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The Development Of An In Vivo Spinal Fusion Monitor Using Microelectromechanical (Mems) Technology To Create Implantable Microsensors, Lisa Anne Ferrara
The Development Of An In Vivo Spinal Fusion Monitor Using Microelectromechanical (Mems) Technology To Create Implantable Microsensors, Lisa Anne Ferrara
ETD Archive
Surgical fusion of the spine is a conventional approach, and often last alternative, to the correction of a degenerative painful spinal segment. The procedure involves the surgical removal of the intervertebral disc at the problematic site, and the placement of a bone graft that is commonly harvested from the patients iliac crest and placed within the discectomized space. The surrounding bone is expected to incorporate and remodel into the bone graft to eventually provide an immobilized site. Spinal instrumentation often accompanies the bone graft to provide further immobility to the targeted site, thus augmenting the fusion process. However, the status …
Biocompatibility Of Osteoblast Cells On Titanium Implants, Dilip Ayyala Somayajula
Biocompatibility Of Osteoblast Cells On Titanium Implants, Dilip Ayyala Somayajula
ETD Archive
Adhesion and proliferation of UMR 106-01 osteoblast cells were studied on various surface modified titanium materials such as polished, sandblasted, anodized and alkaline treated. Anodization of polished surface in Hydrofluoric acid developed nano-tubes, while NaOH treatment produced spongy microporous morphology. Test samples were coated with non-adhesive protein bovine serum albumin and compared with fibronectin coated specimens. The adhesion study lasted for 4 hrs, where osteoblast cells were cultured in serum free medium. Polished titanium, anodized titanium and NaOH titanium have shown similar percentages of cell adherence. The proliferation study lasted for 48 hrs, where cells were initially allowed to adhere …