Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Entire DC Network
Rnase L Manipulates Macrophages In Innate Immunity And Tumor Growth, Xin Yi
Rnase L Manipulates Macrophages In Innate Immunity And Tumor Growth, Xin Yi
ETD Archive
RNase L is one of the key enzymes in the 2-5A system of interferon (IFN) action against viral infection and cellular proliferation. Tissue distribution analysis has revealed that RNase L is highly expressed in the spleen, thymus, lung, testis, intestine and most of immune cells such as T, B cells and macrophages. However, the physiological role of RNase L in the immune system is largely unknown. My thesis thus focused on studying the possible physiological role of RNase L in macrophages. By using bone marrow-derived macrophages (BMMs) from RNase L+/+and -/- mice, we demonstrated that RNase L is involved in …
Structural Basis Of Lman1 Cargo Capture In Er & Release In Ergic, Vaijayanti Das
Structural Basis Of Lman1 Cargo Capture In Er & Release In Ergic, Vaijayanti Das
ETD Archive
No abstract provided.