog (Xenopus laevis) PYL activation peptide, both containing homopolymeric regions of Asp, were synthesized and tested against previously described surfactant-associated anionic peptide. Peptides inhibited the growth of both gram-negative (MIC, 0.08 to 3.00 mM) and gram-positive (MIC, 0.94 to 2.67 mM) bacteria. Small, anionic, and charge-neutralizing propeptide fragments of zymogens form a ...


Use Of Ribotyping To Distinguish Bordetella Bronchiseptica Isolates, Karen B. Register, Agatha Boisvert, Mark R. Ackermann Jul 1997

Use Of Ribotyping To Distinguish Bordetella Bronchiseptica Isolates, Karen B. Register, Agatha Boisvert, Mark R. Ackermann

Veterinary Pathology Publications and Papers

A total of 113 Bordetella bronchiseptica strains, isolated from 11 different host species worldwide, were characterized by ribotyping with restriction enzyme PvuII. Sixteen distinct ribotypes were identified, and each ribotype contained five to seven restriction fragments ranging in size from 1.8 to 5.6 kb. Approximately 88% of the swine isoaltes were identified as ribotype 3 strains. Isolates from dogs also displayed little variation; 74.1% were found to be ribotype 4 strains. Strains obtained from the remaining nine host species belonged to 15 different ribotypes. There was no association between geographic location and ribotype. The technique which we ...


Reaction With Fructose Detoxifies Fumonisin B1 While Stimulating Liver-Associated Natural Killer Cell Activity In Rats, Z. Lu, W. R. Dantzer, E. C. Hopmans, V. Prisk, Joan E. Cunnick, Patricia A. Murphy, Suzanne Hendrich Mar 1997

Reaction With Fructose Detoxifies Fumonisin B1 While Stimulating Liver-Associated Natural Killer Cell Activity In Rats, Z. Lu, W. R. Dantzer, E. C. Hopmans, V. Prisk, Joan E. Cunnick, Patricia A. Murphy, Suzanne Hendrich

Food Science and Human Nutrition Publications

Fumonisin B1 (FB1) was reacted with fructose in an attempt to detoxify this mycotoxin. Fischer 344/N rats were initiated with diethylnitrosamine (15 mg/kg body weight) and then fed 69.3 μmol FB1/kg diet or 69.3 μmol FB1 reacted with fructose (FB1−fructose)/kg diet for 4 weeks. In comparison with the rats fed basal diet or FB1−fructose, the FB1-fed rats had significantly increased plasma cholesterol (P < 0.01), plasma alanine aminotransferase activity (P < 0.05), and endogenous hepatic prostaglandin production (P < 0.05). Placental glutathione S-transferase-positive and γ-glutamyl transferase-positive altered hepatic foci occurred only in the FB1-fed rats. Liver-associated natural killer (NK) cell activity was significantly decreased in the FB1-fed rats and increased in the group fed FB1-fructose, as compared with the basal group (P < 0.03). Therefore, modifying FB1 with fructose seems to prevent FB1-induced hepatotoxicity and promotion of hepatocarcinogenesis while stimulating liver-associated NK cell activity in rats.


Decreased Intracellular Survival Of An Fkpa Mutant Of Salmonella Typhimurium Copenhagen, Shelley M. Horne, Theodore J. Kottom, Lisa K. Nolan, Kevin D. Young Feb 1997

Decreased Intracellular Survival Of An Fkpa Mutant Of Salmonella Typhimurium Copenhagen, Shelley M. Horne, Theodore J. Kottom, Lisa K. Nolan, Kevin D. Young

Lisa K. Nolan

The fkpA gene of Salmonella typhimurium encodes a protein similar to the macrophage infectivity potentiator (Mip) proteins of Legionella pneumophila and Chlamydia trachomatis. Because Mip proteins enhance the ability of these intracellular pathogens to survive within macrophages and epithelial cells, we tested whether the product of the fkpA gene would have the same effect on the intracellular growth of a virulent strain of S. typhimurium. By a series of P22 transductions, the fkpA gene of S. typhimurium Copenhagen was replaced with the inactive fkpA1::omega-Cm gene from Escherichia coli, creating the mutant S. typhimurium KY32H1. The Copenhagen and KY32H1 strains ...


Regulation Of Brucella Abortus Catalase As A Defensive Mechanism Against Oxidative Stress , Jeonga Kim Jan 1997

Regulation Of Brucella Abortus Catalase As A Defensive Mechanism Against Oxidative Stress , Jeonga Kim

Retrospective Theses and Dissertations

Free radicals in the nature are harmful to organisms because they cause damage to tissues, cell membranes, proteins, and DNA. The animal immune system (cell mediated immune response) uses oxygen molecules to kill foreign organisms. B. abortus causes a cattle disease called brucellosis. The mechanism for bacteria to survive and adapt in the face of oxidative attack is thought to be important for understanding pathogenesis. This dissertation presents the response of B. abortus to oxidative stress and the regulation of catalase as a defensive mechanism;Different protein expression patterns were observed during oxidative stress by conducting 2-D protein gel analysis ...


Staff Evaluations And Perceptions Of Organizational Culture: Implications For Performance Improvement And Mental Healthcare Service Evaluation , Jeffrey Scott Kerber Jan 1997

Staff Evaluations And Perceptions Of Organizational Culture: Implications For Performance Improvement And Mental Healthcare Service Evaluation , Jeffrey Scott Kerber

Retrospective Theses and Dissertations

The researcher studied staff perceptions and evaluations regarding the provision of adult outpatient mental health services at a county medical center. Methods to improve the quality of adult outpatient mental health services were examined. Qualitative methods were employed to conduct a process and cultural assessment. The researcher addressed: (1) staff evaluations of crucial issues regarding performance improvement, (2) cultural issues relating to organizational change and development, (3) the interventive impact of focus group involvement, (4) the utility of qualitative methods for data analysis, (5) specific considerations for mental healthcare staff, and (6) how the evaluative process of a specific service ...


Analyzing The Effects Of Father's Antisocial Behavior On Mothers And Children: A Longitudinal Study Of Single-Parent Families , Marlene Renee Fisher Jan 1997

Analyzing The Effects Of Father's Antisocial Behavior On Mothers And Children: A Longitudinal Study Of Single-Parent Families , Marlene Renee Fisher

Retrospective Theses and Dissertations

This study examines changes in mothers' and adolescent mental health and behavioral measures in recently divorced single parent families. Overall, mothers in the study showed improvement in multiple measures of mental health over the course of this three year study. Single mother's problems with drinking also improved over time. Lower income women whose former spouse had problems with alcohol showed the most improvement in anxiety over time. Women who reported more physically abusive behavior prior to their divorce also reported the most improvement in depression over time. Women who continued to experience abuse in the post-divorce setting continued to ...


A Comparison Of Incidence Of Injury And Recovery Profiles Of Intercollegiate Women Basketball Players Sustaining Anterior Cruciate Ligament Ruptures , Alice Mcneill Mclaine Jan 1997

A Comparison Of Incidence Of Injury And Recovery Profiles Of Intercollegiate Women Basketball Players Sustaining Anterior Cruciate Ligament Ruptures , Alice Mcneill Mclaine

Retrospective Theses and Dissertations

Injuries to the anterior cruciate ligament (ACL) in women basketball players have come under recent scrutiny as it has become apparent that women athletes sustain more ACL injuries than their male counterparts. The purposes of this study were to examine (a) the effectiveness of intervention techniques in relation to sport return rates among women basketball players, (b) the effectiveness of injury prevention tactics in limiting anterior cruciate ligament injury rates, and (c) differences in these factors among NCAA Divisions I, II, and III;Data were collected from certified athletic trainers at forty-eight institutions across the nation. Representation was equally spread ...


The Functional Organization Of The Brain For Mental Imagery And Image Rotation: An Electroencephalographic Investigation , Harwant Singh Gill Jan 1997

The Functional Organization Of The Brain For Mental Imagery And Image Rotation: An Electroencephalographic Investigation , Harwant Singh Gill

Retrospective Theses and Dissertations

The intent of this dissertation was to reveal (by utilizing a set of cognitive tasks that are visuospatial in nature) how complex mental tasks are performed in the brain. Particular attention was devoted to the functional systems subserving the processes comprising the complex internal generation of mental images and their rotation;Utilizing Electroencephalography (more specifically, alpha power reduction), the functional system subserving the processes of mental rotation and mental image generation was identified. In this functional system, the occipital lobes are bilaterally involved in the initial encoding of visual information into a neural representation. These representations are then shunted to ...


Brucella Abortus Strain Rb51 Infection Of Bovine Trophoblast Epithelial Cells: Characterization Of Receptor Signaling And Bacterial Outer Membrane Proteins , Dominique Jules Jean Emmanuel Brees Jan 1997

Brucella Abortus Strain Rb51 Infection Of Bovine Trophoblast Epithelial Cells: Characterization Of Receptor Signaling And Bacterial Outer Membrane Proteins , Dominique Jules Jean Emmanuel Brees

Retrospective Theses and Dissertations

In 1995, a bovine brucellosis vaccine containing Brucella abortus strain RB51 was accepted for calfhood vaccination. However there is no objective serologic tests, such as ELISA, which detects antibodies specific for RB51-vaccinated cattle, and intravenous inoculation of pregnant animals with strain RB51 is followed by placentitis;To create an objective diagnostic test, antigenic outer membrane proteins from strain RB51 were isolated by Concanavalin A lectin affinity chromatography. One eluted protein of 35 kDa reacted in western blot analysis to every individual serum from strain RB51 and 2308 infected cattle. This protein may be a useful candidate antigen in developing a ...


Bias In Adoption Based Research: Methodological And Statistical Implications For Behavioral Genetics , Kristin Riggins-Caspers Jan 1997

Bias In Adoption Based Research: Methodological And Statistical Implications For Behavioral Genetics , Kristin Riggins-Caspers

Retrospective Theses and Dissertations

The present study investigated the methodological/statistical implications of adoptive parent knowledge for adoption methods used to estimate genetic and environmental contributions to individual differences. The sample used consisted of adoptees (n = 497) whose biological parents had been identified as either alcoholic, anti-social, or as a member of a control group in which neither alcoholism nor anti-social personality were diagnosed. The original purpose of the data set was content related in that it was intended to investigate genetic and environmental determinants of alcoholism and anti-social personality, as well as the interaction between genetic and environmental factors. The present study represents ...


Novel Materials And Methods For Solid-Phase Extraction And High-Performance Liquid Chromatography , Dianna Lynn Ambrose Jan 1997

Novel Materials And Methods For Solid-Phase Extraction And High-Performance Liquid Chromatography , Dianna Lynn Ambrose

Retrospective Theses and Dissertations

Solid-phase extraction (SPE) is one of the most popular sample preparation techniques for the isolation and preconcentration of organic compounds from aqueous samples. Modified porous polystyrene-divinylbenzene (PS-DVB) resins containing polar groups are superior for SPE of organic solutes from aqueous samples. These modified resins display excellent surface hydrophilicity and improved extraction efficiencies. Silicalite is a hydrophobic molecular sieve with an unusual crystal structure. Because of its unique structure, Silicalite adsorbs organic analytes from aqueous samples due to hydrophobic interactions;The ability of Silicalite and a lightly sulfonated PS-DVB resin to extract various organic test compounds from aqueous samples was compared ...


Patient Evaluations Of Mental Health Service Provision: Implications For Performance Improvement And Mental Healthcare Service Evaluation , Jeffrey Joseph Angera Jan 1997

Patient Evaluations Of Mental Health Service Provision: Implications For Performance Improvement And Mental Healthcare Service Evaluation , Jeffrey Joseph Angera

Retrospective Theses and Dissertations

The researchers explored methods for performance improvement at a hospital outpatient mental health clinic utilizing a qualitative patient evaluation. The study evaluated patient experiences receiving mental health services at a county hospital. Areas explored include: (1) mental health patient experiences interfacing with providers and ancillary services in the system, (2) patient suggestions for improvement, and (3) patient reactions to participating in a qualitative evaluation. The study examined all facets of service provision except confidential information expressed within the confines of the provider/patient relationship. The two primary data collection procedures included focus group discussions with patients only and focus groups ...


Cloning, Expression And Bioactivity Of Porcine Soluble Tnf Receptor 1 And The Comparison Of Pk(15) And Wehi 164(13)-Based Tnf Bioassays , Nancy A. Maroushek Boury Jan 1997

Cloning, Expression And Bioactivity Of Porcine Soluble Tnf Receptor 1 And The Comparison Of Pk(15) And Wehi 164(13)-Based Tnf Bioassays , Nancy A. Maroushek Boury

Retrospective Theses and Dissertations

Tumor necrosis factor (TNF) is a pro-inflammatory cytokine that activates both leukocytes and endothelium and facilitates the movement of inflammatory cells from circulation to sites of infection or injury. This activation may be beneficial and aid in host defense, or may be detrimental and mediate part of the pathophysiology of disease. Several porcine diseases, such as salmonellosis and mycoplasmal pneumonia, cause an increase in TNF production, which may be either beneficial or harmful to swine health. Two related studies were completed to develop assays and reagents to further study the role of TNF in porcine disease;In the first study ...


Regulation Of Water And Electrolyte Metabolism During Dehydration And Rehydration In Camels , Ali Abdullah Al-Qarawi Jan 1997

Regulation Of Water And Electrolyte Metabolism During Dehydration And Rehydration In Camels , Ali Abdullah Al-Qarawi

Retrospective Theses and Dissertations

The present study was undertaken to examine the effect of severe dehydration and rapid rehydration in electrolytes and body fluids homeostasis on the arabian camel (Camelus dromedarius), and to find out which pathway is responsible for the secretion of aldosterone in the dehydrated camel; either the renin-angiotensin axis or ACTH axis. In the first experiment ten dromedary camels were studied for a total of 29 days; 7 days under control conditions, 15 days of water deprivation and 7 days of rehydration in Bureidah (Saudi Arabia) during summer, 1996. Plasma electrolyte concentrations, plasma osmolality, packed cell volume (PCV), blood hemoglobin concentrations ...


Dose-Dependent Fumonisin B1 Hepatotoxicity And Hepatocarcinogenicity, Detoxification Of Fumonisin B1, And Suppression By Isoflavones Of Fumonisin B1-Promoted Hepatocarcinogenesis In Rats , Zhibin Lu Jan 1997

Dose-Dependent Fumonisin B1 Hepatotoxicity And Hepatocarcinogenicity, Detoxification Of Fumonisin B1, And Suppression By Isoflavones Of Fumonisin B1-Promoted Hepatocarcinogenesis In Rats , Zhibin Lu

Retrospective Theses and Dissertations

To determine threshold dose of fumonisin B1 (FB1) hepatotoxicity and hepatocarcinogenicity, rats were initiated with diethylnitrosamine (DEN) and were fed 12.5, 25 and 50 ppm FB1 for 4 weeks. Comparing with control rats, significant increases in plasma alanine aminotransferase activities (ALT) and plasma total cholesterol (TC) were found in animals fed 25 and 50 ppm FB1, and greater hepatic prostaglandin (PG) production in 50 ppm FB1 group. Placental glutathione S-transferase (PGST)- and gamma-glutamyltransferase (GGT)-positive altered hepatic foci (AHF) developed only in 25 and 50 ppm FB1 groups, and feeding 50 ppm FB1 significantly increased the percent areas of ...


Characterization Of The Developing Facial And Hypoglossal Motor Systems In The Neonatal Brazilian Opossum , Jack Jeffrey Swanson Jan 1997

Characterization Of The Developing Facial And Hypoglossal Motor Systems In The Neonatal Brazilian Opossum , Jack Jeffrey Swanson

Retrospective Theses and Dissertations

Aspects of development of the facial and hypoglossal motor systems were investigated in the neonatal Brazilian opossum, Monodelphis domestica. Monodelphis is a small pouchless marsupial whose young are born after 14 days of gestation in an extremely immature state while neurogenesis is still ongoing;1. The developmental time course for synaptogenesis in the facial motor nucleus (FMN) and the hypoglossal motor nucleus (HMN) was examined using immunohistochemistry against: synaptic vesicle-associated proteins, synaptophysin and synaptotagmin; a synaptic membrane protein, SNAP-25; a growth cone protein, GAP-43; and microtubule-associated proteins, Tau-1 and MAP-2. We found that appearance of synapse-associated proteins is delayed in ...


Diseases Chasing Money And Power: Breast Cancer And Aids Activism Challenging Authority, Amy Bix Jan 1997

Diseases Chasing Money And Power: Breast Cancer And Aids Activism Challenging Authority, Amy Bix

History Publications

Through the 1980s and early 1990s, the course of American health research was increasingly shaped by politically,aggressive activism for two particular diseases, breast cancer and AIDS (Acquired Immunodeficiency Syndrome). Even as national stakes rose, both in dollars spent and grow, ing demands on the medical system, breast cancer and AIDS advocates made government policy-making for research ever more public and con, croversial. Through skillful cultivation of political strength, interest groups transformed individual health problems into collective demands, winning notable policy influence in federal agencies such as the National lnsti, cutes of Health (NIH) and Food and Drug Administration (FDA ...


Family Financial Strain And Family Relationship Perceptions: Predictors Of Adolescent Depressed Mood , Kathryn Prosser Mayhew Jan 1997

Family Financial Strain And Family Relationship Perceptions: Predictors Of Adolescent Depressed Mood , Kathryn Prosser Mayhew

Retrospective Theses and Dissertations

Economic hardship, in the form of family financial strain has been associated with distress in both parents and children. The purpose of this study was to assess the effects of family financial strain on family relationship perceptions and adolescent depressed mood both cross-sectionally and prospectively. Structural equation modeling was utilized to elucidate family processes that were predictive of adolescent depressive mood. The cross-sectional results showed that family financial strain led to an increase in adolescents' depressive mood through an increase in parental depression and a decrease in nurturant parenting for father-daughter, mother-son, and mother-daughter dyads. For father-son dyads, fathers' depressed ...


The Effect Of Fluid Composition On Rehydration Following Heat And Exercise-Induced Dehydration , Melinda Lee Ray Jan 1997

The Effect Of Fluid Composition On Rehydration Following Heat And Exercise-Induced Dehydration , Melinda Lee Ray

Retrospective Theses and Dissertations

The influence of fluid composition on rehydration effectiveness was assessed following exercise and heat (65°C) exposure that produced a 2.6% body weight loss. In a randomized cross-over design, 18 subjects rehydrated for 3 h with water (H2O), and broths containing various sodium concentrations (LO: 31.5 mmol/l; MED: 109.5 mmol/l; HI: 159.5 mmol/l). Beverages were given in equal volumes every 20 min for a total volume equal to the body weight loss during dehydration. Significant differences (p < 0.05) among the treatments were determined using ANOVA. Body weight recovery was higher in MED compared witb LO (73 ± 3% vs 61 ± 4%). Plasma volume recovery was higher in MED (105 ± 1%) and HI (104 ± 2%) compared with H2O (97 ± 2%). Urine volume was higher in H2O (351 ± 57 ml) and LO (379 ± 29 ml) compared with MED (229 ± 18 ml) and HI (195 ± 21 ml). Plasma osmolality was higher in HI and MED compared with H2O, while the plasma sodium concentration was higher in LO, MED, and HI compared with H2O. The plasma potassium concentration was higher in LO compared with all other beverages;In the second study, 30 subjects were studied during 2 h of rehydration after a 2.5% body weight loss. In a randomized cross-over design, subjects rehydrated with water (H2O), chicken broth (CB: Na = 109.5; K = 25.3 mmol/l), a carbohydrate-electrolyte drink (CE: Na = 16.0; K = 3.3 mmol/l), and chicken noodle soup (SOUP: Na = 333.8; K = 13.7 mmol/l). Subjects ingested 175 ml at the start of rehydration and 20 min later; water was given every 20 min thereafter for a total volume equal to body weight loss during dehydration. Plasma volume recovery was greater in SOUP (99 ± 1%) and CB (98 ± 1%) compared with H2O (94 ± 1%). Urine volume was greater in CE (310 ± 30 ml) compared with CB (188 ± 20 ml). Urine osmolality was higher in CB and SOUP compared with CE. Urinary sodium concentration was higher in SOUP and CB compared with CE and H2O. These results suggest that including sodium in rehydration beverages improves whole body and plasma volume restoration.


Stress, Relationships, Distress, And Well-Being In High School Seniors , Kyle Lee Kostelecky Jan 1997

Stress, Relationships, Distress, And Well-Being In High School Seniors , Kyle Lee Kostelecky

Retrospective Theses and Dissertations

The purpose of this research project was to examine the impact of life events that are associated with major transitions that occur during late adolescence, specifically, for high school seniors. This was accomplished by investigating the role of family and nonfamily social support in the relationship between stressful life events and distress and well-being. The sources of support for the adolescents included their mother/step-mother, father/step-father, most important sibling, best male friend, best female friend, and most important adult at their school. Ensel and Lin's (1991) independent model, deterioration model, and counteractive model were examined. The examination of ...


Production, Purification, 14c Labeling, And Bioavailability Of Fumonisin B1 Produced By Fusarium Proliferatum Strain M-5991 , William Raymond Dantzer Jan 1997

Production, Purification, 14c Labeling, And Bioavailability Of Fumonisin B1 Produced By Fusarium Proliferatum Strain M-5991 , William Raymond Dantzer

Retrospective Theses and Dissertations

The production of FB1 by Fusarium proliferatum M-5991 was enhanced from 300 to 1400 [mu]moles/L by the addition of 0.75% corn hull extract (CHE) to modified Myro liquid medium (LM). Three continuous batch fermentations of F. proliferatum M-5991 in 10, 12, and 12 L modified Myro LM produced 28 mmoles of FB1 which were purified to >95% by a combination of XAD-16, C8, DEAE-Sepharose, and C18 chromatography. At day 12 of culture, (14C) -acetate was incorporated into 29 [mu]moles of FB1 in 50 ml modified Myro LM containing F. proliferatum which produced, after purification, 24 [mu ...


Sensitivity And Survival Of Escherichia Coli O157:H7 Isolates After X-Ray And Electron Beam Irradiation In Raw Ground Meat, Adelle Denise Chan Jan 1997

Sensitivity And Survival Of Escherichia Coli O157:H7 Isolates After X-Ray And Electron Beam Irradiation In Raw Ground Meat, Adelle Denise Chan

Retrospective Theses and Dissertations

No abstract provided.