Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 3 of 3
Full-Text Articles in Entire DC Network
Synthesis Of Phosphatidylethanolamine Lipids For Model Studies Of The Cell Membrane, John Hayford G. Teye-Kau
Synthesis Of Phosphatidylethanolamine Lipids For Model Studies Of The Cell Membrane, John Hayford G. Teye-Kau
Electronic Theses and Dissertations
Concerns about global warming have resulted in a surge of research into alternatives to fossil fuels. In recent years, biofuels have gained traction due to their low environmental impact. Biofuel production most commonly employs microorganisms to convert biomass to fuel for industrial and transportation applications. Compounds made in biofuel production, however, are toxic to cell membranes and disrupt their integrity, harming the microorganisms and limiting biofuel yield. A key to overcoming this challenge is understanding how fuels interact with microorganisms’ cell membranes, which perform a host of functions, including transport, cell recognition, transduction, and movement. Phospholipids are the cell membrane’s …
Study Of The Cell Membrane And The Synthesis Of Chimeric Human Bacterial Phospholipids, Opeyemi O. Tade
Study Of The Cell Membrane And The Synthesis Of Chimeric Human Bacterial Phospholipids, Opeyemi O. Tade
Electronic Theses and Dissertations
Phospholipid bilayers are the principal component of the cell membrane. Membranes ensure the maintenance of processes required for cells’ survival by regulating the inflow and outflow of nutrients and other molecules using membrane proteins. However, studying the cell membrane is challenging because of its complexity and small size. In-vitro membrane models made of phospholipids are important tools for studying membranes. In this work, we aim to study the fluidity of phospholipid bilayers of different lipids using general polarization (GP) of the fluorescent probe Laurdan as a measure. We will focus on the relative importance of head groups and fatty acids …
Preparation And Study Of Bacterial Membrane Models, Enoch Asimbisa
Preparation And Study Of Bacterial Membrane Models, Enoch Asimbisa
Electronic Theses and Dissertations
Fuel molecules are organic solvents that have disruptive effects on the bacterial membrane. This is a significant barrier in biofuel production, as it limits the fuel concentration that can be achieved through fermentation. One potential way of overcoming this barrier is to identify lipid compositions that can better withstand solvent stress, for which it is important to understand how organic solvents disrupt the membrane. Use of biophysical characterization techniques to quantify physical properties like fluidity and thickness will enable us to understand the mechanism by which solvents disrupt membranes. Native membranes are very complex, and we sought to develop in-vitro …