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Investigating The Anti-Cancer Properties Of Novel Hybrid 1,4-Dihydropyridine Derivatives In U-87mg Glioblastoma Cell, Tendai Hunyenyiwa
Investigating The Anti-Cancer Properties Of Novel Hybrid 1,4-Dihydropyridine Derivatives In U-87mg Glioblastoma Cell, Tendai Hunyenyiwa
Master's Theses
Glioblastoma is the most devastating of brain cancers with a very high death rate and a low survival rate of less than 15 months after diagnosis. Glioblastoma is a cancer of astrocytes which are the majority of the brain glial cells that support neurons and help create the blood-brain barrier among other functions. The current approach to treating this disease is surgical removal of the main tumor, followed by radiotherapy and limited chemical intervention by the use of temozolomide (TMZ). This disease is characterized by high invasion and recurrence after surgical removal of the main tumor as a result of …