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Memory Matters Ii: Predictors Of Self-Care Behaviors In Young Adults With Type 1 Diabetes, Sari A. Soutor
Memory Matters Ii: Predictors Of Self-Care Behaviors In Young Adults With Type 1 Diabetes, Sari A. Soutor
Theses and Dissertations
Type 1 diabetes and associated hypoglycemia can result in verbal memory difficulties, yet the role of memory in daily diabetes self-care has not been evaluated for young adults. Subtests from two well-standardized memory measures were administered to 34 young adults with type 1 diabetes, aged 18-29, in this pilot study. Self-care behaviors were assessed through 24-hour diabetes care interviews, while HbAlc indicated metabolic control. Verbal associative memory uniquely accounted for 12% of the variance in blood glucose testing frequency (p p p p = .06. Single-trial verbal memory uniquely predicted 10% of the variance in metabolic control (p p < .05. Importantly, memory was the only significant predictor in each model, which indicates memory, rather than overall cognitive capacity or financial/educational resources, relates to self-care behaviors/health status. Memory, a novel factor not previously evaluated in the quest to better understand daily disease management for young adults with diabetes, is significantly related to central self-care behaviors and metabolic control. Memory predictors likely warrant additional research and clinical attention such that eventually, intervention studies might identify strategies or compensatory aids that could improve young adults' self-care behaviors and health status through facilitating better memory functioning.
The Effects Of Aniracetam Treatment On Cognitive Performance And Ampa Receptor Glur2 Subunit Expression After Moderate Fluid Percussion Injury In Rats, Anna Igorevna Baranova
The Effects Of Aniracetam Treatment On Cognitive Performance And Ampa Receptor Glur2 Subunit Expression After Moderate Fluid Percussion Injury In Rats, Anna Igorevna Baranova
Theses and Dissertations
In addition to the acute pathology produced by traumatic brain injury, there are chronic alterations that occur after the trauma, including a depressed state of neuronal activity (Feeney, 1991). This study included a preclinical testing of a novel treatment strategy focusing on increasing neuronal activity during the chronic hypofunctional posttraumatic stage. The present investigation tested the effects of repeated post-injury aniracetam administration on cognitive performance in the Morris water maze (MWM) and on the GluR2 - immunoreactivity and protein expression by Western blot analysis in the hippocampus. The first study examined the optimal dose of aniracetam in the MWM task. …