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Brigham Young University

Theses and Dissertations

2012

Simulation

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Mathematical Model And Experimental Exploration Of The Nanoinjector Lance Array, Nathan C. Toone Jul 2012

Mathematical Model And Experimental Exploration Of The Nanoinjector Lance Array, Nathan C. Toone

Theses and Dissertations

The Nanoinjector Lance Array has been developed to inject foreign material into thousands of cells at once using electrophoresis to attract and repel particles to and from the electrically-charged lances. A mathematical computer model simulating the motion of attracted or repelled proteins informs the design of the nanoinjection lance array system. The model is validated by accurately predicting protein velocity in electrophoresis experiments. A complete analysis of parameters is conducted via simulations and specific research questions regarding the counter electrode of the nanoinjector lance array system are explored using the model. A novel technique for fabricating lance arrays from collapsed …


Multi-Processor Computation Of Thrombus Growth And Embolization In A Model Of Blood-Biomaterial Interaction Based On Fluid Dynamics, Brandon Thomas Andersen Apr 2012

Multi-Processor Computation Of Thrombus Growth And Embolization In A Model Of Blood-Biomaterial Interaction Based On Fluid Dynamics, Brandon Thomas Andersen

Theses and Dissertations

This work describes the development and testing of a real-time three-dimensional computational fluid dynamics simulation of thrombosis and embolization to be used in the design of blood-contacting devices. Features of the model include the adhesion and aggregation of blood platelets on device material surfaces, shear and chemical activation of blood platelets, and embolization of platelet aggregates due to shear forces. As thrombus develops, blood is diverted from its regular flow field. If shear forces on a thrombus are sufficient to overcome the strength of adhesion, the thrombus is dislodged from the wall. Development of the model included preparing thrombosis and …


Performance Evaluation Of Optimal Rate Allocation Models For Wireless Networks, Ryan Michael Padilla Apr 2012

Performance Evaluation Of Optimal Rate Allocation Models For Wireless Networks, Ryan Michael Padilla

Theses and Dissertations

Convex programming is used in wireless networks to optimize the sending or receiving rates of links or flows in a network. This kind of optimization problem is formulated into a rate allocation problem, where each node in the network will distributively solve the convex problem and all links or flows will converge to their optimal rate. The objective function and constraints of these problems are represented in a simplified model of contention, interference, and sending or receiving rates. The Partial Interference model is an optimal rate allocation model for use in wireless mesh networks that has been shown to be …


Using Agent-Based Models To Understand Multi-Operator Supervisory Control, Yisong Guo Mar 2012

Using Agent-Based Models To Understand Multi-Operator Supervisory Control, Yisong Guo

Theses and Dissertations

As technology advances, many practical applications require human-controlled robots. For such applications, it is useful to determine the optimal number of robots an operator should control to maximize human efficiency given different situations. One way to achieve this is through computer simulations of team performance. In order to factor in various parameters that may affect team performance, an agent-based model will be used. Agent-based modeling is a computational method that enables a researcher to create, analyze, and experiment with models composed of agents that interact within an environment [12]. We construct an agent-based model of humans interacting with robots, and …