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Caloric Restriction Effects On Liver Mtor Signaling Are Time‐Of‐Day Dependent, Richa Tulsian, Nikkhil Velingkaar, Roman Kondratov
Caloric Restriction Effects On Liver Mtor Signaling Are Time‐Of‐Day Dependent, Richa Tulsian, Nikkhil Velingkaar, Roman Kondratov
Biological, Geological, and Environmental Faculty Publications
The regulation of mechanistic target of rapamycin (mTOR) signaling contributes to the metabolic effects of a calorie restriction (CR) diet. We assayed the effect of CR on the activity of mTOR complex 1 (mTORC1) and mTOR complex 2 (mTORC2) in the liver of mice at six different times across the day. CR effects on mTORC1 and mTORC2 activities were time-of-day dependent. CR induced mTORC1 activity at one time, reduced at two times and has no effect during other times. CR induced mTORC2 activity at one time of the day and has no effects at other times. Circadian clocks are implemented …
Examining Effects Of Arousal And Valence Across The Adult Lifespan In An Emotional Stroop Task, Samantha E. Tuft
Examining Effects Of Arousal And Valence Across The Adult Lifespan In An Emotional Stroop Task, Samantha E. Tuft
ETD Archive
As age increases, there is evidence that people tend to pay less attention to negative information, pay more attention to positive information, or both. There are many theoretical accounts that attempt to explain this positivity bias. In the current study, I examined positivity effects across the adult lifespan by evaluating competing predictions of two theories: Socioemotional Selectivity Theory, which is based in motivation, and Dynamic Integration Theory, which is based in capacity. Computer mouse tracking was used to examine effects across levels of Valence (negative, neutral, and positive) and Arousal (low, medium, and high) in an emotional Stroop task. Participants …
Recognition Memory Revisited: An Aging And Electrophysiological Investigation, Elliott C. Jardin
Recognition Memory Revisited: An Aging And Electrophysiological Investigation, Elliott C. Jardin
ETD Archive
This study provides a better understanding of contributing factors to age differences in human episodic memory. A recurrent finding in recognition memory is that older adults tend to have lower overall accuracy and tend to make fewer false-alarm errors in judging new items, relative miss errors (Coyne, Allen & Wickens, 1986; Danziger, 1980; Poon and Fozard 1980). Two possible causes for decline in these abilities include an age-related decrement in speed of processing (Salthouse 1991) and changes in information processing ability due to entropy (Allen, Kaufman, Smitch, & Propper 1998a; Mallik et al., in preparation). Additionally, age differences may be …
Recognition Memory Revisited: An Aging And Electrophysiological Investigation, Elliot C. Jardin
Recognition Memory Revisited: An Aging And Electrophysiological Investigation, Elliot C. Jardin
ETD Archive
This study provides a better understanding of contributing factors to age differences in human episodic memory. A recurrent finding in recognition memory is that older adults tend to have lower overall accuracy and tend to make fewer false-alarm errors in judging new items, relative miss errors (Coyne, Allen & Wickens, 1986; Danziger, 1980; Poon and Fozard 1980). Two possible causes for decline in these abilities include an age-related decrement in speed of processing (Salthouse 1991) and changes in information processing ability due to entropy (Allen, Kaufman, Smitch, & Propper 1998a; Mallik et al., in preparation). Additionally, age differences may be …