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Emotion Regulation In Relation To Cognitive Functioning In The Preclinical Stages Of Dementia, Erica P. Meltzer

Dissertations, Theses, and Capstone Projects

Emotion regulation (ER) is essential for effective functioning in daily life. Research suggests that ER improves in older adulthood despite concomitant declines in cognition and the presumed neural substrates of ER. The current understanding of ER in older adulthood, and particularly of the relationship between ER and cognition in older adulthood, is limited. This is likely because the construct of ER is challenging to operationalize and, therefore, difficult to study.

The current study investigates ER in relation to cognitive functioning, specifically executive functioning and memory, in individuals with varying degrees of cognitive difficulties (i.e., in the preclinical stages of dementia). …

Consciousness, Perception, And Short-Term Memory, Henry F. Shevlin

Dissertations, Theses, and Capstone Projects

Dissertation Abstract: Consciousness, Perception, and Short-Term Memory

When we engage in almost any perceptual activity – recognizing a face, listening out for a phone-call, or simply taking in a sunset – information must be briefly stored and processed in some form of short-term memory. For philosophers attempting to develop an empirically grounded account of perception and conscious experience, it is therefore crucial to engage with scientific theories of the kinds of short-term memory mechanisms that underlie our moment-to-moment retention of information about the world. To that end, in this dissertation I review recent scientific evidence for a new form of …

The Bilingual Brain, Victoria A. James

Journal of Counseling and Psychology

This literature review explores the neurocognitive effects of the bilingual brain. Many areas of bilingualism are examined such as age of acquisition, which is when the second language is attained, and memory. The three types of bilingual memory are implicit memory, which is procedural memory, explicit memory, which is declarative memory, and episodic memory, which is autobiographical memory. In relation to the bilingual brain, cognition, control, and /lateralization are also reviewed. Finally, second language (L2) learning strategies are considered. The objective of this study is to obtain an understanding on how two or more languages are acquired and processed in …

Perceiving Oldness In Parietal Cortex: Fmri Characterization Of A Parietal Memory Network, Adrian Gilmore

Arts & Sciences Electronic Theses and Dissertations

The manner in which the human brain recognizes certain stimuli as novel or familiar is a matter of ongoing investigation. The overarching goal of this dissertation is to improve our understanding of how this may be accomplished. More specifically, work contained herein focuses on a recently described "parietal memory network" (PMN; Gilmore et al., 2015) that shows opposite patterns of activity when perceiving novel or familiar stimuli: deactivating in response to novelty, and activating in response to familiarity. Critically, our understanding of this network is based on explicit memory tasks, in which subjects are deliberately instructed to learn or remember …

The Mechanisms Underlying Cocaine-Induced Overexpression Of Basic Fibroblast Growth Factor (Bfgf, Fgf2), An Effect Reversed By Extinction, Madalyn Hafenbreidel

Theses and Dissertations

Drug addiction is characterized by compulsive drug use and chronic relapse despite negative consequences. Drug-induced structural and functional changes in the brain are thought to underlie these characteristics. One mechanism that may mediate these characteristics are growth factors, such as basic fibroblast growth factor (bFGF or FGF2), as they are necessary for cellular growth, survival, differentiation, and have roles in memory, mood, and anxiety disorders. bFGF mRNA and protein expression is increased following stimulant administration and is necessary for stimulant-induced changes in dendrites and behavioral sensitization. Moreover, addiction is maintained by cues associated with the drug, as they can can …

Recognition Training For Faces Across Age Gaps, William Blake Erickson

Graduate Theses and Dissertations

Face recognition is a problem that has theoretical and applied value. However, the fact of facial aging is rarely addressed in research and unmentioned in the major theories of face recognition. Facial aging also has ramifications for missing persons and fugitive cases, confounding attempts by law enforcement to recover these people whose last known images are years or decades out of date. This dissertation reports three studies aimed at measuring baseline age-gap recognition ability and testing various training regimens designed to increase accuracy rates for this unique kind of recognition task.

Does Sleep Enhance The Consolidation Of Implicitly Learned Visuo-Motor Sequence Learning?, Jeremy Viczko

Electronic Thesis and Dissertation Repository

Sleep has been shown to facilitate the consolidation (i.e., enhancement) of simple explicit (i.e., conscious) motor sequence learning (MSL). It remains unclear the degree to which this applies to implicit (i.e., unconscious) MSL. Employing reaction time and response generation tasks, we investigated the extent to which sleep is involved in consolidating implicit MSL, specifically whether the motor or the spatial cognitive representations of a learned sequence are enhanced by sleep, and whether these changes support the development of explicit sequence knowledge across sleep but not wake. Our results indicate that spatial and motor representations can be behaviourally dissociated for implicit …

Dancing In The Dark: Sleep-Dependent Motor Skill Memory Consolidation And Periodic Limb Movement Disorder, Valya Sergeeva

Electronic Thesis and Dissertation Repository

Periodic Limb Movement Disorder (PLMD) is a neurodegenerative disease characterized by dysfunction of the striatum and brief, repetitive limb movements during sleep. PLMD can severely disrupt non-rapid eye movement (NREM) sleep. Motor skills learning and memory consolidation are dependent on striatal activation, the latter enhanced by NREM sleep. Therefore, we investigated whether individuals with PLMD had learning and sleep-related memory deficits, and whether this putative deficit was related to sleep quality or symptom severity. 14 adults with a PLM index >15/hr underwent two nights (baseline, training) of polysomnographic recording. 15 age-matched healthy controls underwent three nights (baseline, undisturbed training and …

An Rct To Treat Learning Impairment In Traumatic Brain Injury, Nancy D. Chiaravalloti, Joshua Sandry, Nancy B. Moore, John Deluca

Department of Psychology Faculty Scholarship and Creative Works

Objective. To examine the efficacy of the modified Story Memory Technique (mSMT) to improve learning (ie, acquisition) and memory in participants with TBI. The mSMT is a behavioral intervention that teaches context and imagery to facilitate learning within 10 sessions over 5 weeks. Methods. A total of 69 participants with moderate-severe Traumatic Brain Injury (TBI), 35 in the treatment group and 34 in the placebo control group, completed this double-blind, placebo-controlled randomized clinical trial. A baseline neuropsychological assessment was administered, including questionnaires assessing everyday memory. Repeat assessments were conducted immediately posttreatment and 6 months following treatment. Participants in the treatment …

Sex Differences In Cognitive Decline In Mild Cognitive Impairment And Alzheimer's Disease, Juliann Thompson

Theses and Dissertations

Alzheimer's disease (AD) is the most common form of dementia and results in progressive cognitive decline, particularly in regards to memory (National Institute on Aging, 2012). Prior research has shown sex differences in brain-atrophy rates of AD patients, with women experiencing a higher rate of progression in volume reduction (Skup et al., 2011). This suggests that there may also be differences in cognitive functioning between sexes, particularly in the rate of cognitive decline with a more rapid disease progression for dementing females compared to dementing males. The current study monitored memory function longitudinally in approximately 200 total participants, 100 with …

The Effects Of Lipopolysaccharide-Induced Neuroinflammation On Learning And Forgetting In Juvenile Rats, Michele Barry

Seton Hall University Dissertations and Theses (ETDs)

The inability to remember events experienced very early in life is referred to as Infantile Amnesia (IA) and has been observed in both humans and animals. Over the years interest in the phenomenon waned, but has recently increased with the discovery of new neurobiological methods to study brain function (e.g., Callaghan, Li & Richardson, 2014). The neurobiological mechanism behind IA has yet to be determined, but several innovative theories have been developed with these new research methods. The neurogenesis hypothesis theorizes that increased neurogenesis during early development disrupts previously established memories. The hippocampus, an area that mediates both the memory …

A Novel Use Of The Deese-Roediger-Mcdermott Paradigm: Distinguishing Between Differential Memory Mechanisms In Emotional Literature, Alan John Yablonski Jr.

Senior Honors Projects, 2010-2019

To current knowledge, the emotional literature has not included the proposal to conceptualize experimental designs in terms of item vs. hippocampal-dependent relational memory representations. Through utilizing the Deese-Roediger-McDermott (DRM) paradigm the current study targets two memory mechanisms: item-specific memory (i.e., font color) and relational memory. In addition, relational-binding memory was also assessed. The current study consists of three hypotheses: (a) negatively-valenced critical lures will be correctly recalled by participants more than neutrally-valenced critical lures (increased relational memory for negatively-valenced words), (b) participants will more accurately recall studied negatively-valenced words with the correct color compared to neutrally-valenced studied words (increased item-specific …

Eye Movement Effects In Simulated Object Recognition Memory Impairment, Dmitriy Kazakov

Theses and Dissertations

Malingering is the purposeful fabrication of symptoms for secondary gain. Memory problems are the most reported symptom, and object recognition tests are often used in clinical settings to evaluate these claims. Past research has shown that eye movements can indirectly index memory, in that greater viewing is directed at studied stimuli 500-750 ms after display onset. The present study evaluated eye movements as a potential method of detecting feigned memory impairment. Forty-eight participants, half simulators, studied standardized images and took a memory test. Several levels of analysis were used to detect broad trends and brief effects. Simulators performed significantly worse …

The Effects Of Cognitive Rehabilitation For Improving Prospective Memory In Acquired Brain Injury, Emily M. Aiken

Masters Theses

Acquired Brain Injury (ABI) includes any damage to the brain resulting from traumatic (e.g. motor vehicle accident) or non-traumatic (e.g. stroke) incidence, that occurs after birth and is not resulting from genetic or congenital factors. Individuals with ABI report that prospective memory (PM) deficits are the most detrimental cognitive impairment following injury, persistently and negatively impacting their ability to function properly in everyday life. PM refers to the ability to remember to carry out intended tasks in the future, including the recall of both time and event regulated intentions. Using neuropsychological assessments to produce patient deficit profiles, this study examines …

The Influence Of Test Anxiety On Memory, James J. Malloy

Theses and Dissertations

The purpose of this study was to investigate the relationship between test anxiety and memory among a college population (N = 42). Specifically, the goal was to ascertain whether text anxiety had a measurable effect on memory, which was represented by scores on the Nelson-Denny reading comprehension subtest. Participants were divided into a stressed group (N = 22) and a non-stressed group (N = 20) in order to compare scores from test-takers with anxiety to those who do not. It was hypothesized that (a) test anxiety would have a significant impact on test results, (b) the non-stressed group would score …

Category Learning In Older Adulthood: A Study Of The Shepard, Hovland, And Jenkins (1961) Tasks., Rahel Rabi, John Paul Minda

Brain and Mind Institute Researchers' Publications

Shepard, Hovland, and Jenkins (1961) examined the categorization abilities of younger adults using tasks involving single-dimensional rule learning, disjunctive rule learning, and family resemblance learning. The current study examined category learning in older adults using this well-known category set. Older adults, like younger adults, found category tasks with a single relevant dimension the easiest to learn. In contrast to younger adults, older adults found complex disjunctive rule-based categories harder to learn than family resemblance based categories. Disjunctive rule-based category learning appeared to be the most difficult for older adults to learn because this category set placed the heaviest demands on …

The Representational-Hierarchical View Of Pattern Separation: Not Just Hippocampus, Not Just Space, Not Just Memory?, B. A. Kent, M. Hvoslef-Eide, L. M. Saksida, T. J. Bussey

Brain and Mind Institute Researchers' Publications

Pattern separation (PS) has been defined as a process of reducing overlap between similar input patterns to minimize interference amongst stored representations. The present article describes this putative PS process from the "representational-hierarchical" perspective (R-H), which uses a hierarchical continuum instead of a cognitive modular processing framework to describe the organization of the ventral visual perirhinal-hippocampal processing stream. Instead of trying to map psychological constructs onto anatomical modules in the brain, the R-H model suggests that the function of brain regions depends upon what representations they contain. We begin by discussing a main principle of the R-H framework, the resolution …

Neurogenesis-Mediated Forgetting Minimizes Proactive Interference., Jonathan R Epp, Rudy Silva Mera, Stefan Köhler, Sheena A Josselyn, Paul W Frankland

Brain and Mind Institute Researchers' Publications

Established memories may interfere with the encoding of new memories, particularly when existing and new memories overlap in content. By manipulating levels of hippocampal neurogenesis, here we show that neurogenesis regulates this form of proactive interference. Increasing hippocampal neurogenesis weakens existing memories and, in doing so, facilitates the encoding of new, conflicting (but not non-conflicting) information in mice. Conversely, decreasing neurogenesis stabilizes existing memories, and impedes the encoding of new, conflicting information. These results suggest that reduced proactive interference is an adaptive benefit of neurogenesis-induced forgetting.

The Impact Of Physical Activity On Memory: Recognition Differentiation Between Stimuli, Seth Spencer, C. Brock Kirwan

Journal of Undergraduate Research

Many studies have shown a correlation between physical exercise and healthy cognitive processing. It has been shown extensively that regular exercise has a positive impact on brain health. One example is a study that linked increased exercise with greater performance on as shown via a Stroop Color-Word test [1]. Similarly, regular exercise has been shown to be related to improved memory and object recognition [2]. Another study has shown that even a single session of exercise can alter functional connectivity in the brain as measured by the resting-state fMRI [3]. The problem with this literature is an utter lack of …

Phase Of Spontaneous Slow Oscillations During Sleep Influences Memory-Related Processing Of Auditory Cues., Laura J Batterink, Jessica D Creery, Ken A Paller

Brain and Mind Institute Researchers' Publications

UNLABELLED: Slow oscillations during slow-wave sleep (SWS) may facilitate memory consolidation by regulating interactions between hippocampal and cortical networks. Slow oscillations appear as high-amplitude, synchronized EEG activity, corresponding to upstates of neuronal depolarization and downstates of hyperpolarization. Memory reactivations occur spontaneously during SWS, and can also be induced by presenting learning-related cues associated with a prior learning episode during sleep. This technique, targeted memory reactivation (TMR), selectively enhances memory consolidation. Given that memory reactivation is thought to occur preferentially during the slow-oscillation upstate, we hypothesized that TMR stimulation effects would depend on the phase of the slow oscillation. Participants learned …

Metaphor And Memory: How Metaphors Instantiate Schemas In And Influence Memory Of Narrative, Sarah Elizabeth Cox

Honors Papers

Metaphoric frames are prominently featured in public discourse. They highlight certain aspects of the target issues they are used to describe, thereby encouraging specific patterns of inference. Our goal was to test whether they would influence memory as well. Building off prior work, we contrasted two metaphors for crime: virus and beast. In a pilot study, we identified specific causes, examples, and solutions to crime that were congruent with each frame (one but not the other; e.g., people thought “drug use” better exemplified a crime virus, whereas “murder” better exemplified a crime beast). Participants (n = 469) read or listened …

Context-Dependent Egr1 Expression In The Avian Hippocampus., Stephanie L Grella, Mélanie F Guigueno, David J White, David F Sherry, Diano F Marrone

Brain and Mind Institute Researchers' Publications

In mammals, episodic memory and spatial cognition involve context-specific recruitment of unique ensembles in the hippocampal formation (HF). Despite their capacity for sophisticated spatial (e.g., for migration) and episodic-like (e.g., for food-caching) memory, the mechanisms underlying contextual representation in birds is not well understood. Here we demonstrate environment-specific Egr1 expression as male brown-headed cowbirds (Molothrus ater) navigate environments for food reward, showing that the avian HF, like its mammalian counterpart, recruits distinct neuronal ensembles to represent different contexts.

Searching For The Neural Basis Of Reserve Against Memory Decline: Intellectual Enrichment Linked To Larger Hippocampal Volume In Multiple Sclerosis, James F. Sumowski, M. A. Rocca, V. M. Leavitt, G. Riccitelli, Joshua Sandry, John Deluca, Giancarlo Comi, Massimo Filippi

Department of Psychology Faculty Scholarship and Creative Works

Background and purpose: Active engagement in intellectually enriching activities (e.g. reading, hobbies) builds 'reserve' against memory decline in elders and persons with multiple sclerosis (MS), but the neural basis for this protective influence of enrichment is unknown. Herein the neuroanatomical basis of reserve against memory decline in MS patients is investigated. Methods: Relapse-onset MS patients (N = 187) underwent 3.0 T magnetic resonance imaging of the brain to quantify T2 lesion volume (T2LV) and normalized volumes of total brain, total white, total grey (using SIENAX) and thalamus, caudate, putamen, pallidum, amygdala and hippocampus (using FIRST). Patients completed a survey quantifying …

Cognitive Processes And Memory Differences In Recall And Recognition In Adults, Laura Elaine Fitzgerald

Walden Dissertations and Doctoral Studies

Eyewitness testimony is critical in both criminal court and civil court, so determining the most reliable method to gain information from witnesses is imperative. Past research in this area has focused on false memory, assisted recall, stress, and event perception. A gap exists in the current literature regarding the best method to gain the most accuracy in recall. The purpose of this study was to evaluate free recall, cued recall, and recognition, in an attempt to examine the accuracy of eyewitness memory. The study utilized a quantitative design to assess the accuracy of eyewitness memory as measured by results on …

Comparative Memory/Behavioral Symptoms Of Alzheimer's Disease: Eoad Vs. Load, Marcia Gale Roberson

Walden Dissertations and Doctoral Studies

Alzheimer's disease (AD) is a fatal disorder with no apparent cure. Early-onset AD (EOAD) occurs in individuals before the age of 65, and late-onset AD (LOAD) occurs in individuals age 65 and older. Past studies have proven that AD is fatal among Americans age 65 and older. The disease is characterized by impairments in memory and executive function as well as other cognitive and behavioral problems. The research questions addressed by this sequential, mixed-method study compared EOAD and LOAD by exploring common behavioral/cognitive symptoms and stage levels of AD. Research participants were recruited from the Alzheimer's Association who were members …

Individual Differences In Eyewitness Testimony, Noel A. Cal

Honors Undergraduate Theses

Eyewitness testimony plays a crucial role in the justice system. Misidentification from eyewitnesses was reported in 70% of 300 DNA exonerations of wrongfully convicted individuals (Wixted et al., 2015). Similarly, many convicts can also be set free because of juror’s faulty eyewitness recall during examination. Previous research indicated that females are more reliable in recall than men. However, these findings were not extensively examined with regards to time delay prior to the trial. Thus, it is important to systematically examine the various factors that influence eyewitness testimony.

The present study was designed to empirically examine the effects of gender, interview …

Practical Implications Of Learning From Unsuccessful Retrieval Attempts, Ann C. Rossmiller, James R. Houston

Williams Honors College, Honors Research Projects

Recent findings suggest that retesting oneself facilitates better learning than studying alone. Building off previous experiments where correcting participants has significantly increased correctness, the current study furthers our understanding about learning from unsuccessful retrieval attempts by manipulating the frequency of correction. Using a set of 42 associated word pairings, each participant was exposed to two blocks where they would memorize the word pairs. This was followed by two quizzing blocks and a final exam block where participants were asked to write down the associate to the stimulus presented on screen. Frequency of correction was manipulated during the quizzing blocks where …

Reflections Of The Social Environment In Chimpanzee Memory: Applying Rational Analysis Beyond Humans, Jeffrey R. Stevens, Julian N. Marewski, Lael J. Schooler, Ian C. Gilby

Jeffrey Stevens Publications

In cognitive science, the rational analysis framework allows modelling of how physical and social environments impose information-processing demands onto cognitive systems. In humans, for example, past social contact among individuals predicts their future contact with linear and power functions. These features of the human environment constrain the optimal way to remember information and probably shape how memory records are retained and retrieved. We offer a primer on how biologists can apply rational analysis to study animal behaviour. Using chimpanzees (Pan troglodytes) as a case study, we modelled 19 years of observational data on their social contact patterns. Much …

Political Conservatism Predicts Asymmetries In Emotional Scene Memory, Mark S. Mills, Frank J. Gonzalez, Karl Giuseffi, Benjamin Sievert, Kevin B. Smith, John R. Hibbing, Michael D. Dodd

Department of Psychology: Faculty Publications

Variation in political ideology has been linked to differences in attention to and processing of emotional stimuli, with stronger responses to negative versus positive stimuli (negativity bias) the more politically conservative one is. As memory is enhanced by attention, such findings predict that memory for negative versus positive stimuli should similarly be enhanced the more conservative one is. The present study tests this prediction by having participants study 120 positive, negative, and neutral scenes in preparation for a subsequent memory test. On the memory test, the same 120 scenes were presented along with 120 new scenes and participants were to …

Emotional Factors Affecting Face-Name Memory : The Role Of Valence And Arousal During Encoding, Stephanie Ann Kazanas

Legacy Theses & Dissertations (2009 - 2024)

The emotion literature has maintained that emotional stimuli are prioritized over neutral stimuli: Emotional words and images are detected faster, processed more automatically, and remembered better. However, the benefit from processing emotional stimuli can also be affected by valence, wherein some emotion advantages are driven by positive emotion and others by negative emotion. This is particularly evident in the face memory literature, in which researchers have investigated the role of expressed emotion in learning new faces. For example, some have found that happy faces are more memorable than angry and neutral faces. However, when comparing memory for happy faces with …