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Articles 1 - 14 of 14
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Iron Regulatory Protein 1 Is Not Required For The Modulation Of Ferritin And Transferrin Receptor Expression By Iron In A Murine Pro-B Lymphocyte Cell Line, Kevin Schalinske, Kenneth P. Blemings, Daniel W. Steffen, Opal S. Chen, Richard S. Eisenstein
Iron Regulatory Protein 1 Is Not Required For The Modulation Of Ferritin And Transferrin Receptor Expression By Iron In A Murine Pro-B Lymphocyte Cell Line, Kevin Schalinske, Kenneth P. Blemings, Daniel W. Steffen, Opal S. Chen, Richard S. Eisenstein
Kevin Schalinske
Iron regulatory proteins (IRPs) are cytoplasmic RNA binding proteins that are central components of a sensory and regulatory network that modulates vertebrate iron homeostasis. IRPs regulate iron metabolism by binding to iron responsive element(s) (IREs) in the 5* or 3* untranslated region of ferritin or transferrin receptor (TfR) mRNAs. Two IRPs, IRP1 and IRP2, have been identified previously. IRP1 exhibits two mutually exclusive functions as an RNA binding protein or as the cytosolic isoform of aconitase. We demonstrate that the BayF3 family of murine pro-B lymphocytes represents the first example of a mammalian cell line that fails to express IRP1 …
Use Of Ultimate Load Theories For Design Of Drilled Shaft Sound Wall Foundations, Matthew J. Helmers
Use Of Ultimate Load Theories For Design Of Drilled Shaft Sound Wall Foundations, Matthew J. Helmers
Matthew J. Helmers
A study was performed to investigate the factors that affect the accuracy of the procedures used by the Virginia Department of Transportation for design of drilled shaft sound wall foundations. Field load tests were performed on eight inch and nine inch diameter drilled shafts, and the results were compared to theoretical solutions for ultimate lateral load capacity. Standard Penetration Tests were run in the field and laboratory strength tests were performed on the soils from the test sites. It was found that published correlations between blow count and friction angle for sands and gravels can be used to estimate friction …
Predicting Modes Of Toxic Action From Chemical Structure: Acute Toxicity In The Fathead Minnow (Pimephales Promelas), Steven P. Bradbury, Christine L. Russom, Steven J. Broderius, Dean E. Hammermeister, Robert A. Drummond
Predicting Modes Of Toxic Action From Chemical Structure: Acute Toxicity In The Fathead Minnow (Pimephales Promelas), Steven P. Bradbury, Christine L. Russom, Steven J. Broderius, Dean E. Hammermeister, Robert A. Drummond
Steven P. Bradbury
In the field of aquatic toxicology, quantitative structure-activity relationships (QSARs) have developed as scientifically credible models for predicting the toxicity of chemicals when little or no empirical data are available. In recent years, there has been an evolution of QSAR development and application from that of a chemical-class perspective to one that is more consistent with assumptions regarding modes of toxic action. The objective of this research was to develop procedures that relate modes of acute toxic action in the fathead minnow (Pimephales promelas) to chemical structures and properties. An empirically derived database for diverse chemical structures of acute toxicity …
Acute Toxicity And Behavioral Effects Of Chlorpyrifos, Permethrin, Phenol, Strychnine, And 2,4-Dinitrophenol To 30-Day-Old Japanese Medaka (Oryzias Latipes), Steven P. Bradbury, Patricia J. Rice, Charles D. Drewes, Theresa M. Klubertanz, Joel R. Coats
Acute Toxicity And Behavioral Effects Of Chlorpyrifos, Permethrin, Phenol, Strychnine, And 2,4-Dinitrophenol To 30-Day-Old Japanese Medaka (Oryzias Latipes), Steven P. Bradbury, Patricia J. Rice, Charles D. Drewes, Theresa M. Klubertanz, Joel R. Coats
Steven P. Bradbury
Five chemicals with different modes of action were evaluated in laboratory studies to determine their acute toxicity (48-h median lethal concentration [LC50]) and behavioral effects on 30-d-old Japanese medaka (Oryzias latipes). The order of toxicity for these xenobiotics was permethrin > chlorpyrifos > 2,4-dinitrophenol (2,4-DNP) > strychnine > phenol. The 48-h LC50s were significantly different and ranged from 0.011 to 24.1 mg/L. In addition, chlorpyrifos and permethrin accumulated in the tissues of juvenile O. latipes. Observations of five behavioral/morphological responses, including changes in equilibrium, general activity, startle response, and morphology (e.g., hemorrhage and deformities) were used as indicators of sublethal toxicity. Each chemical, with …
Internet Childhood Safety And Health Resource Guide, Steven A. Freeman, Scott D. Whitman, Roger L. Tormoehlen, Karla M. Embleton
Internet Childhood Safety And Health Resource Guide, Steven A. Freeman, Scott D. Whitman, Roger L. Tormoehlen, Karla M. Embleton
Steven A. Freeman
Purdue University's Agricultural Safety and Health Program, historically a paper-based directory of childhood safety and health resources, is now available on the World Wide Web (WWW). Advantages to WWW publication include: widespread availability, continuous updates, and low distribution costs. Disadvantages include: lack of acceptance by some Extension clientele, loss of portability, and initial difficulties in finding the publication's WWW location. The use of on-line resources has been moderate to date. However, a significant increase in utilization is expected as Internet access becomes less expensive and Extension educators and external clientele become more accustomed to using on-line resources.
Identification Of A Fish Host Of The Inflated Heelsplitter Potamilus Inflatus( Bivalvia: Unionidae) With A Description Of Its Glochidium, Kevin J. Roe, Andrew M. Simons, Paul Hartfield
Identification Of A Fish Host Of The Inflated Heelsplitter Potamilus Inflatus( Bivalvia: Unionidae) With A Description Of Its Glochidium, Kevin J. Roe, Andrew M. Simons, Paul Hartfield
Kevin J. Roe
A survey of the fishes of the lack Warrior River was undertaken to determine fish host(s) of the federally threatened inflated heelsplitter, Potamilus inflatus. Seven hundred-twenty individual fishes representing 30 species were examined; mussel glochidia were found on 10 individual fishes representing nine species. Potamilus inflatus glochidia were only found infesting one freshwater drum (Aplodinotus grunniens), which is concordant with previous findings for the genus Potamilus. The morphology of P. inflatus glochidia is described and compared to P. purpuratus.
Processing Small Quantities Of Walnut Logs For Lumber And Craft Items, Douglas D. Stokke, Peter Y. S. Chen, J. W. Van Sambeek
Processing Small Quantities Of Walnut Logs For Lumber And Craft Items, Douglas D. Stokke, Peter Y. S. Chen, J. W. Van Sambeek
Douglas D. Stokke
Many walnut plantation owners and woodworking hobbyists would like to process small quantities of walnut logs into lumber and discs for furniture and craft items. Various options exist for sawing, drying, and processing small diameter or short logs into lumber and cross-sectional discs. Portable band saws are a safe and inexpensive log breakdown option to commercial headsaw mills. Processing using the saw-dry-rip method will yield higher quantities of usable lumber from small diameter logs than the conventional saw-rip-dry method. Small quantities of lumber and discs can be inexpensively air dried under shelters or open sheds followed by approximately 15 to …
The Silviculture-Wood Quality Connection In Eastern Black Walnut, Douglas D. Stokke, Bruce E. Cutter, John E. Phelps
The Silviculture-Wood Quality Connection In Eastern Black Walnut, Douglas D. Stokke, Bruce E. Cutter, John E. Phelps
Douglas D. Stokke
The known effects of silvicultural practices on eastern black walnut (Juglans nigra L.) wood quality are reviewed. Since desirable quality differs from end user to end user, no specific recommendations are made.
Risk Analysis Of Black Walnut And Red Oak Plantations, Douglas D. Stokke, Stephen H. Kolison Jr., Jianbang Gan
Risk Analysis Of Black Walnut And Red Oak Plantations, Douglas D. Stokke, Stephen H. Kolison Jr., Jianbang Gan
Douglas D. Stokke
Risks and uncertainties are prevalent in timber production due to the nature and length of the production process. This paper examines the volatility of timber prices and the effects of some economic uncertainties and risks such as fluctuations in timber prices and the interest rate on the economic returns of black walnut and red oak plantations. Historical patterns of timber prices for black walnut and oaks are investigated and compared with those of other timber species and stock price. The sensitivity of economic returns from black walnut and red oak plantations to changes in timber prices and the discount rate …
A Computationally-Based Hazard Identification Algorithm That Incorporates Ligand Flexibility. 1. Identification Of Potential Androgen Receptor Ligands, Steven P. Bradbury, Ovanes Mekenyan, Julian Ivanov, Stoyan Karabunarliev, Gerald T. Ankley, Walter Karcher
A Computationally-Based Hazard Identification Algorithm That Incorporates Ligand Flexibility. 1. Identification Of Potential Androgen Receptor Ligands, Steven P. Bradbury, Ovanes Mekenyan, Julian Ivanov, Stoyan Karabunarliev, Gerald T. Ankley, Walter Karcher
Steven P. Bradbury
To advance techniques for screening large data sets of diverse structures for toxicologically active compounds, an algorithm was developed that is not dependent upon a predetermined and specified toxicophore or an alignment of conformers to a lead compound. Instead, the approach provides the means to identify and quantify specific global and local stereoelectronic characteristics associated with active compounds through a comparison of energeticallyreasonable conformer distributions for specific descriptors. To illustrate the algorithm, the stereoelectronic requirements associated with the binding affinity of 28 steroidal and non-steroidal ligands to the androgen receptor were defined. Common ranges of interatomic distances, atomic charges, and …
Influence Of Geographic Origin And Soil Properties On Color Of Black Walnut Veneer, Douglas D. Stokke, Edward C. Workman Jr., John E. Phelps, Felix Ponder Jr.
Influence Of Geographic Origin And Soil Properties On Color Of Black Walnut Veneer, Douglas D. Stokke, Edward C. Workman Jr., John E. Phelps, Felix Ponder Jr.
Douglas D. Stokke
Walnut veneer frorn sites in Missouri, Illinois, and Indiana was analyzed for color attributes and chemical properties. Veneer color also was compared to an industry color standard. Soil chemical and physical properties were measured on selected sites in each state. In general, walnut trees grown on soils with equal proportions of sand, silt, and clay have better veneer color attributes than trees grown on soils with high clay I sand or clay I silt ratios.
Sensors For Site-Specific Management, Stuart J. Birrell, J. W. Hummel, K. A. Sudduth
Sensors For Site-Specific Management, Stuart J. Birrell, J. W. Hummel, K. A. Sudduth
Stuart J. Birrell
Site-specific management (SSM, also known as precision farming, precision agriculture, prescription farming, etc.) is a management strategy that seeks to address within-field variability and to optimize inputs such as pesticides and fertilizers on a point-by-point basis within a field. By reducing over-application and under-application of nutrients and pesticides, this strategy has the potential to improve profitability for the producer and also to reduce the threat of groundwater or surface water contamination from agrichemicals. SSM is being adopted by innovative producers across the country. Agricultural equipment manufacturers, farm input suppliers, and a host of other businesses are working along with publicsector …
Effects Of Elevated Co2 And Defoliation On Grasses: A Comparative Ecosystem Approach, Brian J. Wilsey, James S. Coleman, Samuel J. Mcnaughton
Effects Of Elevated Co2 And Defoliation On Grasses: A Comparative Ecosystem Approach, Brian J. Wilsey, James S. Coleman, Samuel J. Mcnaughton
Brian J. Wilsey
Three plant species from each of three grassland ecosystems were grown under elevated (700 mL/m3) and ambient (350 mL/m3) CO2 and were defoliated or left undefoliated to test whether species response to elevated CO2 and grazing is related to evolutionary grazing history or to mode of photosynthesis. The three ecosystems represented a tropical grassland dominated by C4 species (the Serengeti of Africa), a temperate grassland dominated by a mixture of C3 and C4 species (Flooding Pampa of South America), and a northern temperate grassland dominated by C3 species (Yellowstone National Park of North America). Plants were grown in growth chambers …
An Insect-Based Detector Of Bovine Manure Odors, D. Raj Raman, Reid R. Gerhardt
An Insect-Based Detector Of Bovine Manure Odors, D. Raj Raman, Reid R. Gerhardt
D. Raj Raman
We designed, constructed, and tested a single-stream insect odormeter for the measurement of bovine manure odors. The biosensing element in the odormeter is a group of six gravid face flies (Musca autumnalis DeGeer) in a 360 mL chamber. A microphone, mounted above the chamber, senses sounds made by the flies’ activity. The microphone signal is processed by an analog root-mean-square power-measuring circuit connected to a computer data acquisition system. The apparatus allows electronic measurement of insect activity. Initial experiments demonstrate the feasibility of this system for odor detection (yes/no). Kinetic experiments show that a dose-response curve can be produced by …