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Repeated Intracarotid Amobarbital Tests, T. Loddenkemper, H. H. Morris, Tara T. Lineweaver, C. Kellinghaus Dec 2014

Repeated Intracarotid Amobarbital Tests, T. Loddenkemper, H. H. Morris, Tara T. Lineweaver, C. Kellinghaus

Tara T. Lineweaver

Rationale:Our goal was to determine the frequency of repeated intracarotid amobarbital test (IAT) at our center and to estimate the retest reliability of the IAT for both language and memory lateralization. Methods: A total of 1,249 consecutive IATs on 1,190 patients were retrospectively reviewed for repeat tests. Results: In 4% of patients the IAT was repeated in order to deliver satisfactory information on either language or memory lateralization. Reasons for repetition included obtundation and inability to test for memory lateralization, inability to test for language lateralization, no hemiparesis during first test, no aphasia during first test, atypical vessel filling, and …


The Self-Reference Effect In Memory: A Meta-Analysis, Cynthia S. Symons, Blair T. Johnson Aug 2014

The Self-Reference Effect In Memory: A Meta-Analysis, Cynthia S. Symons, Blair T. Johnson

Blair T. Johnson

No abstract provided.


Memory Restoration, Julianne E. Henderson Ms. Aug 2014

Memory Restoration, Julianne E. Henderson Ms.

julianne e. henderson ms.

Memory maintains the power to shape our realities: it can rewrite the past, influence our future, and it constantly informs our present. When synaptic connections fire to retrieve desired information passing between neurons, memories appear to be amorphous, fluid, and impressionable. They are not set in stone, but rather open to edits and alterations belonging to the observer in question. Our recall is like time-lapse photography, with frames lined up side by side to create a living and dynamic succession of events that are rich with colors, sounds, scents, textures, and feelings. The human mind constantly oscillates back and forth …


Semantic Memory Functional Mri And Cognitive Function After Exercise Intervention In Mild Cognitive Impairment, J Carson Smith, Kristy A. Nielson, Piero Antuono, Jeri-Annette Lyons, Ryan J. Hanson, Alissa Butts, Nathan Hantke, Matthew D. Verber Jul 2014

Semantic Memory Functional Mri And Cognitive Function After Exercise Intervention In Mild Cognitive Impairment, J Carson Smith, Kristy A. Nielson, Piero Antuono, Jeri-Annette Lyons, Ryan J. Hanson, Alissa Butts, Nathan Hantke, Matthew D. Verber

Kristy Nielson

Mild cognitive impairment (MCI) is associated with early memory loss, Alzheimer's disease (AD) neuropathology, inefficient or ineffective neural processing, and increased risk for AD. Unfortunately, treatments aimed at improving clinical symptoms or markers of brain function generally have been of limited value. Physical exercise is often recommended for people diagnosed with MCI, primarily because of its widely reported cognitive benefits in healthy older adults. However, it is unknown if exercise actually benefits brain function during memory retrieval in MCI. Here, we examined the effects of exercise training on semantic memory activation during functional magnetic resonance imaging (fMRI). Seventeen MCI participants …


Prediction Of Cognitive Decline In Healthy Older Adults Using Fmri, John L. Woodard, Michael Seidenberg, Kristy A. Nielson, J Carson Smith, Piero Antuono, Sally Durgerian, Leslie Guidotti, Qi Zhang, Alissa Butts, Nathan Hantke, Melissa A. Lancaster, Stephen M. Rao Jul 2014

Prediction Of Cognitive Decline In Healthy Older Adults Using Fmri, John L. Woodard, Michael Seidenberg, Kristy A. Nielson, J Carson Smith, Piero Antuono, Sally Durgerian, Leslie Guidotti, Qi Zhang, Alissa Butts, Nathan Hantke, Melissa A. Lancaster, Stephen M. Rao

Kristy Nielson

Few studies have examined the extent to which structural and functional MRI, alone and in combination with genetic biomarkers, can predict future cognitive decline in asymptomatic elders. This prospective study evaluated individual and combined contributions of demographic information, genetic risk, hippocampal volume, and fMRI activation for predicting cognitive decline after an 18-month retest interval. Standardized neuropsychological testing, an fMRI semantic memory task (famous name discrimination), and structural MRI (sMRI) were performed on 78 healthy elders (73% female; mean age = 73 years, range = 65 to 88 years). Positive family history of dementia and presence of one or both apolipoprotein …


Spatial And Temporal Response Patterns On The Eight-Arm Radial Maze, Robert H.I. Dale Jun 2014

Spatial And Temporal Response Patterns On The Eight-Arm Radial Maze, Robert H.I. Dale

Robert H. I. Dale

Six maze-experienced hooded rats were timed during five trials on which they collected water from all arms of an eight-arm radial maze, then made five more choices. All subjects frequently exhibited a “task-completion pause:” The subjects rarely spent more than 1 sec in the center of the maze between choices until they had entered all eight arms, then stopped in the center of the maze. In contrast, the time spent in each arm gradually increased until all of the water had been obtained, then decreased slightly. Four subjects began every trial by choosing eight consecutive adjacent arms. The task-completion pause …


Cognitive Bias Modification: Past Perspectives, Current Findings, And Future Applications, Paula T. Hertel, Andrew Mathews Mar 2014

Cognitive Bias Modification: Past Perspectives, Current Findings, And Future Applications, Paula T. Hertel, Andrew Mathews

Paula T Hertel

Research conducted within the general paradigm of Cognitive Bias Modification (CBM) reveals that emotional biases in attention, interpretation, and memory are not merely associated with emotional disorders but contribute to them. After briefly describing research on both emotional biases and their modification, we examine similarities between CBM paradigms and older experimental paradigms used in research on learning and memory. We also compare the techniques and goals of CBM research to other approaches to understanding cognition/emotion interactions. From a functional perspective, the CBM tradition reminds us to use experimental tools to evaluate assumptions about clinical phenomena and more generally, about causal …